Clinical trials: Randomized-controlled Trial
Chronic Pain, Mild Cognitive Impairment
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and early cognitive decline.
- Trial name
- NCT07785648
- Testing
- Feeling of Being, Health Enhancement Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chemo-Mechanical Caries Removal
A Clinical and Microbiological Assessment of the Efficacy of Chemo-mechanical Caries Removal Versus Conventional Caries Removal Methods in Children: Randomized Controlled Clinical Trial
This study will be conducted to Assess the clinical and microbiological efficacy of chemomechanical caries removal (CarieMove® Gel) versus conventional excavation method in children.
- Trial name
- NCT06531148
- Testing
- Chemo-mechanical caries removal
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Physical Therapy, Health Promotion
Effects of Therapeutic Exercise on Quality of Life
The main objective was to determine the efficacy and safety of a therapeutic exercise program for students. Secondary objectives, determine the prevalence and intensity of musculoskeletal pain (MSP), disability, Health-Related…
- Conditions
- Physical Therapy, Health Promotion, Quality of Life
- Trial name
- NCT03529864
- Testing
- Exercise Therapy
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
White Spot Lesions
"Clinical Evaluation of Self-Assembling Peptides Versus Tri-Calcium Phosphate Based Varnish in Treatment of White Spot Lesions; Split-Mouth Randomized Clinical Trial"
Brief Summary: This randomized controlled clinical trial will evaluate the effectiveness of two remineralizing agents in the treatment of white spot lesions (WSLs) in young adults.
- Trial name
- SAP VS TCP (NCT07289932)
- Testing
- Curodont Repair (SAP P11-4), Clinpro White Varnish (Tri-Calcium Phosphate, TCP)
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Psychological Distress, Mental Health Wellness 1
A Guided Mobile-Based Perinatal Mindfulness Intervention
Psychological distress commonly occurs among women during perinatal period. maternal psychological distress can also bring negative influence on neonatal outcomes, such as infant health, child development or mother-child…
- Trial name
- NCT04876014
- Testing
- Guided Mobile-Based Perinatal Mindfulness Intervention
- Where
- Hong Kong
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Muscle Weakness
Randomized Controlled Trial Comparing Traditional Pelvic Floor Rehabilitation to Pilates in Increasing Pelvic Muscles Strength.
The objective of this randomized controlled trial is to determine whether a standardized Pilates exercise program can effectively strengthen pelvic floor muscles when compared with conventional pelvic muscle rehabilitation.
- Trial name
- NCT00549458
- Testing
- Pilates, Pelvic muscle rehabilitation therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Examine the Effect of Stress Ball Use During the Intrapartum Period on Labor Pain and Childbirth Experience in Primiparous Women
Effect of Stress Ball Use on Labor Pain and Birth Experience in Primiparous Women During Labor
INTRODUCTION Childbirth is a significant life experience for women, both physiologically and psychologically. The pain experienced during labor can vary depending on individual differences, cultural factors, and the course of…
- Trial name
- stressball (NCT07011355)
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Harran University
Intracytoplasmic Sperm Injection, Sperm
Sperm Selection by Rheotaxis and Thermotaxis in In-Situ Handmade Microfluidics of Fluidic Walls in the Same ICSI Plate
Microfluidics technologies are proving their capability to select suitable sperm for ICSI, especially those that take advantage of the rheotaxic properties of sperm migration.
- Conditions
- Intracytoplasmic Sperm Injection, Sperm, Microfluidics
- Trial name
- IS-MFluidics (NCT06243926)
- Testing
- Sperm selection for ICSI
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CREA Medicina de la Reproducción SL
Spontaneous Abortion in First Trimester
Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss
First trimester miscarriages are common. When the failed pregnancy does not pass spontaneously on its own, it is called a missed abortion.
- Trial name
- NCT02141555
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Trapezius Muscle Strain
Evaluation Of Peripheral Muscle Oxygenation In Individuals With Muscular Idiopathic Pain With Myofascial Release
Introduction: Neck Pain (NP) is considered a common idiopathic disorder in the general population. Oriented from incorrect executions during daily activities the DPO compromises the trapezius muscle that has a viscoelastic…
- Trial name
- NCT03882515
- Testing
- Myofascial Release, Continuous Surface Slip Technique, Without intervention
- Where
- Brazil
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
Pain, Fear
The Effect of ShotBlocker and Finger Puppet on Pain and Fear During Blood Drawing in Children
Blood sampling can cause pain, anxiety, and fear in children. Such negative experiences may cause the child to develop negative attitudes toward treatment and care procedures.
- Conditions
- Pain, Fear, Blood Sampling, Children
- Trial name
- NCT07654192
- Testing
- Distraction techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
CMV
Effect of Atorvastatin on Subclinical Atherosclerosis
Statin administration is supposed to reduce subclinical atherosclerosis by decreasing LDL cholesterol levels, possibly via lipid-independent anti-inflammatory effect.
- Trial name
- NCT04101136
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Pain, Postoperative, Ambulation Difficulty
Comparison of FAUCS vs. Misgav Ladach
This study aims to compare two techniques for performing a cesarean delivery: Misgav Ladach versus French Ambulatory Cesarean Section (FAUCS).
- Trial name
- NCT03812406
- Testing
- French Abulatory Cesrean Section, Misgav-Ladach
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
HIV-positive
Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique
Mobile phone SMS are increasingly used to promote positive health behaviour with an aim to improve health outcomes. However, robust data on the efficacy of SMS on health seeking behaviour and patient outcomes in resource-limited…
- Trial name
- SMSaude (NCT01910493)
- Testing
- SMS reminders
- Where
- Mozambique
- Volunteers
- 1,352 people, healthy volunteers welcome
- Sponsor
- Absolute Return for Kids
Healthy
The Impact of Local Anesthetic Dilution on Possible Blinding for Nerve Blocks
This study aims to determine the appropriate dosage of a placebo anesthetic to enable future placebo-controlled studies that can more accurately examine the effects of nerve blocks.
- Trial name
- NCT06668116
- Testing
- Ropivacaine 0,1%
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Aromatherapy, Prostate Cancer
Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
The study included 120 male patients who would undergo a prostate biopsy. Patients were divided into 3 groups as placebo group (n = 40), Levander group (N = 40), and Frankincense group (n = 40).
- Conditions
- Aromatherapy, Prostate Cancer, Anxiety
- Trial name
- NCT06119438
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin Training and Research Hospital
Osteoarthritis of the Knee
Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management
Three primary reasons prolong hospital stays following unilateral knee arthroplasty. Pain is the primary reason followed by opioid drowsiness and nausea/vomiting side effects.
- Trial name
- RFA (NCT02925442)
- Testing
- t-RFA, C-RFA, Control
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lyman Medical Research Foundation, Inc.
Heart Failure
A Safety, Tolerability, Pharmacokinetic Study of SHR-6934 Injection in Healthy Subjects
This study was a randomized, double-blind, single-dose and multi-dose, placebo-controlled phase Ⅰ clinical trial. Six dose groups were planned for the SAD part of the study and four dose groups were planned for the MAD part.
- Trial name
- NCT06700083
- Testing
- SHR-6934 injection
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Tramadol for Labor Analgesia
Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Tramadol for labor analgesia: a low risk placebo controlled randomised control trial
- Trial name
- NCT02999594
- Testing
- Tramadol Hydrochloride, Distilled Water
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Maulana Azad Medical College
Alzheimer Disease, Cognitive Impairment
Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
The objective of this proposed study is to evaluate the effect and safety of acupuncture combined therapy on cognitive function, daily living ability and quality of life of Alzheimer's disease by using the international dementia…
- Trial name
- NCT03810794
- Testing
- Acupuncture, Donepezil
- Where
- 3 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jian Pei,MD
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