Clinical trials: Randomized-controlled Trial
Irreversible Pulpitis
Diode Laser Pulpotomy of Mature Permanent Molars With Irreversible Pulpitis
Thirty six patients are included in this study. For each patient, a pulpotomy procedure is performed.
- Trial name
- NCT05427851
- Testing
- pulpotomy, Diode laser - fonalaser
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Obesity, Adult
Efficacy of Mindful Tai Chi on Obese or Overweight Adults: A Randomized Controlled Clinical Trial
Background: New weight-loss intervention programs are being studied to determine their effectiveness in helping overweight and obese individuals reach a healthy weight.
- Conditions
- Obesity, Adult, Healthy
- Trial name
- NCT01264029
- Testing
- Mindful Tai Chi Intervention, Mindfulness Meditation, Mall Walking
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Disaster, Older People
Disaster Preparedness of Older People
Disasters; It is an important public health problem of uncertain time, causing loss of life and property, having severe economic consequences, and causing serious health problems in the long term.
- Trial name
- SIMAH (NCT05859737)
- Testing
- Disaster Preparedness Education Program, Disaster and Emergency Management Presidency Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Motor Competence, Physical Activity, Balance
Effects of a Structured Motor Development Program Using Traditional Games on Motor Competence, Balance, Physical Activity Self-Efficacy, and Physical Activity Enjoyment in Primary School Children: A School-Based Randomized Controlled Trial
This randomized controlled trial aims to evaluate the effects of a 10-week structured motor development program based on traditional Turkish children's games on motor competence, balance performance, physical activity…
- Trial name
- TradGamesRCT (NCT07721831)
- Testing
- Traditional Turkish Children's Games Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ozlem Sinem USLU
Decrease Post Laproscopy Shoulder and Abdominal Pain
Multimodal Analgesic Technique for Control of Post-laproscopy Abdominal Pain
The advancement of laparoscopy and minimal access surgery has greatly influenced the evolution of anaesthetic techniques. However, postoperative pain intensity may be significant, with up to 40% of patients unsatisfied by routine…
- Trial name
- NCT03241602
- Testing
- Intraperitoneal lidocaine, Pulmonary Recruitment, Combined intraperitoneal lidocaine and pulmonary recruitment maneuver
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stargardt Disease
A Study of DC6001 Tablet in Healthy Chinese Adult Subjects
This study adopts a randomized, double-blind, parallel placebo-controlled dose-escalation design, consisting of two parts: Part 1 includes a single ascending dose (SAD) study plus a food effect (FE) study, and Part 2 is a…
- Trial name
- NCT07417566
- Testing
- DC6001
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Heronova Pharmaceuticals
Safe Sex
Evaluation of a Middle School Comprehensive Sexual Health Media Literacy Education Program
The purpose of this study is to conduct a randomized controlled trial of a media literacy education program for middle school students with the goal of enhancing decision-making skills to prevent early and risky sexual behavior…
- Trial name
- MASH (NCT02359422)
- Testing
- Media Aware-Sexual Health
- Where
- United States
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
Urinary Tract Infections
The Effect of Sonographic Bladder Compressive Technique for Bag Urine Collection in Pediatrics
Aim: to shorten the time of urination by bladder pressure stimulation in children less than 36 months of age who need urinalysis to exclude or diagnose urinary tract infections and to speed up the start time of antibiotics…
- Trial name
- NCT03152851
- Testing
- Pressure stimulus group
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Aging, Mobility Disability
The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults
To critically examine biological, clinical, and behavioral modulators of progressive resistance training-associated exercise response heterogeneity in physical function and whole-body metabolism in older adults.
- Trial name
- BRIO (NCT06940037)
- Testing
- Progressive Resistance Training, Health Education
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dental Caries
Optimised Fluoride Prevention by Double Rinse With Fluoride and Calcium
Aim: to determine the optimal Ca2+ concentration with 905 ppm F as NaF. Study design: Experimental study in 10 volunteers. Single blind mouth rinse with calcium lactate solution (150; 75; 0 mM Ca-lactate) is immediately followed…
- Trial name
- Fluor-Ca (NCT01473537)
- Testing
- calcium lactate solution
- Where
- Sweden
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Healthy
Effects of Breakfast Glycaemic Index on Cognition in Earlier or Later Chronotypes.
High glycaemic index (GI) breakfasts resulting in sharp rises in blood glucose may adversely affect memory and attention, particularly in the late postprandial phase (i.e., 120-180 minutes after breakfast).
- Trial name
- GlyCoBrainIn1 (NCT06916039)
- Testing
- immediate verbal memory after high GI breakfast, immediate verbal memory after low glycemic index breakfast
- Where
- Germany
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Anette Buyken
Influenza
Clinical Trial to Evaluate the Immunogenicity of an Adjuvanted Influenza Vaccine Among HCP
This randomized, double-blinded trial will assess humoral immune responses to adjuvanted, egg-based quadrivalent influenza vaccines compared to standard dose, egg-based quadrivalent influenza vaccines among healthcare personnel…
- Trial name
- EDUCATE (NCT06054269)
- Testing
- FLUAD Quadrivalent, FluQuadri
- Where
- 2 sites in Peru
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
LGBTQ, Sexual Behavior
A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
This study is to test the efficacy of an online CBT intervention (EQuIP) that addresses the pathways through which minority stress compromises LGBTQ young adults' co-occurring mental (e.g., depression) and behavioral (e.g.…
- Trial name
- NCT04408469
- Testing
- Online EQuIP, Self-monitoring control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Tuberculosis, Pulmonary, HIV Coinfection
Pharmacist-Led Intervention to Improve TB Treatment Adherence
The goal of this clinical trial is to compare the adherence of co-morbid patients in control and experimental group The main question[s]it aims to answer are: 1.
- Trial name
- RA-15041995 (NCT06608069)
- Testing
- Educational counselling
- Where
- 2 sites in Malaysia
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Endoscopy, Digestive System
Impact of Timing of Premedication on Mucosal Visibility During Endoscopy-A Randomized Controlled Trial
UGI endoscopy(esophagogastroduodenoscopy) is the main diagnostic modality for direct visualization ,real time assessment and interpretation of findings encountered.
- Trial name
- ENDO (NCT06581783)
- Testing
- Simethicone plus NAC
- Where
- India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Dental Implant
Clinical Evaluation of Stability of Implants Placed in Partially Edentulous Maxilla With Poor Bone Quality Via New Reverse Drilling Technique Versus Osteotome Technique.
The study will compare between osteotome technique and New Reverse Drilling Technique in the placement of dental implant in posterior maxilla , primary outcome will be Implant stability that will be measured by Periotest device .
- Trial name
- NCT04541641
- Testing
- New Reverse Drilling technique, osteotome technique
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hand Injuries, Upper Extremity Injury
Lower Tourniquet Pressure Study
This study design is a prospective, double-blinded, randomized controlled trial evaluating the quality of bloodless surgical field with lower tourniquet pressures based on systolic blood pressure (SBP) compared to standard…
- Trial name
- NCT04994405
- Testing
- Tourniquet Pressure
- Where
- 3 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Overweight and Obesity
Effect of High-intensity Interval Training on Metabolic Fitness in Overweight Males.
Background and aims: The purpose of this study was to evaluate the effect of high intensity interval training (HIIT) on body composition, physical fitness, metabolic fitness and muscle histology in men with overweight or obesity…
- Trial name
- CALIN (NCT02798666)
- Testing
- High intensity exercise training, Continuous exercise training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Ghent
Neisseria Gonorrhea
Safety and Immunogenicity Study of a Multivalent Gonorrhoea Vaccine
The main goal of this trial is to evaluate the safety and immunogenicity of the candidate N. gonorrhoeae vaccine, LTB-NG6.
- Trial name
- LTBNG601 (NCT07758972)
- Testing
- LTB-NG6, Sodium Chloride 0.9%
- Where
- Germany
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- LimmaTech Biologics AG
Compliance, Tobacco Use Cessation
Evaluation of Efficacy of Different Methods of Tobacco Cessation Interventions Among BEST Employees in Mumbai
Tobacco use is the single most preventable cause of premature adult death globally. It is one of the major causes of death and disease in India, accounting for nearly 0.9 million deaths every year.
- Trial name
- NCT02397369
- Testing
- Tobacco users: Self Help, Tobacco users:Telephonic counseling, Tobacco users:Behavioural therapy Only
- Where
- India
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
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