Clinical trials: Randomized-controlled Trial
Hypotension on Induction, Hypnotic Intoxication
Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion
To compare haemodynamics and bispectral index values between conventional bolus propofol induction and target-controlled propofol infusion.
- Trial name
- NCT04291794
- Testing
- Propofol, Propofol Injection [Diprivan]
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Motor-Cognitive Function, Dual-Task Walking
Effects of Adapted Argentine Tango Training Frequency on Dual-Task Walking
This randomized controlled trial will examine whether the frequency of adapted Argentine tango training affects walking and cognitive function in adults aged 55 to 60 years when the total weekly intervention time is kept the…
- Conditions
- Motor-Cognitive Function, Dual-Task Walking, Balance
- Trial name
- AAT-FREQ (NCT07800494)
- Testing
- Distributed Adapted Argentine Tango Training, Concentrated Adapted Argentine Tango Training, Health Education and Low-Intensity Stretching
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xi'an Medical University
Yoga-Based Recovery Course, Control
ED Recovery Course Online RCT
The purpose of this study is to examine whether the Eat Breathe Thrive (EBT) Yoga for Eating Disorder Recovery online course is effective in supporting eating disorder recovery.
- Trial name
- NCT04557566
- Testing
- EBT yoga-based eating disorder course
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Preterm Birth, Obstetric Labor, Premature
Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial
Azithromycin is an antibiotic that is effective against bacteria that been associated with preterm birth (PTB). The purpose of this study is to evaluate if the addition of azithromycin prior to exam indicated cerclage prolongs…
- Conditions
- Preterm Birth, Obstetric Labor, Premature, Obstetric Labor Complications, Pregnancy Complications
- Trial name
- ALEC (NCT05132829)
- Testing
- Azithromycin 1 gram IV, Cefazolin and indomethacin
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Perineal Infection, Maternal Infections Affecting Fetus or Newborn
Different Perineal Preparations Before Vaginal Birth to Maternal/Neonatal Infections and Cost Effectiveness
The vaginal microbiome plays a crucial role in women's health, primarily composed of beneficial bacteria such as Lactobacillus, which help maintain an acidic environment in the vagina, preventing the growth of pathogens.
- Conditions
- Perineal Infection, Maternal Infections Affecting Fetus or Newborn, Cost Effectiveness
- Trial name
- NCT06880445
- Testing
- Povidone-Iodine (PVP-I), Water
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tzu-Ying Huang
Shade Match, Teeth Color
Impact of Presentation Sequence on Patient Tooth Shade Selection
This study is a clinical trial designed to understand how the way a dentist presents tooth color options affects a patient's final choice for their dental treatment.
- Conditions
- Shade Match, Teeth Color, Patient Preference, Aesthetic Perception
- Trial name
- NCT07370545
- Testing
- Sequential Shade Presentation (Natural to Bleached), Sequential Shade Presentation (Bleached to Natural), Simultaneous Shade Presentation (Full Range)
- Where
- Jordan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Fibroids
Misoprostol for Reduction of Blood Loss During Fibroid Surgery
The aim of this research work is to assess the impact of a single preoperative dose of buccal misoprostol in reducing blood loss during abdominal fibroid surgery.
- Trial name
- NCT02209545
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dyslipidemias, Cardiovascular Risk Factor
Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction
Although soy protein has approved health claims in Canada and the US, and is recognized by major cardiovascular clinical practice guidelines for the reduction of cholesterol and risk of coronary heart disease (CHD), these claims…
- Conditions
- Dyslipidemias, Cardiovascular Risk Factor, Dysglycemia
- Trial name
- NCT04861545
- Testing
- Soy
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Maternal Anemia, Micronutrient Deficiency
MMS, IFA, and MMS+IFA Supplementation in Pregnant Women
This study aims to compare the effectiveness of Multiple Micronutrient Supplementation (MMS), Iron-Folic Acid (IFA) supplementation, and combined MMS+IFA supplementation among pregnant women.
- Conditions
- Maternal Anemia, Micronutrient Deficiency, Pregnancy Outcomes, Maternal Nutrition
- Trial name
- NCT07665957
- Testing
- Multiple Micronutrient Supplementation (MMS), Iron-Folic Acid (IFA)
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Child Health and Neonatology
Dengue
A Study of JNJ-64281802 for the Prevention of Dengue Infection
The purpose of this study is to evaluate the prophylactic effect of JNJ-64281802 with respect to the prevention of laboratory-confirmed dengue virus (DENV) infection up to the last day of dosing among participants who have no…
- Trial name
- NCT05201794
- Testing
- JNJ-64281802
- Where
- 38 sites in Brazil, Colombia and 7 more
- Volunteers
- 1,595 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Violence by Teachers
Preventing Violence by Teachers in Primary Schools in Haiti
Violence has severe and long-lasting negative consequences for children's and adolescents' well-being and academic functioning, which can hinder communities' and societies' economic growth.
- Trial name
- ICC-T_HAITI (NCT05081622)
- Testing
- Interaction Competencies with Children - for Teachers (ICC-T)
- Where
- Haiti
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Bielefeld University
Dental Caries
Clinical Performance of a Highly-filled Flowable Composite in Class III Restorations.
The aim of this study was to evaluate the 12-month clinical performance of a highly filled flowable composite resin in anterior teeth.
- Trial name
- NCT07051551
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Gynecologic
Stress Balls in Gynecologic Exams: A Patient Comfort Trial
Women's anxiety about gynecological examinations causes them to skip examinations during this process. Research shows that women with high levels of anxiety are more likely to feel pain.
- Trial name
- NCT06679231
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy
Efficacy of Probiotic Milk Formula on Blood Lipid and Intestinal Function
Probiotic contained milk formula (PMF) intervention for 10 weeks considerably improves gastrointestinal function by modulating fecal movement, intestinal microflora as well as decrease cholesterol and thus help in the management…
- Trial name
- NCT03988153
- Testing
- Probiotic Milk Formula
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
HIV Infections
A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults
This is a phase 1 clinical trial to evaluate the safety, tolerability, and immunogenicity of HIV-1 envelope protein BG505 SOSIP.GT1.1 gp140 trimer Vaccine, Adjuvanted, in up to 48 healthy HIV-uninfected adult volunteers.
- Trial name
- NCT04224701
- Testing
- BG505 SOSIP GT1.1 gp140 Vaccine, Adjuvanted
- Where
- 3 sites in United States, Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Covid19
Evaluation of the Efficacy of Xylitol Nasal Spray Against SARS-CoV-2
The purpose of this study is to assess the efficacy of Xylitol plus Grapefruit Seed Extract (Xlear) nasal spray as an adjunct treatment of COVID-19.
- Trial name
- NCT04610801
- Testing
- Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Larkin Community Hospital
Reproductive Health
A Trial to Determine People's Explicit vs. Implicit Preferences for Gender-inclusive Sexual and Reproductive Health Content
Participants will be shown two different versions of health content and asked which they prefer.
- Trial name
- NCT07601581
- Testing
- Read reproductive health material and review
- Where
- United States
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anxiety
Evaluation of the Effectiveness of New Management Techniques in Reducing Dental Anxiety for Children Undergoing Pulpotomy
The goal of this clinical trial is to reduce dental anxiety for sixety six children undergoing pulpotomy in primary molars by using kaleidoscope glasses and Tell-Show-Play-Doh techniques and evaluation of behavior and anxiety…
- Trial name
- NCT06673030
- Testing
- Using Kaleidoscope glasses during pulpotomy procedures, The Play-Doh Doctor Drill 'n Fill toy set, Group 1 (Tell-Show-Do)
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Mental Health, Resilience
RISE for Nurse Preceptors
The purpose of this study is to determine whether RISE for Nurse Preceptors has a significant impact on nurse preceptors' burnout, resilience, insight, self-compassion, and empowerment, as well as mental well-being, in their…
- Conditions
- Mental Health, Resilience, Self-Compassion, Empowerment
- Trial name
- NCT06822777
- Testing
- RISE for Nurse Preceptors Program
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- AdventHealth
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