Clinical trials: Randomized-controlled Trial
Obesity
Effect of Low-calorie Diet and Orange Juice on Body Weight and Metabolic Parameters of Obese Subjects
This study aimed to verify if combination of a low calorie diet and orange juice consumption results in weight loss and ameliorates metabolic obesity-related biomarkers.
- Trial name
- LCD-OJ-OBESE (NCT02914249)
- Testing
- Orange juice (500 mL/d)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Stress, Emotional
Resilience Curriculum for Novice Physicians-in-training
To determine the feasibility of delivering a structured resilience curriculum to novice physicians-in-training, we propose a pilot study to evaluate recruitment rates, course attendance and compliance with follow-up surveys.
- Trial name
- NCT04977726
- Testing
- STRIVE curriculum
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy
Effects of Mineral Water Consumption on Serum Lipid Parameters
The purpose of the study is to determine the effect of a specific mineral water on serum lipid concentrations in healthy subjects.
- Trial name
- NCT00812617
- Testing
- Mineral water (Hita, Oita, Japan), Mineral water (Aso-gun, Kumamoto, Japan)
- Where
- Japan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Pain, Acute
Intrathecal Nalbuphine is a Comparable Safer Alternative to Fentanyl for Intraoperative Pain Management During Uterine Exteriorization
In case of cesarean section (CS) delivery, spinal anesthesia is the best anesthetic choice. It is simple to perform with rapid onset of anesthesia and lower incidence of failed block.
- Trial name
- NCT04689217
- Testing
- intrathecal drug injection
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction
Physics Forceps vs Conventional Forceps in Extraction of Mandibular Molars
Our study compared two different forceps for extraction of mandibular molars, the conventional extraction forceps and the Physics forceps.
- Trial name
- NCT04875650
- Testing
- Extraction of Mandibular Molar using Physics Forceps, Extraction of Mandibular Molar using Conventional Forceps
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Neurologic Deficits
NeuroVision vs Standard Neuromonitoring
The purpose of this study is to perform a prospective, randomized, controlled clinical trial to assess the utility of IONM in patients undergoing primary, single or multilevel lateral spinal procedures.
- Trial name
- NCT04639297
- Testing
- NeuroVision® IONM, Hospital Based IONM
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This study is an 8-week single center, randomized, double-blind, placebo-controlled, flexible titration trial evaluating the efficacy of solriamfetol in the treatment of fatigue symptoms in adult patients with chronic fatigue…
- Trial name
- NCT04622293
- Testing
- Solriamfetol Oral Tablet [Sunosi]
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Drug Use
The Impact of Alternative Social Assistance Disbursement on Drug-related Harm
This study evaluates whether altering the timing and frequency of social assistance disbursement reduces drug related-harms that increase on the days surrounding monthly synchronized government social assistance cheque issue.
- Trial name
- TASA (NCT02457949)
- Testing
- Non-synchronized social assistance receipt, cheque divided into two equal disbursements
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depression, Social Anxiety
Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety Among Youth
This randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of a mobile-based psychoeducation program (OkeyMind) in mitigating symptoms associated with social anxiety among youth.
- Trial name
- NCT06490315
- Testing
- OkeyMind intervention, Wait-list control
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hong Kong Shue Yan University
Knee Ligament Injury, Anterior Cruciate Ligament Injuries
Functional Outcomes of a Criterion-based Rehabilitation Protocol for ACL Reconstruction in Amateur Athlete
Although current rehabilitation protocols following anterior cruciate ligament reconstruction (ACLR) are based on the graft remodeling process, there is uncertainty about its time schedule.
- Trial name
- NCT05719974
- Testing
- rehabilitation protocol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Out-of-hospital Cardiac Arrest
The PulsePoint Randomized Controlled Trial
"Sudden cardiac arrest" occurs when someone's heart stops beating unexpectedly. Each year, more than 45,000 Canadians have a cardiac arrest.
- Trial name
- NCT01746290
- Testing
- PulsePoint notification
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Obesity
The Safety and Efficacy of vBloc Therapy Delivered by the Maestro Rechargeable System for the Treatment of Obesity
The study evaluated the safety and efficacy of the vBloc Therapy delivered by the Maestro Rechargeable System compared to a sham control for the treatment obesity.
- Trial name
- ReCharge (NCT01327976)
- Testing
- vBloc (Active Device)
- Where
- 10 sites in United States, Australia
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- ReShape Lifesciences
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pressure Ulcer (PU), Pressure Injury Prevention
Effect of a Risk-Based Perioperative Pressure Injury Prevention Bundle in Elective Surgery Patients
This study evaluates whether a risk-based perioperative pressure injury prevention bundle reduces the development of pressure injuries in patients undergoing elective surgery lasting 3 hours or longer.
- Conditions
- Pressure Ulcer (PU), Pressure Injury Prevention, Perioperative Care, Braden Scale
- Trial name
- RiPPB (NCT07725068)
- Testing
- Risk-Based Perioperative Pressure Injury Prevention Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Family Witnessed Resuscitation, Empathy Education
VIDEO LEARNING FOR EMPATHY, ETHICS AND FAMILY WITNESSED RESUSCITATION
This clinical trial (randomized controlled experimental study) aims to learn about the effects of presenting the family-witnessed CPR process from a patient's perspective through 360° virtual reality and 2D video within…
- Conditions
- Family Witnessed Resuscitation, Empathy Education, Ethics Nursing, Education Nursing
- Trial name
- NCT07692568
- Testing
- 360 Degree Virtual Reality Video, 2D Standard Video
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Breastfeeding
Effect of Pilates Exercises on Forward Head Posture in Breastfeeding Women
Musculoskeletal postural issues stemming from infant care positions can exert a significant impact on the cervical, thoracic, and lumbar spine.
- Trial name
- NCT06271850
- Testing
- Ergonomics breastfeeding training, Pilates exercises
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University
Behavior Disorders
Teachers and Parents as Partners During Middle School RCT
There are two aims of this study (a) to examine the effect of Teachers and Parents as Partners on student, parent, and teacher outcomes in middle school and (b) identify barriers and facilitators to implementing Teachers and…
- Trial name
- NCT03614026
- Testing
- Teachers and Parents as Partners
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Primary Burning Mouth Syndrome (BMS)
Theravex® for Burning Mouth Syndrome
In this randomized, double-blind, placebo-controlled trial, 116 adults with primary BMS were assigned (1:1) to receive THERAVEX® Total Oral Care Plus or placebo for 8 weeks.
- Trial name
- NCT07564843
- Testing
- THERAVEX® Total Oral Care Plus
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Diabetes Mellitus, Type 2
Learning Modality in Individuals With Diabetes Incompatible
This study was planned to examine the effect of education based on learning styles in diabetic individuals who are incompatible with treatment, on treatment compliance and metabolic goals.
- Trial name
- NCT05007197
- Testing
- The Effect of Diabetes Education Based on Learning Modality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Pneumococcal Infections
A Phase 1, Randomized, Controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Healthy Adults Aged 18 to 49 Years
This is a Phase 1 first-in-human, randomized, controlled, observer-blinded study with a 2-arm parallel design. Healthy adults aged 18 to 49 years of age with no history of pneumococcal vaccination will be randomized equally to…
- Trial name
- NCT02955160
- Testing
- Multivalent, Tdap
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pfizer
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