Clinical trials: Randomized-controlled Trial
Osteo Arthritis Knee
Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis:
The overall goal of this pilot randomized trial is to obtain necessary prerequisite data to conduct a randomized controlled intervention to test the effect of vitamin K supplementation on knee osteoarthritis progression and…
- Trial name
- NCT05505552
- Testing
- Vitamin K
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- Tufts University
Infertility
An Randomized Double Blind Controlled Trial of niPGT-A in Women With RPL
Objectives: To compare the efficacy in embryo selection based on morphology alone compared to morphology and non-invasive preimplantation genetic testing for aneuploidy (niPGT-A) in women with recurrent pregnancy loss (RPL)…
- Trial name
- niPGTA (NCT05685147)
- Testing
- Non-invasive Preimplantation genetic testing for aneuploidy status
- Where
- Hong Kong
- Volunteers
- 152 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Brain Injuries
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
- Trial name
- NCT04499755
- Testing
- Nucleo CMP Forte
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sherief Abd-Elsalam
Renal Stone, Ureter Stone
Comparison Between 6Fr Vs 4Fr Double J Stent
Double J (DJ) Stenting is a commonly done procedure in endourology to ensure ureteric patency following Urological Interventions. DJ stents are available in various sizes.
- Trial name
- NCT05725226
- Testing
- Double J Stent 6Fr x 26cms, Double J Stent 4Fr x26cms
- Where
- Nepal
- Volunteers
- 110 people
- Sponsor
- Tribhuvan University, Nepal
Crohn's Disease, Ulcerative Colitis
Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD)
This study aims to test the hypothesis that the accelerated infusion of infliximab is not inferior to the conventional 2 hour infusion with respect to the frequency of infusion reaction.
- Trial name
- NCT01346826
- Testing
- Standard 2 hours-infusion, Accelerated 1 hour-infusion, Accelerated 30 minutes-infusion
- Where
- South Korea
- Volunteers
- 145 people
- Sponsor
- Asan Medical Center
Non-small-cell Lung Cancer
Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer
Objective to compare the efficacy and safety of TQB2450 injection combined with anlotinib and chemotherapy, and TQB2450 injection combined with chemotherapy in the treatment of advanced non-small cell lung cancer subjects who…
- Trial name
- NCT06141226
- Testing
- TQB2450 +Anlotinib+Docetaxel
- Where
- 5 sites in China
- Volunteers
- 148 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Healthy Volunteers
A Study of Multiple Ascending Doses of GSBR-1290 in Japanese and Non-Japanese Healthy Participants
The purpose of this study is to assess safety and tolerability of multiple oral doses of GSBR-1290 (capsule) in healthy adult Japanese participants compared to non-Japanese participants.
- Trial name
- NCT05893043
- Testing
- GSBR-1290
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Diabetes Mellitus, Type 2, Inflammation
Randomized Crossover Study of Magnesium Supplementation
The investigators recent epidemiologic work in several national surveys and cohorts of men and women have shown that dietary patterns high in plant-based foods and phytochemicals are associated with lower plasma levels of…
- Trial name
- NCT00737815
- Testing
- Magnesium Citrate: a total of 500 mg elemental magnesium
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pregnancy Complications
Effect of Combined Program of Electro Acupuncture With Exercise on Symphysis Pubis Dysfunction During Pregnancy
Study's Objective: this study aimed to discover the effect of combining electroacupuncture with therapeutic exercises on of symphysis pubis dysfunction during pregnancy.A prospective randomized controlled trial that compared 2…
- Trial name
- NCT07719335
- Testing
- Electro-acupuncture Technique and Stabilizing Exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Pelvic Organ Prolapse, Incontinence
A Randomized Controlled Trial of Electrical Stimulation to Treat Pelvic Floor Disorder
Female pelvic floor disorders (PFDs) include urinary incontinence,pelvic organ prolapse (POP), and fecal incontinence-which often occur together.
- Trial name
- NCT02185235
- Testing
- Electrical Stimulation, Biofeedback, Pelvic Floor Training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Cutaneous Melanoma, Stage III
The Multicentre Selective Lymphadenectomy Trial - 3
The goal of this clinical trial is to demonstrate that there is no difference (non-inferiorty) in the 2 year recurrence-free survival (RFS) between 2 different surgical approaches for clinical Stage III melanoma.
- Trial name
- MSLT-3 (NCT07049276)
- Testing
- Index lymph node resection, Therapeutic lymph node dissection
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,500 people
- Sponsor
- Melanoma Institute Australia
Systemic Sclerosis-Associated PAH
Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is a serious, life-threatening manifestation of systemic sclerosis (SSc), an autoimmune disease of the connective tissue characterized by scarring (fibrosis)…
- Trial name
- NCT01086540
- Testing
- Rituximab, CMRI, prednisone
- Where
- 17 sites in United States
- Volunteers
- 57 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Attendance
Impact of Automated Calls on Pediatric Patient Attendance in Chile
Missed health care appointments present a serious challenge to patient care. Especially in government funded health systems like that of Chile, missed appointments can lead to delayed care, wasted resources, and escalating costs.
- Trial name
- Health Call (NCT02442089)
- Testing
- Health Call
- Where
- Chile
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Major Depressive Disorder (MDD), Borderline Personality Disorders
Home-Based tDCS for Depression in BPD
The present study aims to assess the feasibility of home-based tDCS in remote and urban areas (primary objective). The secondary aim is to obtain a preliminary assessment of the efficacy of 14 home-based tDCS sessions in reducing…
- Trial name
- TENTADIS (NCT06972368)
- Testing
- tDCS, Treatment as Usual (TAU), Psychoeducation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Influenza, Human, Influenza a
Phase I Clinical Trial of Quadrivalent Influenza Virus Split Vaccine
This is a randomized, blinded, active-controlled phase I clinical trial to evaluate the safety and preliminary immunogenicity of the Quadrivalent Influenza Virus Split Vaccine (QIV) in subjects (aged 3 years and above).
- Conditions
- Influenza, Human, Influenza a, Influenza Type B, Influenza Viral Infections
- Trial name
- NCT06622590
- Testing
- QIV, QIV control
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
COVID-19 Respiratory Infection
Role of Vit-D Supplementation on BioNTech, Pfizer Vaccine Side Effect and Immunoglobulin G Response
The goal of this clinical trial study is to investigate the role of anthropometric indices and Vit-D supplementation on BioNTech, Pfizer vaccine side effect and immunoglobulin G response against SARS-CoV-2 in individuals infected…
- Trial name
- NCT05851313
- Testing
- Vitamin-D
- Where
- Iraq
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sulaimani Polytechnic University
Mammary Gland Hyperplasia
Clinical Trial of Ruxian Zengsheng No. 1 Decoction
A prospective, open, randomized, controlled phase II clinical study is planned to clarify the efficacy and related adverse reactions of Mammary Glandular Hyperplasia No.
- Trial name
- NCT04767620
- Testing
- Rugdenzengsheng No. 1 prescription
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Jiuda Zhao
Fatigue, Malignant Ovarian Mixed Epithelial Tumor
Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy
This randomized phase III trial studies how well acetyl-L-carnitine hydrochloride works compared to a placebo in preventing peripheral neuropathy in patients with recurrent ovarian epithelial cancer, primary peritoneal cancer, or…
- Conditions
- Fatigue, Malignant Ovarian Mixed Epithelial Tumor, Neuropathy, Neurotoxicity Syndrome
- Trial name
- NCT01492920
- Testing
- Acetyl-L-Carnitine Hydrochloride, Questionnaire Administration, Quality-of-Life Assessment
- Sponsor
- Gynecologic Oncology Group
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.