Clinical trials: Randomized-controlled Trial
Knee Osteoarthritis, Visual Rehabilitation
Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis
This study aims to investigate the effects of visual rehabilitation and vestibular rehabilitation added to conventional physiotherapy on postural stability, pain, and functional status in individuals with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Visual Rehabilitation, Vestibular Rehabilitation, Postural Stability
- Trial name
- NCT07888920
- Testing
- Conventional Physiotherapy, Visual Rehabilitation, Vestibular Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Aydın University
Acute Ischemic Stroke
Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke
This study is designed to determine the efficacy and safety of SHPL-49 intravenous infusion in acute ischemic stroke patients.
- Trial name
- SAIL (NCT07241520)
- Testing
- SHPL-49 Injection
- Where
- China
- Volunteers
- 1,096 people
- Sponsor
- Shanghai Hutchison Pharmaceuticals Limited
Postoperative Pain, Postpartum Anxiety
Acupressure for Pain and Anxiety After Cesarean Section
The goal of this clinical trial is to evaluate whether acupressure combined with standard post-operative modern medical care can reduce pain and anxiety in postpartum women after cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Postpartum Anxiety, Acupressure
- Trial name
- NCT07805720
- Testing
- Acupressure, Standard care
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Intraventricular Hemorrhage
The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Premature Infants
Premature babies can be very sick and have bleeding in the brain. Giving babies more blood before cutting the umbilical cord by delayed cord clamping or umbilical cord milking has been shown to reduce the risk of bleeding in the…
- Trial name
- PREMOD (NCT01866982)
- Testing
- Umbilical Cord Milking, Delayed Cord Clamping
- Where
- 3 sites in United States
- Volunteers
- 197 people
- Sponsor
- Sharp HealthCare
Low Back Pain
Therapeutic Exercise and Education for Low Back Pain
This study will evaluate a new treatment program for patients with ongoing or long-term low back pain who receive care at primary care physiotherapy units.
- Trial name
- NCT07713082
- Testing
- Therapeutic Exercise, Education on the self-management of low back pain, Usual Care
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- University of Valladolid
Evidence of Cholecystectomy
Effect of Preoperative Oral Carbohydrates on Quality of Recovery
Carbohydrate loading is an important component of enhanced recovery pathways. Preoperative carbohydrate treatments have been widely adopted as part of enhanced recovery after surgery (ERAS) or fast-track surgery protocols.
- Trial name
- laparoscopy (NCT02555020)
- Testing
- Allocated to Carbohydrated group, Allocated to MN NPO group,
- Volunteers
- 153 people
- Sponsor
- Yonsei University
Ischemic Preconditioning
Upper Body Ischemic Preconditioning and Judo Performance
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling…
- Trial name
- NCT07912424
- Testing
- Upper-limb ischemic preconditioning
- Where
- Kazakhstan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Pain, Comfort
Virtual Reality Intervention in Children After Hypospadias Surgery
The aim of this study is to examine the effect of virtual reality glasses use on pain, comfort, and psychosocial symptoms in children after hypospadias surgery.
- Conditions
- Pain, Comfort, Psychosocial Symptoms
- Trial name
- NCT07752680
- Testing
- Virtual reality headset, routine clinical practice
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medipol University Hospital
Depression, Anxiety, Anger
Advancing Family Wellbeing Through a Massive Open Online Intervention: The LightBEAM Program
Early childhood is a critical period for developmental outcomes, and the parent-child relationship plays a vital role in shaping cognitive and social development.
- Conditions
- Depression, Anxiety, Anger, Parenting, Stress Psychological
- Trial name
- NCT07026838
- Testing
- The Light Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- University of Manitoba
Digestive System Disease, Urologic Diseases
Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
The aim of this multicenter, prospective, randomized, double-blind and large sample study is to explore the preventive effect of low-dose droperidol on POD in elderly patients after non-cardiac surgery, providing new approach for…
- Conditions
- Digestive System Disease, Urologic Diseases, Gynecological Disease, Orthopedic Surgery
- Trial name
- NCT05401058
- Testing
- Droperidol Injection, Saline
- Where
- 9 sites in China
- Volunteers
- 797 people
- Sponsor
- RenJi Hospital
Obstructive Sleep Apnea, Obesity
Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery
The investigators propose to compare two different treatments, continuous positive airway pressure (CPAP) versus breathing of atmospheric pressure, in subjects with obstructive sleep apnea (OSA)recovering from weight loss surgery…
- Trial name
- NCT01697878
- Testing
- CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
Transcutaneous Electrical Nerve Stimulation in Relation to Central Sensitization in Osteoarthritis of the Knee
Background Central sensitization has recently been documented in patients with knee osteoarthritis. So far, the presence of central sensitization has not been considered as a confounding factor in studies assessing the pain…
- Trial name
- TENSSENS (NCT01390285)
- Testing
- Transcutaneous electric nerve stimulation
- Volunteers
- 98 people
- Sponsor
- Vrije Universiteit Brussel
Osteoarthritis, Knee
Determining the Effectiveness of a New Phototherapy Treatment for the Knee Osteoarthritis
Light therapy (phototherapy) has previously been shown to help reduce pain for people with musculoskeletal pain conditions, such as knee osteoarthritis (OA).
- Trial name
- NCT04234685
- Testing
- High Intensity Physio Light Therapy (HIPL Therapy™), Education, Aerobic Exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Jordan Miller, PT, PhD
Traumatic Brain Injury, Upper Extremity
Transcutaneous Auricular Vagus Nerve Stimulation to Improve Upper Extremity Recovery After Traumatic Brain Injury
Upper extremity weakness, impaired coordination, reduced dexterity, and limited arm and hand use may continue after TBI. Repetitive, task-specific rehabilitation may improve function, but recovery can remain incomplete.
- Trial name
- taVNS (NCT07867015)
- Testing
- taVNS, FTP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Hospital
Stage Ib Lung Carcinoma
Multicenter Randomized Controlled Trial Adjuvant Chemotherapy vs Observation in pStage Ib Lung Adenocarcinoma
Researchers developed the nomogram which evaluate the risk of recurrence after surgical resection, and found that the stage 1 NSCLC patients with more than 104 point of nomogram showed similar recurrence rate to the recurrence…
- Trial name
- NCT02281708
- Testing
- vinorelbine plus cisplatin
- Where
- South Korea
- Volunteers
- 1,012 people
- Sponsor
- Seoul National University Hospital
Alzheimer's Disease
Safety Study of Passive Immunization for Patients With Mild to Moderate Alzheimer's Disease
This research study will assess whether AAB-001 is safe, well tolerated and effective for use in patients with Alzheimer's Disease. AAB-001 is a new drug that is not available outside this study.
- Trial name
- NCT00174525
- Testing
- AAB-001
- Where
- 2 sites in United States
- Sponsor
- Pharmacology Research Institute
Gastrointestinal Cancer, Prehabilitation
Prehabilitation to Improve Cancer Surgery Outcomes
This is a randomized control trial aiming to investigate the use of a prehabilitation regimen for patients undergoing major GI cancer surgery and its effects on measurements of HRQOL, LOS, and post-operative complications.
- Conditions
- Gastrointestinal Cancer, Prehabilitation, Surgery, Physical Activity
- Trial name
- PICaSO (NCT03502317)
- Testing
- Physical Prehabilitation, Psychological Prehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 128 people
- Sponsor
- Mount Sinai Hospital, Canada
Colic
Human Milk Oligosaccharide (HMO) Supplementation in Colic Management
Efficacy and tolerability of a composition comprising of HMO in a supplement format on colic management: a double-blind, randomized, placebo-controlled trial
- Trial name
- NCT05554991
- Testing
- HMO, Parental reassurance and support
- Where
- 7 sites in Italy, Spain
- Volunteers
- 5 people
- Sponsor
- Société des Produits Nestlé (SPN)
Catheterization, Central Venous
Central Line Catheterization With Flexible Tip Straight Guidewire in Small Children
The purpose of this study is to compare the differences in central venous catheter insertion time, success rate, and complication between the flexible tip straight guidewire and J-tip guidewire for ultrasound-guided central…
- Trial name
- NCT03530618
- Testing
- Flexible tip straight guidewire, J-tip
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Seoul National University Hospital
Atherosclerosis, Coronary Artery Disease
Clinical Trial for Dose Finding and Safety of RVX000222 in Subjects With Stable Coronary Artery Disease
The purpose of this study is to investigate dose range, safety and efficacy of RVX000222 in subjects with stable coronary artery disease.
- Trial name
- ASSERT (NCT01058018)
- Testing
- RVX000222
- Where
- United States
- Volunteers
- 299 people
- Sponsor
- Resverlogix Corp
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