Clinical trials: Rapid Diagnosis
Streptococcal Pharyngitis
Diagnostic Accuracy of Rapid Molecular Tests for Group A Streptococcal Pharyngitis Using Saliva Samples
Observational study evaluating the diagnostic accuracy of rapid point-of-care molecular Group A strep diagnostic tests in saliva as compared to standard culture- and PCR-based techniques for the management of children aged 3-15…
- Trial name
- NCT05521568
- Testing
- Index test: Abbott ID NOW STREP A 2, Reference standard test: Composite of culture and PCR-based tests based on a throat swab, Comparator test: Rapid antigen detection test (usual care)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Glaucoma, Primary Open Angle Glaucoma
Development and Validation of a Model to Predict Fast Progression in Glaucoma
1. The purpose of this study is to obtain genetic data on a well-defined population of patients with glaucoma that had accurate measurements of rates of structural and functional change over time. 2.
- Conditions
- Glaucoma, Primary Open Angle Glaucoma, Glaucoma, Suspect
- Trial name
- NCT04454190
- Testing
- Collection of genetic material
- Where
- United States
- Volunteers
- 1,152 people
- Sponsor
- Duke University
Circumcision Adult, HIV CDC Category B2
Evaluation of Safety and Efficacy of the PrePexTM Device for Rapid Scale up of Adult MC Programs in Zimbabwe
The protocol, approved by the Medical Research Council, was issued to assess the safety and efficacy of the non-surgical device for applying it to the national scale up of adult male circumcision in Zimbabwe
- Conditions
- Circumcision Adult, HIV CDC Category B2, HIV Infections
- Trial name
- ZW-01 (NCT01956396)
- Testing
- PrePex™ device
- Where
- Zimbabwe
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Child Welfare, Zimbabwe
Type 2 Diabetes Mellitus
Comparison of SAR342434 to Humalog as the Rapid Acting Insulin in Adult Patients With Type 2 Diabetes Mellitus Also Using Insulin Glargine
Primary Objective: To demonstrate non-inferiority of SAR342434 versus Humalog in glycated hemoglobin A1c (HbA1c) change from baseline to Week 26 in participants with type 2 diabetes mellitus (T2DM) also using insulin glargine.
- Trial name
- SORELLA2 (NCT02294474)
- Testing
- SAR342434, Humalog, insulin glargine HOE901
- Where
- 103 sites in United States, Argentina and 10 more
- Volunteers
- 505 people
- Sponsor
- Sanofi
Correlation of cFDNA During CPB to Laboratories SIRS Parameters and Clinical Outcomes
Measurement of Circulating Cell-free DNA (cfDNA) for Diagnosis and Prognosis of Various Diseases and Evaluation of Tissue Damage
To characterize the changes in circulating cell-free DNA (cfDNA) levels during cardiopulmonary bypass (CPB) and to access their association with outcomes compared to standard scores.
- Trial name
- NCT05094960
- Testing
- Blood samples
- Volunteers
- 71 people
- Sponsor
- Soroka University Medical Center
Gingivitis, Gingival Diseases
NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery
The aim of this study is to prove that Novosyn Quick and Monosyn Quick are equivalent in early wound healing in adult patients undergoing resective periodontal surgery.
- Conditions
- Gingivitis, Gingival Diseases, Periodontal Diseases
- Trial name
- NOQMOQS (NCT05813236)
- Testing
- Novosyn® in resective periodontal surgery, Monosyn® in resective periodontal surgery
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Aesculap AG
Covid19
Study Utilizing BIOZEK COVID-19 Antigen Rapid Test.
This is a research study to evaluate the Sensitivity and Specificity of BIOZEK COVID-19 Antigen Rapid Test on samples collected by a healthcare professional versus self-collection; and to perform analysis to compare results.
- Trial name
- NCT04805892
- Testing
- BIOZEK COVID-19 Antigen Rapid Test
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Mach-E B.V.
Obesity
Effects of Advertising on Young Children's Perception of Taste
To test whether young children's actual taste preferences are influenced by the natural marketing environment in which they live.
- Trial name
- NCT00185536
- Testing
- Packaging and identification of source
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
COVID-19
Bioaerosol Sampling Device (BSD) Clinical Study
The goal of this clinical trial is to learn about the bioaerosol sampling device (BSD) and how it can sample patient bioaerosols (breath) and patient's nares for the detection of COVID-19 viral particles in patients seeking to be…
- Trial name
- NCT06047067
- Where
- 6 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Cantor BioConnect, Inc.
Coronary Artery Disease, Myocardial Infarction
Personalization of Long-Term Antiplatelet Therapy - RAPID EXTEND
In patients after myocardial infarction (MI) (heart attacks) and treated with percutaneous coronary intervention (PCI), the current standard is dual antiplatelet therapy (DAPT), with aspirin and a P2Y12 receptor inhibitor, for 1…
- Trial name
- RAPID EXTEND (NCT03729401)
- Testing
- Active Comparator: Dual Antiplatelet Therapy (DAPT) - Aspirin 81 mg + Ticagrelor 60mg twice daily, Ticagrelor Monotherapy: Ticagrelor 60 mg twice daily, Personalized Therapy Arm: Aspirin 81 mg or Ticagrelor 60mg twice daily or Clopidogrel 75 mg once daily
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Arrhythmias
HIPACE High Frequency Low Energy Pacing to Terminate Fast Ventricular Arrythmias
People that have survived, or are at high risk of a lifethreatening ventricular arrhythmia are routinely offered a defibrillator (ICD).
- Trial name
- HIPACE (NCT02629445)
- Testing
- Cardiac Resynchronisation Defibrillator
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
ANCA Associated Vasculitis, Rapidly Progressive Glomerulonephritis
A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO Trial
The RENATO trial is a multicenter randomized controlled trial that evaluates the efficacy of pioglitazone to improve renal outcomes in ANCA-associated vasculitis.
- Conditions
- ANCA Associated Vasculitis, Rapidly Progressive Glomerulonephritis, Crescentic Glomerulonephritis
- Trial name
- RENATO (NCT05946564)
- Testing
- Pioglitazone (ACTOS®)
- Where
- 25 sites in France
- Volunteers
- 126 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes Mellitus
Development of a Fast Measurement Technique of Insulin Resistance in Human
Insulin resistance, characterised by a depressed cellular sensitivity to insulin in insulin-sensitive organs, is a central feature of the metabolic syndrome.
- Trial name
- GLUCIMAG (NCT01493934)
- Testing
- injection of 6-DIG
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Prostate Cancer
Improved Prostate Cancer Diagnosis - Combination of Rapid Prebiopsy Magnetic Resonance Imaging and Biomarkers
This study will enroll 200 men with clinical suspicion of prostate cancer due to higher serum level of PSA than 2.5 ng/ml or abnormal digital rectal examination.
- Trial name
- IMPROD2_0 (NCT02844829)
- Testing
- Prostate MRI
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Rheumatoid Arthritis
Assessment of the Safety of Adalimumab in Rheumatoid Arthritis Patients Showing Rapid Progression of Structural Damage of the Joints, Who Have no Prior History of Treatment With Disease-modifying Anti-rheumatic Drugs or Biological Agents
This study was conducted to examine the safety profile and the effectiveness in daily clinical practice of adalimumab in rheumatoid arthritis participants showing rapid progression of structural damage of the joints, who had no…
- Trial name
- NCT01783730
- Volunteers
- 163 people
- Sponsor
- AbbVie
Anxiety Disorders
FASTMAS (Fast-Fail Trials in Mood and Anxiety Spectrum Disorders) Kappa Opioid Receptor Phase 1 Study
The available treatments for patients with mood and anxiety spectrum disorders have significant limitations. This study will contribute significantly to public health by taking steps to address these limitations by aiding in the…
- Trial name
- KOR1 (NCT02218775)
- Testing
- LY2456302
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Andrew Krystal
Genetic Disease, Genetic Syndrome
Utility of Rapid Whole Genome Sequencing in the NICU: A Pilot Study
This is a pilot study involving a prospective group of 15 evaluable patients who will undergo rapid whole genome sequencing in addition to standard of care testing.
- Trial name
- NCT03918707
- Testing
- Rapid Whole Genome Sequencing (rWGS)
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Alzheimer Disease
REXULTI General Use Results Survey in Patients With Hyperactivity, or Aggressive Behavior Associated With Alzheimer's Dementia
The purpose of this study is to evaluate safety of REXULTI in patients under daily clinical settings. In addition, information on efficacy will be collected.
- Trial name
- NCT06875986
- Testing
- Brexpiprazole (Rexulti)
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Opioid Overdose
Opioid Rapid Response System: Naloxone Training in Communities
The pervasive impact of the opioid epidemic has touched all layers of society for the past two decades, resulting in over 115 deaths daily and imposing annual costs of $78.5 billion.
- Trial name
- NCT06238128
- Testing
- Opioid Rapid Resonse System (ORRS) training, Non-active opioid overdose response training
- Where
- United States
- Volunteers
- 773 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Diabetes Mellitus, Type 1
Evaluation of Fiasp® (Fast Acting Insulin Aspart) in 670G Hybrid Closed-Loop Therapy
This is a pilot outpatient study conducted at Stanford to obtain preliminary data on how Fiasp® works in a closed-loop system and to determine if any changes need to be made to the 670G pump to optimize the use of Fiasp®.
- Trial name
- NCT03554486
- Testing
- Fiasp, Novolog
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Stanford University
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