Clinical trials: Reconstruction
Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction.
- Trial name
- NCT02664545
- Testing
- BEAR Scaffold, Tendon Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miach Orthopaedics
Breast Augmentation, Breast Reconstruction
CPG Styles Study: A Study of the Safety of the Contour Profile Gel Breast Implants (CPG Styles Study)
The CPG Styles Study is designed to demonstrate the safety of different styles of Mentor's Contour Profile Gel (CPG) breast implants in women who are undergoing primary augmentation, primary reconstruction, or revision.
- Conditions
- Breast Augmentation, Breast Reconstruction, Breast Revision
- Trial name
- NCT01959880
- Testing
- The Contour Profile Gel (CPG) breast implants
- Where
- United States
- Volunteers
- 1,891 people, healthy volunteers welcome
- Sponsor
- Mentor Worldwide, LLC
Pelvic Organ Prolapse, Normal Pelvic Floor
The 3D Reconstruction Research of Pelvic Organ Prolapse Disease
Female pelvic organ prolapse (FPOP) is one of the main diseases affecting the quality of life of middle aged and elderly women in non-neoplastic diseases.
- Trial name
- NCT03146195
- Testing
- Dynamic Magnetic resonance imaging
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Safety and Performance, Breast Tissue Expander
Post-marketing Clinical Monitoring of Safety and Performance of Breast Tissue Expander for Breast Reconstruction
The study investigates the safety and performance of Silimed® brand breast tissue expander in women born with indication for breast reconstruction.
- Trial name
- STEPS-R (NCT06981481)
- Testing
- Breast tissue expander
- Where
- 3 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Alveolar Cleft
Alveolar Cleft Grafting by Double Iliac Bone Blocks Versus Iliac Spongy Bone From Anterior Iliac Crest
Reconstruction of Alveolar Cleft Using Double Iliac Corticocancellous Blocks in comparison with the gold standard technique ( cancellous bone ) both from anterior iliac crest.
- Trial name
- NCT05283005
- Testing
- Grafting of the alveolar cleft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
ACL Injury, Rehabilitation After ACL Reconstruction
Functional Outcomes of an Accelerated Rehabilitation Protocol for ACL Reconstruction in Amateur Athletes
The main goal of a rehabilitation program after an ACL reconstruction is to regain mobility and muscle function and ultimately to return to sports participation.
- Conditions
- ACL Injury, Rehabilitation After ACL Reconstruction, Accelerated Protocol
- Trial name
- ACL (NCT05716529)
- Testing
- rehabilitation protocol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of Core Exercises on Balance in People With and Without ACL Surgery
The main purpose of this study is to evaluate and compare the effects of an 8-week core stabilization exercise program on balance, trunk muscle endurance, and lower body strength.
- Trial name
- NCT07328139
- Testing
- Core Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Scar
Comparison of Scar Results and Time for Closures of Scalp Defects Via Pulley Sutures or Layered Repairs
Surgical defects on the scalp require closure via various techniques of suture placement. A traditional technique requires both dermal (deep) and epidermal (superficial) placement of sutures to close the defect; this is referred…
- Trial name
- NCT02744950
- Testing
- Pulley stitches, Intermediate Repair
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Breast Augmentation, Breast Reconstruction
Evaluation of the Safety and Performance of ESTYME® MATRIX Round and Anatomical Breast Implants - EMMIE Study
The study will evaluate the safety and performance of the ESTYME® MATRIX Round and Anatomical Silicone Gel-Filled Breast Implants in the breast augmentation and reconstruction.
- Trial name
- EMMIE (NCT03386682)
- Testing
- ESTYME® MATRIX Breast Implants
- Where
- 8 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Symatese Aesthetics
Nonsuicidal Self Injury, Stigmatization
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and…
- Conditions
- Nonsuicidal Self Injury, Stigmatization, Cicatrix, Skin Transplantations
- Trial name
- NCT04420442
- Testing
- Scar Transformation Group
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Arthritis
Study Comparing SBS and LRTI for Treatment of CMC Arthritis
A multi-center, randomized control trial comparing the two standard of care surgical treatments for CMC arthritis ; trapezial excision with or without soft tissue interposition and /or ligament reconstruction (LRTI) versus the…
- Trial name
- SBSvsLRTI (NCT05111405)
- Testing
- CMC Arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Fraser Orthopaedic Research Society
Ankle Injuries
Sural Flap and Anterolateral Thigh Flap in Tissue Reconstruction Around the Ankle
The aim of the study is to evaluate the outcomes of coverage of soft tissue defects of leg and foot by modified sural flap versus anterolateral thigh flap
- Trial name
- NCT04906967
- Testing
- flaps
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Temporomandibular Joint
Tempromandibular Joint Reconstruction Via Computer-Assisted Surgery Simulation
This study was planned to evaluate the accuracy of virtual surgical planning and three-dimensional (3D) printed templates in reconstruction of temporomandibular joint (TMJ) with costochondral graft.
- Trial name
- NCT06811415
- Testing
- virtual temporomandibular joint reconstruction with costochondral graft
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Tanta University
Papilla Reconstruction
Modified Pedicle Subepithelial Connective Tissue Graft for Interdental Papillary Reconstruction Around Delayed Implants in the Esthetic Zone: A Case Series Trail
This case series trial aims to evaluate the effect of a modified pedicle subepithelial connective tissue graft in creating anatomical papilla around one-stage delayed implant in the esthetic zone to establish better esthetics.
- Trial name
- delay implant (NCT04843826)
- Testing
- papilla reconstruction
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ahmed Sadek Mohamed
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Tetralogy of Fallot
Role of 3D Echocardiography Knowledge-based Reconstruction in ACHD
The main objective of this study is to evaluate the reproducibility and accuracy of TTE-3DKBR in assessing RV volume and EF compared to the reference method of CMR in a group of ACHD patients with known moderate or severe PR…
- Trial name
- NCT06282926
- Testing
- Echocardiography assessment
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gingival Papillary Cratering
Efficacy of HA Gel Injection Versus Multilayer (L-PRF) in the Interdental Papilla Reconstruction
This research aims to investigate the effectiveness of non invasive application Hyaluronic acid gel injection versus minimally invasive surgical approach using multilayer L-PRF both clinically and radiographically as a suitable…
- Trial name
- NCT05953896
- Testing
- Hyaluronic acid gel, Multilayer L-PRF membranes
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aya Elleithy
Anterior Cruciate Ligament Rupture, Electroencephalography
Functional Connectivity After Anterior Cruciate Ligament Reconstruction
Background: Despite surgical reconstruction and rehabilitation, individuals after a primary anterior cruciate ligament injury have a significantly increased risk of relapse.
- Conditions
- Anterior Cruciate Ligament Rupture, Electroencephalography, Injuries
- Trial name
- FCACLR (NCT05487768)
- Testing
- EEG measurement
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Bone Augmentation
Reconstruction of Deficient Maxillary Ridges Using Retromolar Blocks With and Without Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT06900933
- Testing
- Onlay bone block covered with collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ventral Hernia, Incisional Hernia
The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
This is a prospective cohort study. Patients have an incisional or parastomal hernia with >20 cm fascial defect on pre-operative imaging who will undergo an anticipated open bilateral transversus abdominis release with…
- Conditions
- Ventral Hernia, Incisional Hernia, Parastomal Hernia
- Trial name
- NCT06575166
- Testing
- Abdominal wall tension, Intra-abdominal pressure
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic