Clinical trials: Recovery of Postoperative
Femoral Neck Disease
A Study of Ropivacaine Combined With Different Concentrations of Methylene Blue Fascia Iliaca Block in Postoperative Analgesia, Cognition, and Hip Function Recovery in Patients Undergoing Hip Arthroplasty
Total hip arthroplasty (THA) is a commonly used treatment for hip lesions, but it is often accompanied by persistent pain after surgery, which obviously affects the quality of life of patients, so perfect postoperative analgesia…
- Trial name
- NCT06520306
- Testing
- Ropivacaine combined with methylene blue for iliac fascia block
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Wang wanxia
Stomach Neoplasms
Enhanced Recovery After Surgery (ERAS) on Laparoscopy-assisted Distal Gastrectomy
This study evaluates the safety and effectiveness of enhanced recovery after surgery(ERAS) on laparoscopic distal gastrectomy for gastric cancer.All of participants received an ERAS program.
- Trial name
- NCT03016026
- Testing
- ERAS
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Anesthesia, Anesthesia Complication
Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot Trial
Up to 40% of patients experience suboptimal recovery in the days following major surgery, limiting their return to functional independence.
- Conditions
- Anesthesia, Anesthesia Complication, Surgery, Quality of Life
- Trial name
- OPUS (NCT06884540)
- Testing
- Dexmedetomidine, lidocaine, control group
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- CHU de Quebec-Universite Laval
Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder
The Role of Neuroinflammation on Neurocognitive Outcome in Cardiac Surgery
RATIONALE: Postoperative cognitive changes are common after cardiac surgery and can be categorised into three main types: postoperative delirium (POD), delayed neurocognitive recovery (DNCR) and postoperative neurocognitive…
- Conditions
- Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder, Cardiac Surgery, Major Surgery Under General Anesthesia
- Trial name
- INOCS (NCT07200726)
- Testing
- Observational study design - no intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Ziekenhuis Oost-Limburg
Sternotomy, Postoperative Delirium
Comparison of the Postoperative Analgesic Effectiveness of Erector Spinae Plane Block Versus Its Combination With Superficial Parasternal Intercostal Plane Block Within the ERACS Program
This prospective, randomized, double-blind, parallel-group clinical trial within the Enhanced Recovery After Cardiac Surgery (ERACS) program compares postoperative analgesic effectiveness of bilateral erector spinae plane (ESP)…
- Conditions
- Sternotomy, Postoperative Delirium, Postoperative Pain Management
- Trial name
- ERACS-ESP-SPIP (NCT07304635)
- Testing
- Procedure: Erector Spinae Plane (ESP) Block, Erector Spinae Plane (ESP) Block + Superficial Parasternal Intercostal Plane (SPIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara University
Rehospitalization
Use of a Smartphone APP for the Management of Postoperative Home Recovery
To calculate the incidence rates of postoperative adverse events (moderate and severe) and rehospitalization in patients undergoing thoracic surgery followed in follow-up using a smartphone application.
- Trial name
- NCT06856317
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Metabolic Acidosis
Intraoperative Cell Salvage and Postoperative Acidosis
Metabolic acidosis is a common complication that patients experience in the early postoperative period following cardiac surgery.
- Trial name
- NCT02800343
- Testing
- routine administration of 0.9% sodium chloride
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- University of Edinburgh
Bladder Cancer, Nutrition Aspect of Cancer
Trimodal Prehabilitation for Cystectomy Patients to Enhance Post-operative Care
Trimodal prehabilitation is a preoperative three-tiered (trimodal) approach to optimizing physical and mental health. It has been found to successfully improve functional recovery in patients undergoing colorectal surgery…
- Trial name
- TPC-RCT (NCT03347045)
- Testing
- Trimodal Prehab & ERP, No Prehab; ERP Alone
- Volunteers
- 50 people
- Sponsor
- Jason Martyn
Total Knee Arthroplasty (Replacement)
A Study on the Physiological Outcomes of the Enhanced Recovery After Surgery Model in Older Adults Undergoing Total Knee Arthroplasty
With the advent of an aging society, the demand for total knee arthroplasty (TKA) continues to increase. Postoperative recovery is influenced not only by the surgical procedure itself but also by pain control, joint function, and…
- Trial name
- NCT07828418
- Testing
- Enhanced Recovery After Surgery (ERAS) Care Pathway, Usual Perioperative Care
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Acupressure, Post-Op Complication
Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section
Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis…
- Conditions
- Acupressure, Post-Op Complication, Cesarean Section, Bowel Ileus
- Trial name
- NCT04620850
- Testing
- Acupressure
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cervical Myelopathy, Ossification of Posterior Longitudinal Ligament in Cervical Region
The Establishment of the Integration of Surgery and Postoperative Intensive Recovery of Patients With CSM
This study aims to establish the specialist consensus of the integration of posterior approach surgical treatment and postoperative intensive recovery management for CSM or OPLL patients, and verify its safety, practicability and…
- Trial name
- NCT04947891
- Testing
- Intensive recovery management
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
Laparoscopic Nephrectomy, Enhanced Recovery After Surgery
Patients Undergoing Laparoscopic Nephrectomy Walk Out From Operating Room After Surgery
Early mobilization is considered as an important strategy to enhance postoperative recovery. However, direct association between very early mobilization and improved recovery needs randomized control trials to prove.
- Trial name
- WOFOR-N1 (NCT03960697)
- Testing
- walk out from operating room
- Where
- 2 sites in China
- Volunteers
- 182 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Complex Congenital Heart Disease, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
This study is a multicenter, stepwise design, cluster randomized controlled trial. Random sequence is generated by computer, and each center enters the intervention expectation (Phase I) in random order to implement ERAS…
- Trial name
- NCT05914103
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,030 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Insulin Resistance, ERAS
Kelulut Honey as an Alternate Source of Carbo-Loading in Abdominal Surgery Involving the Digestive System
The study aims to identify if Kelulut Honey can be a potential alternative for the use of preoperative carboloading instead of the commercially available product, Carborie.
- Trial name
- Kel-Load (NCT04438590)
- Testing
- Kelulut Honey, Carborie
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Osteo Arthritis of the Knee
A Trial of Intraoperative Fibrin Sealant on Postoperative Recovery After Total Knee Replacement
This study is conducted as a pilot trial to assess the added benefit of the VeraSeal fibrin sealant to TXA on postoperative outcomes following TKR.
- Trial name
- NCT07455591
- Testing
- fibrin sealant, Tranexamic Acid (TXA)
- Where
- Singapore
- Volunteers
- 78 people
- Sponsor
- Singapore General Hospital
Pain
Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
This study will determine whether a drug called sodium nitrite helps improve pain and post-operative recovery associated with knee replacement surgery.
- Trial name
- NCT05893160
- Testing
- JAN101 SR
- Sponsor
- University of Alabama at Birmingham
Benign Hysterectomy, Postoperative Recovery
Hysterectomy - A Regional Intervention Study
Approximately 4,000 procedures with hysterectomy for benign indication are performed annually in Sweden. There are large differences in preoperative information, planning of surgery and surgical technique.
- Conditions
- Benign Hysterectomy, Postoperative Recovery, Preoperative Planning
- Trial name
- HYSTERI (NCT05255120)
- Testing
- Intiensified structured perioperative information
- Where
- 2 sites in Sweden
- Volunteers
- 230 people
- Sponsor
- University Hospital, Linkoeping
Ventilatory Depression, Postoperative Respiratory Failure
Hyperoxia on Ventilation During Recovery From General Anesthesia
In this preliminary, crossover investigation the investigators will examine the effect of oxygen supplementation on the recovery of breathing in the immediate post-anesthesia period.
- Trial name
- NCT05922020
- Testing
- Oxygen gas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Enhanced Recovery After Surgery, Spine Surgery
Enhanced Recovery After Spine Surgery
Enhanced recovery pathways (ERP) after surgery have been shown to decrease length of stay and perioperative complications in a range of surgical specialties.
- Trial name
- NCT02949518
- Testing
- Enhanced Recovery Pathway (ERP) for Spine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Sleep Disorder
Association Between Preoperative Insomnia and Postoperative Quality of Recovery : A Prospective Observational Study
Although patients with cancers are prone to insomnia, especially waiting for surgery during hospitalization, and insomnia promotes acute respiratory infections (ARI) and is not conducive to the postoperative quality of recovery…
- Trial name
- PIPQoR (NCT06008873)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
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