Clinical trials: Rectal Fistula
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Anal Fistula
Randomized Control Trial of Micronized Purified Flavonoid Fraction for Post Operative Treatment in Anal Fistula Surgery
The aim of this study is to evaluate the effect of micronized purified flavonoid fraction on postoperative symptoms after surgery of anorectal fistulas.
- Trial name
- NCT06184438
- Testing
- Micronized purified flavonoid fraction(Daflon 1000mg)
- Where
- Taiwan
- Volunteers
- 106 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Perianal Fistula Due to Crohn's Disease, Fistula in Ano
Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease
Objectives: Primary: To demonstrate the safety of allogeneic UC-MSCs administered by injection for complex perianal fistulas in patients with Crohn's disease Secondary: To determine the efficacy of a single/multiple allogeneic…
- Trial name
- NCT05039411
- Testing
- PF2020-CELL (UC-MSCs) - Allogeneic Human Umbilical Cord Mesenchymal Stem Cells
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- CryoCord Sdn Bhd
Anal Fistula
Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Questionnaire) ：A Multi-center Study
The investigators verify the reliability and practicality of the Chinese adaptation results of QoLAF-Q, which helps Chinese doctors better master the methods and techniques of quality of life assessment.
- Trial name
- NCT06962228
- Testing
- Anal fistula surgery
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Wound Healing, Anal Fistula
Platelet- Rich Plasma Injection
This randomized controlled study aims to investigate the effect of injection of platelet rich plasma on the postoperative outcome of perianal wound after anal fistula surgery in terms of healing time, reduction in wound size…
- Trial name
- prp (NCT06887166)
- Testing
- Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anal Fistula, Anal Fissure Chronic
Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions
This study aims to assess the role of Enhanced recovery after surgery(ERAS) protocol in reducing postoperative urine retention (POUR) after surgery for benign anorectal conditions.
- Conditions
- Anal Fistula, Anal Fissure Chronic, Haemorrhoid, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT06803550
- Testing
- Enhanced recovery after surgery protocol, Routine pathway
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Anal Fistula
Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly
The purpose of this open, multicenter pilot trial is to evaluate the tolerance of the combination of a gel and a plug made of Wharton's jelly in the treatment of ano-perineal fistulas resistant to surgical treatment.
- Trial name
- NCT05638139
- Testing
- SygeLIX-F + SygeLIX-G
- Where
- 2 sites in France
- Volunteers
- 9 people
- Sponsor
- TBF Genie Tissulaire
Anal Fistula
Tissue Therapy of Transsphincteric Anal Fistula
This clinical study aims to evaluate the outcome of the treatment of complex perianal fistulas (PAF) by the combination of minimal surgical debridement with regenerative cellular therapeutics.
- Trial name
- REP-PAF (NCT06303752)
- Testing
- ADRC injection, ADRC001 injection
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- University of Southern Denmark
Anal Fistula
Patient's Quality of Life and Functional Changes After Fistula Surgery
This is a prospective observational study that will monitor the effects of surgery for anal fistula on the patient quality of life using many valid questionnaires
- Trial name
- NCT06548724
- Testing
- assessment of quality of life before and after anal surgery
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Crohn Disease, Rectal Fistula
A Study of the Quality of Life in Adults With Crohn's Disease With Complex Perianal Fistulas
The main aim of the study is to assess the quality of life of people with Crohn's disease after treatment for complex perianal fistulas (CPF) in a standard clinic setting.
- Trial name
- CONFLICT (NCT04876690)
- Where
- 5 sites in Portugal
- Volunteers
- 15 people
- Sponsor
- Takeda
Anal Fistula, Complex Perianal Fistulas
Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula
The purpose of this study is to evaluate the distribution and dynamic behavior of Nuclide labeled TH-SC01 cells in vivo in patients with perianal fistula
- Conditions
- Anal Fistula, Complex Perianal Fistulas, Crohn's Disease
- Trial name
- NCT06429241
- Testing
- Mesenchymal Stem Cells (MSCs)
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Anal Fistulas, Anal Fistula
Identifying Landmark Factors of Anal Fistulas
The goal of this observational study is to understand the effects of anatomical factors, etiology, and complexity of anal fistula on the prognosis of patients undergoing anal fistula surgery within one year post-operation.The…
- Trial name
- NCT06421129
- Testing
- anal fistula surgery
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Guanlin Liu
Crohn Disease, Rectal Fistula
A Study Using Artificial Intelligence to Identify Adults With Complex Perianal Fistulas Associated With Crohn's Disease
Natural Language Processing and machine learning are examples of artificial intelligence tools. This study will check if these tools correctly identify people with Crohn's disease with complex perianal fistulas from their medical…
- Trial name
- INTUITION-CPF (NCT04844593)
- Where
- 3 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Takeda
Fistula-in-ano
Collagen Paste vs Mucosal Advancement Flap for FIA
The treatment for fistula-in-ano (FIA) remains a challenge to General and Colorectal Surgeons Worldwide. A variety of surgical treatments have been described for high anal fistulas, but none offers the panacea of fistula…
- Trial name
- NCT06386835
- Testing
- Collagen Paste, Mucosal advancement
- Where
- 2 sites in Hong Kong
- Volunteers
- 118 people
- Sponsor
- Chinese University of Hong Kong
Fistula in Ano
Two Approaches to Lower the Chances of Recurrence of Anal Fistula After Surgery
A total of 80 patients with complex fistula in ano of both genders were included. All patients in Group A underwent a loose seton technique.
- Trial name
- NCT06380036
- Testing
- video assisted fistula tract surgery
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sairah Sadaf
Fistula in Ano, Crohn Disease
Pediatric MSC-AFP Sub-study for Crohn's Fistula
The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease.
- Trial name
- NCT03449069
- Testing
- MSC-AFP
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Fistula-In-Ano, Anal Fistula
Treatment of Anal Fistula With Lasercoagulation
The purpose of this study is to determine whether treatment with laser coagulation is an effective and safe treatment option for patients with anal fistula
- Trial name
- NCT03017898
- Testing
- Laser Coagulation
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Region Skane
Anal Fistula
3D Endoanal Ultrasound and Anal Fistula
The study aims to evaluate the use of 3D endoanal ultrasound in preoperative management of anal fistula disease.
- Trial name
- UFU (NCT03937752)
- Testing
- 3D endodanal ultrasound
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Anal Fistula
Treatment of Perianal Fistulas by Endorectal Advancement Flap Associated With Adipose Tissue Injection
The study aims to evaluate effectiveness of the association of endorectal advancement flap technique with local injection of autologous and micro-fragmented adipose tissue, obtained with the Lipogems® system, in patients with…
- Trial name
- Fistula_CM1 (NCT04750499)
- Testing
- Adipose tissue injection associated with endorectal advancement flap.
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Hospital Clinic of Barcelona
Anal Fistula
Multicenter Prospective Evaluation of Radiofrequency for Anal Fistulas
Anal fistula treatment is associated with increasing risk of anal incontinence until 40% of cases. New and alternative treatments (glue, advancement flap, plug…) decrease this risk, but with fistula efficacy treatment in 40 to…
- Trial name
- RADIOFIST (NCT03131297)
- Testing
- treatment by radiofrequency
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- F Care Systems NV