Clinical trials: Rectal Prolapse, open to volunteers
Hemorrhoid Bleeding, Hemorrhoids Prolapse
Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease
The goal of this observational study is to evaluate the effectiveness of topical nifedipine 0.3% plus lidocaine 1.5% for uncomplicated hemorrhoidal disease.
- Conditions
- Hemorrhoid Bleeding, Hemorrhoids Prolapse, Hemorrhoid Pain, Hemorrhoid
- Trial name
- NILOS (NCT07295886)
- Testing
- topical nifedipine 0.3% plus lidocaine 1.5%
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Cardarelli Hospital
Hemorrhoid, Hemorrhoid Prolapse
Data-driven Clustering in Hemorrhoid Surgery: Retrospective Monocentric Study for the Identification of Clinical Phenotypes
This retrospective, single-center observational study will use routinely collected perioperative data from adults undergoing surgery for symptomatic hemorrhoidal disease to identify data-driven clinical phenotypes.
- Trial name
- PROCTO-CLUSTER (NCT07427927)
- Testing
- Any surgical procedure for hemorrhoidal disease
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Pelvic Floor Prolapse, Functional Constipation
Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse
- Conditions
- Pelvic Floor Prolapse, Functional Constipation, Rectocele
- Trial name
- NCT04547816
- Testing
- Biofeedback therapy, Tibial neuromodulation, Pelvic floor muscles training
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Federal State Budgetary Scientific Institution
Colorectal Carcinoma, Rectal Prolapse
Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
Robotic assisted surgery has been performed for more than two decades with good success and safety profile. However, there was only one dominating robotic surgical system available in the past which led to high cost for robotic…
- Conditions
- Colorectal Carcinoma, Rectal Prolapse, Prostate Cancer (Adenocarcinoma), Bladder Cancer
- Trial name
- NCT06926374
- Testing
- Robotic surgery using the Sentire Surgical System
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Colorectal Disorders, Prolapse
Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery
This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.
- Conditions
- Colorectal Disorders, Prolapse, Prolapse Rectal, Prolapse Genital
- Trial name
- ProTex (NCT06430931)
- Testing
- Minimal invasive abdominal prolapse surgery using Polypropylene mesh, Minimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh
- Where
- Netherlands
- Volunteers
- 184 people
- Sponsor
- Meander Medical Center
Colo-rectal Cancer, Rectal Prolapse
Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery
Currently a multiport robotic surgery platform (Intuitive Xi) is widely available and used for colorectal surgery indications. A Single port platform (Intuitive SP) is FDA approved for Head and Neck and Urology but has not been…
- Conditions
- Colo-rectal Cancer, Rectal Prolapse, Colostomy Stoma, Colorectal Disorders
- Trial name
- NCT05321134
- Testing
- Single port robotic colorectal surgical procedure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Internal Hemorrhoid, Rectal Prolapse
CAES for Internal Hemorrhoids and Rectal Prolapse
Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy.
- Trial name
- NCT04169152
- Testing
- Cap-assisted endoscopic sclerotherapy
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Faming Zhang
Rectal Prolapse
FOAM: Functional Outcome After Ventral Mesh Rectopexy
Rectal prolapse is a protrusion of rectal wall through the anus. A surgical technique called Ventral mesh rectopexy has become a standard procedure for this condition in many centers.
- Trial name
- NCT06455501
- Testing
- Ventral mesh rectopexy
- Volunteers
- 70 people
- Sponsor
- Uppsala University
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Rectal Prolapse, Surgery
The Nordic Rectal Prolapse Study
The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: Which procedure is best for treating external rectal prolapse?…
- Conditions
- Rectal Prolapse, Surgery, Recurrence, Quality of Life
- Trial name
- NORDIC (NCT05569980)
- Where
- Denmark
- Volunteers
- 430 people
- Sponsor
- Aarhus University Hospital
Vaginal Vault Prolapse, Uterine Prolapse
Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment
This prospective cohort study investigates the surgical outcomes of laparoscopic pectopexy and laparoscopic colporraphy performed at the Wellbeing Services County of South Ostrobothnia.
- Conditions
- Vaginal Vault Prolapse, Uterine Prolapse, Cystocele, Midline, Rectocele; Female
- Trial name
- NCT06902909
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital