Clinical trials: Rectum Cancer
Liver Cancer, Pancreatic Cancer
Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos
The study consists in a co-clinical trial by using zebrafish embryos. Specifically, an observational prospective clinical trial on patients operated of epato-biliar-pancreatic cancers and gastro-intestinal cancers undergoing a…
- Conditions
- Liver Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer
- Trial name
- xenoZ (NCT03668418)
- Testing
- Fluorouracil, Lederfolin, Oxaliplatin
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Colon Cancer, Rectal Cancer
Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy
The investigators' null hypothesis is that a withdrawal time of 9 to 10 minutes is non-inferior to a withdrawal time of 12 minutes or greater.
- Conditions
- Colon Cancer, Rectal Cancer, Colorectal Cancer
- Trial name
- NCT05018325
- Testing
- Colonoscopy with 6 minute withdrawal, Colonoscopy 9 minute withdrawal, Colonoscopy 12 minute withdrawal
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cancer of Colon, Cancer of Rectum
Colorectal Health Research Champions
The purpose of the Colorectal Health Research Champions program is to provide accurate and reliable colorectal health cancer information that they can share within their communities to encourage cancer prevention, screening, and…
- Trial name
- NCT04812743
- Testing
- Colorectal Health Research Champions
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Neoadjuvant Chemoradiotherapy
Hyperpolarized 13C-MRI and Radiomics in Rectal Cancer
This study is testing new imaging and analysis methods to improve how doctors predict treatment response in rectal cancer patients receiving chemoradiotherapy.
- Trial name
- DNP_RECA (NCT07730541)
- Testing
- Hyperpolarized 13C-MRI (HP 13C-MRI)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy Subject
Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer
This trial studies how fiber and fish oil supplements affect the metabolism and activities of colon cells in healthy individuals.
- Trial name
- NCT04211766
- Testing
- Dietary Fiber, Fish Oil, Comparator
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Colo-rectal Cancer, Anesthesia
Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?
This study is a randomized, double blind controlled trial examining the impact of incorporating a single intraoperative intravenous magnesium bolus and infusion into a preexisting Enhanced Recovery After Surgery (ERAS) protocol…
- Trial name
- NCT05021263
- Testing
- IV Medications
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Rectal Cancer
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer
Preoperative chemoradiation leads to increased pelvic control and overall survival, but both distant and local disease control remain problematic in locally advanced rectal cancer patients.
- Trial name
- NCT00113230
- Testing
- Avastin (Bevacizumab, RHUMAB VEGF), Capecitabine, Radiation Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer
Oligogenic Determinism of Colorectal Cancer
The majority of the clinical situations suggestive of an increased genetic risk for colorectal cancer (CRC) are not explained by a simple monogenic model.
- Trial name
- DOCC (NCT01057953)
- Testing
- Blood drawn
- Where
- 16 sites in France
- Volunteers
- 1,550 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Rectal Neoplasms
Virtual Ileostomy Versus Conventional Loop Ileostomy
This study aimed at comparing the Comprehensive Complication Index (CCI), readmission rates, postoperative hospitalization days, duration of bearing the stoma (months), hospitalization costs, the number of hospitalizations with…
- Trial name
- NCT05985252
- Testing
- Virtual ileostomy, Diverting ileostomy
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Colorectal Cancer
Increasing Colorectal Cancer Screening in African Americans
RATIONALE: Screening may help doctors find colorectal cancer sooner, when it may be easier to treat. Finding out what affects a patient's decision to undergo screening tests may help increase the number of patients who undergo…
- Trial name
- NCT00893295
- Testing
- informational intervention, medical chart review, screening questionnaire administration
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Quality of Life, Sexual Function
Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial
Quality of life after rectal surgery is reported to be impaired. Side effects of surgery and/or neoadjuvant treatment as functional disturbances like sexual dysfunction, urinary incontinence, anal incontinence or stoma problems…
- Conditions
- Quality of Life, Sexual Function, Urinary Incontinence, Anal Incontinence
- Trial name
- NCT00895388
- Testing
- Structured Rehabilitation program
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Anastomotic Leak
Quantification of Anastomostic Blood Flow With Fluorescence Imaging in Low Anterior Resection for Rectal Cancer
A serious and life-threatening complication to rectal surgery is anastomotic leakage, AL. In Denmark, approximately 800 patients every year, are operated for rectal cancer, 50% of these with resection and anastomosis.
- Trial name
- FILAR (NCT05627934)
- Testing
- qICG
- Where
- Denmark
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Colorectal Cancer
Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants
RATIONALE: Developing a personalized screening plan may be more effective than usual care in increasing the number of healthy participants who regularly undergo screening for colorectal cancer.
- Trial name
- NCT00617071
- Testing
- medical chart review, survey administration, fecal occult blood test
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Healthy Volunteers, Rectal Cancer Patients
To Evaluate Dose and Safety of NanoEcho Particle-1 Using NanoEcho Imaging Device Examinations of Rectal Lymph Nodes in Healthy Volunteers and Rectal Cancer Patients.
Clinical nodal staging for rectal cancer tumours in early stages, is today shown to be unreliable and no precise or accurate methods exist.
- Trial name
- NCT06693375
- Testing
- Iron oxide nanoparticles, Rectal Magnetomotoric ultrasound (MMUS)
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NanoEcho AB
Colo-rectal Cancer
Development Study of Check-Cap Imaging System in Healthy Volunteers
To evaluate the performance of Check-Cap Imaging System in healthy volunteers in a variety of operating scenarios. The Back recorder unit is the primary module for evaluation The participants DO NOT ingest a capsule and the…
- Trial name
- NCT03989180
- Testing
- C-Scan System
- Where
- Israel
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic
Predictive Model For Anastomotic Leakage After Colorectal Cancer Surgery
This pilot study aimed to develop a simplified early postoperative model for AL risk stratification using readily available clinical and laboratory variables.
- Conditions
- Colorectal (Colon or Rectal) Cancer, Leak, Anastomotic, Surgery Complications
- Trial name
- Doesn't exist (NCT07709923)
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Rectal Cancer
A Questionnaire to Assess the Quality of Life of Rectal Cancer Patients With or Without Stoma
The aim of the present prospective study was to evaluate the prediction accuracy of EORTC QLQ-C30/C38 questionnaire in rectal cancer patient(RC).
- Trial name
- NCT01181557
- Where
- Italy
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Colon Cancer, Rectal Cancer
Clinical Study-evaluate Performance&Safety "Aer-O-Scope" in Colon of Low Risk Patients
A double center study to evaluate the safety and efficacy of the Aer-O-Scope in traveling through the colon in low risk subjects.
- Trial name
- NCT00867724
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colo-rectal Cancer
Clinical Application of an Automated Liquid Biopsy Platform for Early Detection of Colorectal Cancer
Colorectal cancer (CRC) is among the most preventable cancers when precancerous lesions are detected at an early stage. Current screening methods for CRC require bowel prep or stool-based testing that are inconvenient, resulting…
- Trial name
- NCT03476122
- Where
- Taiwan
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- CellMaxLife