Clinical trials: Recurrent
Low Back Pain, Respiratory Loading
Inspiratory Resistive Loading and Proprioceptive Postural Control
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Conditions
- Low Back Pain, Respiratory Loading, Proprioceptive Impairment
- Trial name
- NCT01541020
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Diarrhea
Zinc Supplementation and Severe and Recurrent Diarrhea
Evaluating the impact of 3 months daily zinc supplementation on incidence of severe and recurrent diarrhea in 6 to 36 months age children in Bandarabbaas
- Trial name
- NCT01306097
- Testing
- Zinc Supplement
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Clostridium Difficile Infection Recurrence
Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
The purpose of this study is to determine whether a single strain capsulated probiotic, when used after standard C. difficile antibiotic therapy, is effective in reducing the risk of infection recurrence mediated by a decrease in…
- Trial name
- NCT05606159
- Testing
- Bacillus velezensis DSM 33864
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novozymes A/S
Endometrial Cancer
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT01150682
- Testing
- RNA analysis, reverse transcriptase-polymerase chain reaction, enzyme-linked immunosorbent assay
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Gynecologic Oncology Group
Developmental Disorders
Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools
1. Inclusion of 5 families Inclusions will be made by the clinical genetics department of the Rouen University Hospital (monocentric study) and will correspond to trios of parents + child with unexplained developmental…
- Trial name
- RRMUT (NCT04564235)
- Testing
- genome-wide analyses, Search for de novo mutations in paternal sperm samples
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Depression - Major Depressive Disorder, Depression Bipolar
Digital Phenotypes for Predicting Depression
This longitudinal study aims to identify and validate digital phenotypes that can predict recurrence of major depressive episodes using passively collected, real-time sensing data from smartphones and wearable devices.
- Conditions
- Depression - Major Depressive Disorder, Depression Bipolar, Bipolar Disorder (BD), Mood Disorders
- Trial name
- NCT07151846
- Where
- South Korea
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Healthy Volunteers
Effects of THC and CBD on Human Episodic Memory Function
THC and CBD have distinct symptomatic and behavioral effects. In healthy individuals, THC can induce psychotic symptoms and anxiety, and can impair memory.
- Trial name
- NCT02291562
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Recurrent Genital Herpes Simplex Type 2
A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes
This study is designed to assess safety, tolerability, and pharmacokinetics (PK) of single ascending dose (SAD) of ABI-5366 in Part A in healthy participants and multiple-ascending doses (MAD) of ABI-5366 in Part B in…
- Trial name
- NCT06385327
- Testing
- ABI-5366
- Where
- 15 sites in Australia, New Zealand
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Assembly Biosciences
Gallstone
The Discovery of the Double Sphincter in Gallbladder
We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.
- Trial name
- NCT01998451
- Testing
- Tauroursodeoxycholic acid
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Steroid-Sensitive Nephrotic Syndrome
Rituximab in the First Episode of Paediatric Nephrotic Syndrome
The study will be a randomized, open-label trial in children with the initial episode of SSNS and whose state of complete remission after received standard prednisolone, to determine whether rituximab (a single intravenous…
- Trial name
- NCT05850546
- Testing
- Rituximab, Corticosteroid
- Where
- 3 sites in China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Recurrent Uti
Intravesical Gentamicin to Prevent Recurrent UTI
Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth…
- Trial name
- NCT06332781
- Testing
- Gentamicin, Nitrofurantoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Herpes Labialis
Iontophoretic Application of Acyclovir Cream to Treat Recurrent Herpes Labialis
Currently approved drugs for the treatment of herpes labialis (cold sores) exhibit low levels of efficacy due to the limited ability of the drugs to penetrate the skin to the site where the herpes virus is replicating.
- Trial name
- NCT00230867
- Testing
- iontophoretic acyclovir
- Where
- 26 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Transport Pharmaceuticals
Infertility
Intrauterine G-CSF Administration in RIF
Aim of this study is to investigate the effects of intrauterine G-CSF on endometrial thickness, clinical pregnancy rate and live birth rate in a recurrent implantation failure (RIF) group
- Trial name
- G-CSF (NCT03783208)
- Testing
- G-CSF, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Gurgan Clinic
Diaphragm Fatigue, Healthy
Inspiratory Resistive Loading and Diaphragm Fatigue
The aim of the study is to clarify whether specific loading of the inspiratory muscles induces contractile fatigue of the diaphragm muscle in healthy individuals and individuals with recurrent low back pain.
- Conditions
- Diaphragm Fatigue, Healthy, Low Back Pain
- Trial name
- NCT01505517
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Oral Ulcer
Clinical Efficiency of Natural Herbal Based Gel.
This clinical trial was conducted in School of Dentistry, Islamabad from 15th June 2023 to 16th January 2024. A total 202 participants took part in study and were divided equally into two groups i.e Control group and Experimental…
- Trial name
- NCT06490289
- Testing
- Denpro oral gel
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Crohn's Disease (CD)
Unraveling the Blood Microbiome in Postoperative Recurrence of Crohn's Disease
Crohn's disease, a chronic inflammation of the gastro-intestinal tract, is a disease with a complex pathogenetic background. Hereditary factors, environmental factors and the gut flora play a varying role in its onset, however…
- Trial name
- IBDbloom (NCT06770140)
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Recurrent Early Pregnancy Loss, Thyroid Diseases
Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienced recurrent pregnancy loss…
- Trial name
- NCT06036576
- Testing
- Levothyroxine Pill
- Where
- Iraq
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Colorectal Cancer (MSI-H), Molecular Residual Disease
Research on Colorectal Cancer Recurrence Monitoring and Individualized Treatment Based on MRD
This study aims to evaluate whether plasma molecular residual disease (MRD), assessed using circulating tumor DNA (ctDNA), can help optimize the duration of immunotherapy in patients with metastatic microsatellite…
- Trial name
- NCT07775950
- Testing
- Discontinue NA Treatment, Continued Immunotherapy, Observation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Acute Diverticulitis
Prospective and Multicentre Study on Clinical-biological Factors Predictive of Chronic Colon DIverticulitis
MAIN OBJECTIVE: Description of predicted markers of acute diverticulitis crisis, using bivariate and multivariate analyses. Analysis of acute diverticulitis predictor swings.
- Trial name
- DICRO (NCT04407793)
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sebastiano Biondo
Pilonidal Disease, Recurrence
Unroofing Curettage for Pilonidal Disease
This study aimed to investigate the outcomes of patients who underwent UC as the primary intervention for simple or complex SPD
- Conditions
- Pilonidal Disease, Recurrence, Healing Wound
- Trial name
- NCT05339828
- Testing
- unroofing curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital