Clinical trials: Recurrent Laryngeal Nerve Injury
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Thyroid Diseases, Recurrent Laryngeal Nerve Injury
Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery
Intraoperative neuromonitoring (IONM) of the recurrent laryngeal nerve during thyroidectomy is most commonly performed with surface electrodes embedded in the endotracheal tube (ETT).
- Conditions
- Thyroid Diseases, Recurrent Laryngeal Nerve Injury, Vocal Cord Paralysis, Thyroid Nodule
- Trial name
- TRANSCOMP (NCT07902349)
- Testing
- Transcartilage needle electrode recording, Endotracheal tube surface electrode recording
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Unilateral Vocal Cord Paralysis, Unilateral Vocal Cord Paresis
Recurrent Laryngeal Nerve Monitoring During Pediatric Aerodigestive Tract and Cardiac Surgery
This research studies whether a device used during surgery can help doctors better protect the nerve that moves a child's vocal cords. Damage to this nerve can affect speaking, swallowing, and sometimes breathing.
- Trial name
- NCT07604623
- Testing
- Intraoperative laryngeal nerve monitor
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Thyroid Disease, Recurrent Laryngeal Nerve Injury
Low-Current Stimulation for Recurrent Laryngeal Nerve Protection During Thyroid Surgery
This single-center prospective randomized interventional study evaluated whether intraoperative low-current stimulation could assist recurrent laryngeal nerve localization and reduce temporary recurrent laryngeal nerve injury…
- Trial name
- NCT07706699
- Testing
- 3 mA low-current stimulation-assisted recurrent laryngeal nerve identification, 5 mA low-current stimulation-assisted recurrent laryngeal nerve identification
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Vocal Cord Dysfunction, Vocal Cord Paralysis
Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation…
- Conditions
- Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy
- Trial name
- NCT06406725
- Testing
- Point-of-Care Ultrasound of the Airway
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Benign Multinodular Goiter, Thyroidectomy
Intraoperative Methylene Blue Spray for the Identification and Preservation of Vital Structures in Thyroidectomy
This randomized controlled trial aims to evaluate the efficacy of intraoperative methylene blue (MB) spray in improving the identification and preservation of the recurrent laryngeal nerve (RLN) and parathyroid glands (PGs)…
- Conditions
- Benign Multinodular Goiter, Thyroidectomy, Recurrent Laryngeal Nerve Injury, Hypoparathyroidism
- Trial name
- NCT07395388
- Testing
- Intraoperative topical methylene blue spray, Conventional Dissection
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Services Hospital, Lahore
Postoperative Vocal Cord Mobility, Recurrent Laryngeal Nerve Injury
C-MAC D-Blade vs Macintosh for Postoperative Vocal Cord Evaluation
This study compares two different laryngoscopes-the C-MAC D-Blade videolaryngoscope and the Macintosh direct laryngoscope-for evaluating vocal cord mobility after thyroidectomy.
- Trial name
- NCT07277985
- Testing
- Videolaryngoscope (C-MAC D-Blade), Direct Laryngoscope (Macintosh)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Esophageal Neoplasm, Anastomotic Leak
Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation
Analyze the correlation between the conformity of the anatomy (based on endoscopic examination) and postoperative anastomotic fistula and anastomotic stenosis; establish an anastomotic classification; and construct a predictive…
- Conditions
- Esophageal Neoplasm, Anastomotic Leak, Recurrent Laryngeal Nerve Injuries, Anastomotic Stenosis
- Trial name
- NCT06348381
- Testing
- No intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Chest Hospital
Thyroid Diseases, Surgery
NerveTrend vs. NerveAssure in Prevention of Recurrent Laryngeal Nerve Injury During Thyroid Surgery
The aim of this study is to compare two distinct modes of NIM Vital application in thyroid surgery: NerveTrend vs. NerveAssure mode with respect to prevalence of early postoperative RLN injury.
- Conditions
- Thyroid Diseases, Surgery, Recurrent Laryngeal Nerve Injuries
- Trial name
- NCT06289309
- Testing
- Neuromonitoring of the recurrent laryngeal nerves
- Where
- Poland
- Volunteers
- 264 people
- Sponsor
- Marcin Barczynski
Ligature; Hemorrhage, Recurrent Laryngeal Nerve Injuries
Comparison of Liagure Safety in Thyroidectomy With Conventional Thyroidectomy
To compare intraoperative and postoperative complication rates in thyroidectomy between ligasure and traditional vascular ligation and clipping .
- Conditions
- Ligature; Hemorrhage, Recurrent Laryngeal Nerve Injuries, Hypocalcemia
- Trial name
- NCT05684536
- Testing
- liagsure device
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imam Mohammad ibn Saud Islamic University
Methylene Blue, Recurrent Laryngeal Nerve Injuries
Methylene Blue Spray for Identification of Recurrent Laryngeal Nerve and Parathyroid Gland
Thyroidectomy is the procedure by which surgeons treat various thyroid diseases and is considered the commonest endocrinal surgery. Yet, it carries a risk for intraoperative complications.
- Conditions
- Methylene Blue, Recurrent Laryngeal Nerve Injuries, Parathyroid Gland
- Trial name
- NCT05113628
- Testing
- methylene blue identification
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Recurrent Laryngeal Nerve Injuries, Aortic Arch Hypoplasia
Recurrent Nerve Monitoring During Aortic Arch Repair
Almost half of newborns undergoing surgery to repair narrowing or interruption of the aortic arch will suffer injury to the recurrent laryngeal nerve.
- Trial name
- PREMAR (NCT04994964)
- Testing
- Electromyography
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Thyroid Diseases, Surgery
NerveTrend vs. i-IONM in Prevention of Recurrent Laryngeal Nerve Events During Bilateral Thyroid Surgery.
The aim of this study is to compare two distinct modes of NIM Vital application in thyroid surgery: i-IONM vs. NerveTrend mode with respect to prevalence of early postoperative RLN injury.
- Conditions
- Thyroid Diseases, Surgery, Recurrent Laryngeal Nerve Injuries
- Trial name
- NCT04794257
- Testing
- Neuromonitoring of the recurrent laryngeal nerves
- Where
- Poland
- Volunteers
- 264 people
- Sponsor
- Marcin Barczynski
Recurrent Laryngeal Nerve Injuries
CRANIO-CAUDAL AND LATERAL APPROACH FOR RECURRENT LARYNGEAL NERVE
The recurrent laryngeal nerve (RLN) dissection should be performed cranio-caudally in TOETVA approach.The aim of this study was to compare the cranio-caudal and lateral approach for RLN dissection in regard with the rates of LOS…
- Trial name
- NCT04379804
- Testing
- Lateral approach, Cranio-caudal approach
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Recurrent Laryngeal Nerve Injuries
Hydrodissection of Recurrent Laryngeal Nerve: Case Series
This study evaluates the hydrodissection technique in recurrent laryngeal nerve (RLN) dissection in thyroid surgeries. In this study hydrodissection of RLN was performed routinely in thyroid surgeries.
- Trial name
- NCT03907761
- Testing
- Hydrodissection
- Volunteers
- 34 people
- Sponsor
- Ankara University
Thyroid Cancer, Recurrent Laryngeal Nerve Injuries
Effect of Reversed Tracking Method for Identification of EBSLN in Thyroid Surgery
The feasibility and effectiveness of Reversed Tracking Method for the identification and protection of extralaryngeal nerve branches in thyroid surgery were analyzed.
- Trial name
- NCT03680222
- Testing
- Reversed Tracking Method
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Thyroid Cancer, Neck Cancer
Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring
In recent years, the application of intraoperative recurrent laryngeal nerve monitoring in thyroid surgery has greatly reduced the complications of recurrent laryngeal nerve injury.
- Conditions
- Thyroid Cancer, Neck Cancer, Recurrent Laryngeal Nerve Injuries, Accessory Nerve Injuries
- Trial name
- NCT03530033
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Bo Wang,MD
Recurrent Laryngeal Nerve Injuries
Recurrent Laryngeal Nerve's Motor Function: Sometimes Motor Fibers May Also Be Located in The Posterior Branch
The investigators hypothesized that, sometimes the posterior branch of the recurrent laryngeal nerve may also have motor function.
- Trial name
- NCT02493881
- Testing
- intraoperative neuromonitoring
- Volunteers
- 337 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital