Clinical trials: Reference Values
Contraception
Acceptability of Depo-subQ in Uniject
This is an observational study to assess the experience of current depot medroxyprogesterone acetate (DMPA) intramuscular (IM) clients and providers when they try Depo-subQ in Uniject and offer recommendations for the…
- Trial name
- NCT01667276
- Where
- 2 sites in Senegal, Uganda
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- FHI 360
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Healthy
Procalcitonin Test Reference Range Determination
Prospective, single-centre study in healthy volunteers to establish a reference range for the RAMP Procalcitonin (PCT) test. The primary objective of this study is to establish the reference range for measurement of PCT levels…
- Trial name
- PRO-H (NCT02591121)
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Response Biomedical Corp.
Coordination Disorder, Developmental
Normative Reference Values of Equilibrium Coordination Test Among Children
A cross-sectional study will be conducted recruiting children of age group 8-15 years. Pilot study has been conducted for the determination of the sample size.
- Trial name
- NCT05159297
- Testing
- Reference values
- Where
- India
- Volunteers
- 1,104 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Fat Soluble Vitamin Deficiencies and Disorders
Establishing Reference Ranges for Fat-Soluble Vitamins in Healthy Chinese Adults
Vitamins are essential micronutrients required for maintaining normal physiological functions and metabolism in humans. Among them, fat-soluble vitamins (FSV) such as vitamins A, D, E, and K are absorbed in the intestines in the…
- Trial name
- NCT06512688
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy Volunteer
LTA Assessement Using Aggregometer TA-8V (Stago®)
Exploring platelet functions requires aggregation tests platelet. The Haematology Laboratory of Hospices Civils de Lyon currently has two new TA-8V plate aggregation automatons® (Stago).
- Trial name
- NORMAGREG (NCT04269603)
- Testing
- Take blood (TA-8V (Stago®)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Neonatal Adaptation
Defining Reference Ranges for Cerebral Oxygenation In Neonates (COIN) During Immediate Neonatal Transition After Birth
Especially in neonates non-invasive methods are required for monitoring the complex changes during immediate transition after birth to improve assessment of neonate and eventually resuscitation.
- Trial name
- COIN (NCT04594824)
- Testing
- No Intervention
- Where
- Austria
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Aortic Aneurysm
Reference Values of Circulating Endothelial Progenitor Cells
Circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. However reference values have not yet been determined.
- Trial name
- ANOPEC2 (NCT01918969)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hopital Jean Minjoz
Hematological Diseases, Healthy Volunteers
Capillary and Venous Blood Count Parameters
The purpose of this study is to compare capillary blood count parameters with the corresponding venous samples to verify the hypothesis that capillary and venous blood count parameters are equivalent.
- Trial name
- NCT00390988
- Testing
- blood sampling
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Magdeburg
Contraception
Assessing Preference for 3 Female Condoms: A Comparative Evaluation of the PATH Woman's Condom, FC2 and the Reddy 6
Evaluation of preference for three female condoms (FC).
- Trial name
- NCT01452503
- Testing
- Path Women's Condom, FC2 female condom, Reddy 6 female condom (V-Amour)
- Where
- South Africa
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- FHI 360
Healthy Volunteer, Artery Disease
Normal Reference Values in Han Adults of Extremity Arterial Structure and Hemodynamics by High-frequency Ultrasound
In recent years, high-frequency ultrasound, due to its higher resolution, can clearly display the superficial vascular structure and blood flow, and can detect vascular lesions early, providing a new non-invasive tool for…
- Trial name
- NOVAEA-HFUS (NCT05970926)
- Testing
- high-frequency ultrasound
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
HIV Infections, HIV Seronegativity
A Phase I, Observer-Blind, Placebo-Controlled Study of the Chiron Vaccine HIV p24/MF59 Administered to Healthy HIV-Seronegative Adults
To evaluate the safety and tolerability of the Chiron vaccine human immunodeficiency virus (HIV) p24(25 or 50 micrograms)/MF59 in healthy HIV-1 seronegative adults.
- Trial name
- NCT00002204
- Testing
- HIV p24/MF59 Vaccine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chiron Corporation
Grip Strength, Hand Strength
Tyrannosaurus Flex: Finding the "Fair-ly Normal" Grip
The purpose of this study is to evaluate the performance of the Dinomometer and establish normative data to inform clinical standards and benchmarks for therapeutic practice.
- Trial name
- NCT07735195
- Testing
- Dinomometer
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
HIV Infections, HIV Seronegativity
A Study of Immune System Activity in Healthy Adults
The purpose of this study is to compare immune system activity in young people and older people who do not have HIV. This information will be compared to that of HIV patients in another study.
- Trial name
- NCT00014053
- Where
- 9 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lung Diseases
Paediatric and Adult African Spirometry II
Pulmonary function testing is the most widely used tool for the diagnosis, severity assessment, management, risk factor categorization and follow-up of individuals with chronic lung disease.
- Trial name
- PAASII (NCT03038698)
- Where
- South Africa
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Lymphedema, Secondary
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
- Trial name
- NCT04457375
- Testing
- TDC
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Prostate CA
Trans and Non-binary Prostate-Specific Antigen Reference Interval Determination Study
The prostate specific antigen (PSA) blood test can help diagnose prostate problems, including cancer. The prostate is an organ in the pelvis. It is found in cisgender men, transgender (trans) women and some non-binary people.
- Trial name
- TransPRIDE (NCT06987045)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Congenital Sucrase-Isomaltase Deficiency
Adult Pilot Study for Reference Ranges and Optimal Cut-offs for the Sucrose Challenge Test and Sucrose Breath Test
An adult pilot study to establish the normal reference range and optimal cutoffs for the oral 50g Sucrose Challenge Test (SCT) and the 50g 13C-Sucrose Breath Test (CBT) for patients with CSID and healthy controls.
- Trial name
- NCT05045495
- Testing
- Sucrose Hydrogen Methane Breath Test
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- QOL Medical, LLC
Healthy Adults, Pulmonary Hypertension
A Multicenter Study on the Normal Reference Range and Clinical Significance of the Right Atrioventricular Coupling Index Assessed by Artificial Intelligence-Based Three-Dimensional Echocardiography
This multicenter study aims to establish the normal reference range of the Right Atrioventricular Coupling Index (RACI) in healthy Chinese adults using AI-based 3DE technology.
- Conditions
- Healthy Adults, Pulmonary Hypertension, Tricuspid Regurgitation, Heart Failure
- Trial name
- NCT07292896
- Where
- 25 sites in China
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Echocardiography, Stress, Reference Values
Echocardiographic Assessment of the Right Ventricle in Healthy Subjects During Stress Test in the Mexican Population
The echocardiographic indices of the right ventricle function vary significantly with demographic and anthropometric of each population factors and are associated with poor prognosis in several cardiovascular diseases.
- Trial name
- ECORVStressMx (NCT04286854)
- Testing
- Stress echocardiography with semi-supine bicycle
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miguel Ayala León