Clinical trials: Reflex Sympathetic Dystrophy
Neuropathic Pain, Complex Regional Pain Syndrome Type 1
Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)
Complex Regional Pain Syndrome type 1 (CRPS1) is a disabling pain syndrome. Its definitive treatment has not been established and the results of current treatments are often unsatisfactory.
- Trial name
- MESO-SDRC (NCT04650074)
- Testing
- LIDOCAINE 20 mg, LIDOCAINE 20 mg + KETAMINE 20 mg, LIDOCAINE 20 mg + KETAMINE 40 mg
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Complex Regional Pain Syndrome
Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Complex Regional Pain Syndrome is a debilitating and extremely difficult to treat condition. There is a large body of evidence demonstrating the therapeutic value of N-methyl-D-aspartate (NMDA)-receptor antagonists in CRPS.
- Trial name
- NCT00579085
- Testing
- Ketamine, IV NSS, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University College of Medicine
Neuropathic Pain, Complex Regional Pain Syndrome
IV Lidocaine Infusion for Neuropathic Pain
The investigators will conduct a retrospective cohort study of patients who have undergone i.v. lidocaine infusions in the previous 2 years for suspected neuropathic pain of heterogeneous origin.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndrome, Chronic Pain
- Trial name
- NCT05731739
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Complex Regional Pain Syndrome (CRPS)
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Pain avoidance helps with survival. However, chronic pain patients often avoid valued life activities fearing onset or exacerbation of pain. Hence, pain avoidance no longer protects, but reduces quality of life.
- Trial name
- NCT07791966
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
CRPS Type II
Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II)
The purpose of this study is to investigated and evaluated the effectiveness of a new surgical technique for the treatment of severe chronic pain stages (Complex Regional Pain Syndrome Type II).
- Trial name
- NCT01392599
- Testing
- SUBCUTANEOUS VENOUS SYMPATHECTOMY (RSVS)
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Complex Regional Pain Syndrome
Comparative Effects of Mirror Therapy and Standard Physiotherapy in Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by persistent pain, sensory disturbances, motor dysfunction, and functional impairment, often following trauma or surgery.
- Trial name
- (CRPS) (NCT07332884)
- Testing
- Mirror Therapy, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- University of Lahore
Complex Regional Pain Syndromes
Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome
The primary purpose of this study is to determine the differences in response to treatment of complex regional pain syndrome with a closed-loop spinal cord stimulator if applied in the early phases (acute or subacute) versus the…
- Trial name
- NCT06421350
- Testing
- Spinal Cord Stimulation Device
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Scripps Health
Complex Regional Pain Syndromes
Peripheral Nerve Injections for CRPS
Background Complex regional pain syndrome (CRPS) is characterized by intense pain, loss of function, and associated with motor, trophic, sudomotor, and/or vasomotor changes of the affected extremity.
- Trial name
- NCT04744675
- Testing
- Triamcinolone Acetonide 40mg/mL, Saline Injection, Bupivacaine
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture
Prism Adaptation Therapy for CRPS Type 1
Complex Regional Pain Syndrome (CRPS) is a clinical condition characterized by pain that arises either without an identifiable triggering factor or with a severity disproportionate to the initiating event.
- Conditions
- Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture, CRPS (Complex Regional Pain Syndromes), Neuropathic Pain
- Trial name
- NCT07370012
- Testing
- The Prism Adaptation Therapy Group, The Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Etlik City Hospital
Complex Regional Pain Syndromes, Chronic Pain
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features.
- Trial name
- TORNADO (NCT04597866)
- Testing
- Multimodal rehabilitation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Complex Regional Pain Syndrome (CRPS)
Effectiveness of Transcranial Direct Current Stimulation (tDCS) in the Management of Complex Regional Pain Syndrome
Transcranial direct current stimulation (tDCS) is a non-invasive therapy increasingly used in facilities treating patients with chronic pain.
- Trial name
- ALGOSTIM (NCT07361692)
- Testing
- transcranial direct current stimulation
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Polyclinique de l'Europe
Complex Regional Pain Syndrome I (CRPS I)
CRPS-RISE Outcomes Registry
The goal of this observational study is to learn about how well neridronate keeps working in the months after treatment. For 12 or up to 24 months while the registry is open participants will answer online survey questions about…
- Trial name
- NCT07811362
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Ambros Therapeutics, Inc.
Complex Regional Pain Syndrome
Light Irradiation and Outcome for Neuropathic Pain
Background. Sympathetically maintained pain (SMP) can be effectively relieved by light irradiation to the area near stellate ganglion (SGI), which is applied as an alternative to sympathetic blockade.
- Trial name
- NCT03228160
- Testing
- Linearly Polarized Near-Infrared light Irradiation
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Complex Regional Pain Syndromes, Distal Radius Fractures
Prednisone for CRPS in Distal Radius Fracture
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system.
- Trial name
- NCT06453447
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Complex Regional Pain Syndrome, Type 1
A Study of the Effect of Lenalidamide on Complex Regional Pain Syndrome Type 1
The purpose of this study is to determine if lenalidomide is a safe and effective treatment for complex regional pain syndrome type 1 (CRPS).
- Trial name
- NCT00166452
- Testing
- Lenalidamide
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Complex Regional Pain Syndrome (CRPS)
Validity and Reliability of the Turkish Version of the Revised Bath CRPS Body Perception Disturbance Scale
This study aims to perform the cross-cultural adaptation of the Revised Bath Complex Regional Pain Syndrome Body Perception Disturbance Scale (r-B-CRPS-BPDS) into Turkish and to evaluate the validity and reliability of the…
- Trial name
- NCT07858812
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Democracy University
Pain
A Pilot Clinical Trial of Sympathetic Blockade With Botulinum Toxin Type A to Treat Complex Regional Pain Syndrome (CRPS): a Randomized, Double-Blind, Controlled, Crossover Trial.
Lumbar sympathetic blocks are part of the standard of care for treating patients with sympathetically-maintained pain (e.g. in complex regional pain syndrome or reflex sympathetic dystrophy- RSD).
- Trial name
- NCT00637533
- Testing
- Lumbar sympathetic block with Botulinum Toxin type A
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Complex Regional Pain Syndrome Type I of the Upper Limb
Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS)
The purpose of this study is to test a specific nerve stimulation protocol as therapeutic option in patients diagnosed with CRPS (complex regional pain syndrome) of the upper extremity.
- Trial name
- NCT01915329
- Testing
- RSS (repetitive sensory stimulation)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Complex Regional Pain Syndrome Type I
Effect of Kinesiotaping on Pain,Edema and Kinesiophobia in Patients With Complex Regional Pain Syndrome
Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support.
- Trial name
- NCT06302920
- Testing
- Kinesiotape
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Alanya Alaaddin Keykubat University