Clinical trials: Refractive Amblyopia
Amblyopia
Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Children
The objective is evaluation of GoCheck Kids, a smartphone application ('App'), for use as a photo screening device in a pediatric population to detect amblyopia risk factors (ARFs).
- Trial name
- NCT03447171
- Testing
- App Vision Screening
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Gobiquity Mobile Health
Myopia, Amblyopia
Real Word Study on Myopia Control With Repeated Red Light Therapy for Ages of 3~6 Years Old
Repeated Red Light Therapy had been used as an amblyopia therapy for children as well as the myopia control in primary schools. However, ultra low lever of red light therapy with irradiance of 0.37mW and 0.60mW effectiveness and…
- Trial name
- RMC (NCT05811598)
- Testing
- repeated ultra low lever red light
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Amblyopia, Anisometropia
Dichoptic Virtual Reality Therapy for Amblyopia in Adults
This was a randomized, masked, controlled study of the effect of a virtual reality, binocular, 3-dimensional video game on visual acuity and stereopsis in adult patients with amblyopia.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT02246556
- Testing
- Dichoptic therapy, Patching therapy, Dioptic (non-dichoptic) therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Francisco
Amblyopia, Strabismus
Attention-based Binocular Training for Impaired Stereopsis (BRAVE)
This study evaluates a novel attention-based binocular visual search training paradigm designed to improve stereopsis (stereo vision) in individuals with impaired binocular vision.
- Conditions
- Amblyopia, Strabismus, Anisometropia, Binocular Vision Abnormalities
- Trial name
- BRAVE (NCT07803458)
- Testing
- Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task
- Where
- 2 sites in Hong Kong
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
Amblyopia
Morning Versus Evening Patching in Childhood Amblyopia
To determine whether the time of day at which daily occlusion therapy is administered-morning, with 2 hours of patching completed within 07:00-10:00, versus evening, with 2 hours completed within 17:00-20:00-affects visual-acuity…
- Trial name
- NCT07294599
- Testing
- eye-patching
- Where
- 2 sites in Jordan
- Volunteers
- 84 people
- Sponsor
- Yarmouk University
Amblyopia
Comparison of Binocular Spectacle Prescription Versus Patching Therapy in Refractive Amblyopia Patients
This study will examine on Refractive Amblyopia patients, whose amblyopia started due to longstanding uncorrected refractive errors.
- Trial name
- NCT06739798
- Testing
- Exp Group, Control Group
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Superior University
Amblyopia
Light-deprivation Utilized to Mitigate Amblyopia
Amblyopia is an impairment in spatial vision caused by asymmetry in the quality of visual input across the two eyes during childhood.
- Trial name
- LUMA (NCT02685423)
- Testing
- Binocular deprivation 10 days, Vision training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Refractive Errors, Amblyopia
Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines
Pediatric eye patients receive infrared photoscreener screening and skiascopy as a part of routine examination to compare ability to detect amblyopia risk factors.
- Conditions
- Refractive Errors, Amblyopia, Strabismus, Development Delay
- Trial name
- 2WINbus (NCT03668067)
- Testing
- 2WIN photoscreener
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Alaska Blind Child Discovery
Strabismic Amblyopia, Refractive Amblyopia
Comparative Validation of "Blinq" and "2WIN" Vision Screeners
After 28 years of development, the binocular birefringence screener ("blinq," "Rebion") was commercially released. It need to be validated with AAPOS (American Association for Pediatric Ophthalmology and Strabismus) criteria in…
- Conditions
- Strabismic Amblyopia, Refractive Amblyopia, Strabismus
- Trial name
- NCT04195711
- Testing
- objective pediatric vision screen, "blinq,"
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alaska Blind Child Discovery
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Amblyopia
Evaluation of a Smartphone Application, GoCheckKids™ as a Photo Screening Tool in a Pediatric Population
Objective: Prospective evaluation of GoCheckKids™, a smartphone application ('App') as a photo screening device in a pediatric population to detect amblyopia risk factors (ARFs) Method: Photorefraction images are captured using…
- Trial name
- NCT03119675
- Testing
- GoCheck Kids (iOS), GoCheck Kids (Windows)
- Volunteers
- 358 people
- Sponsor
- Gobiquity Mobile Health
Amblyopia, Anisometropic Ambyopia
Visual Cortex Stimulation in Patients With Amblyopia
This study will examine whether direct current (DC) polarization (electrical stimulation) of the visual cortex can cause a temporary improvement of vision in an amblyopic eye of an adult.
- Conditions
- Amblyopia, Anisometropic Ambyopia, Amblyopia, Suppression
- Trial name
- NCT00097162
- Testing
- Anodal stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Anisometropic Amblyopia, Refractive Errors
Excimer Laser Surgery for Anisometropic Amblyopia
Study Objectives To compare the efficacy and safety of surgical treatment (PRK) versus non-surgical treatment of anisometropic amblyopia in children who have failed conventional treatment due to non-compliance or non-response.
- Trial name
- ATS19 (NCT03342235)
- Testing
- Photorefractive Keratectomy (PRK), Patching 2 hours per day, Excimer Laser System
- Sponsor
- Jaeb Center for Health Research
Anisometropic Amblyopia, Accommodation Disorder
Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)
Anisometropic amblyopia is when one eye has a much stronger glasses prescription than the other, causing poor vision in one eye, even with glasses, because the brain favours the better-seeing eye.
- Trial name
- ARIHA (NCT06286410)
- Testing
- Bespoke glasses prescription worn during amblyopia treatment.
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Hyperopia, Amblyopia
Effect of Peripheral Defocus on Axial Growth in Hyperopes
Hyperopia, also known as farsightedness, is a common type of refractive error where distant objects may be seen more clearly than objects that are near.
- Conditions
- Hyperopia, Amblyopia, Anisohyperopia
- Trial name
- NCT02686879
- Testing
- Multifocal contact lenses, Single vision contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aston University
Amblyopia, Anisometropia
Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska
"Adaptica" (Padova, Italy) designed a fixed-distance, dark portable tube with power and remote control for the "2WIN: photoscreener.
- Trial name
- NCT04068129
- Testing
- photoscreen
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Bilateral Refractive Amblyopia
Bilateral Refractive Amblyopia Treatment Study
The purpose of this study will be to: Determine the amount of visual acuity improvement with treatment of presumed bilateral refractive amblyopia Determine the time course of visual acuity improvement with treatment
- Trial name
- ATS7 (NCT00305955)
- Testing
- Spectacles
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia, Anisometropia
The Effect of Light Deprivation on Visual Functions in Adult Amblyopes
Amblyopia is a significant health problem, affecting up to 4% of the population in the United States. Amblyopia, commonly known as "lazy eye," is a developmental visual disorder in which one or both eyes suffer from poor vision…
- Conditions
- Amblyopia, Anisometropia, Visual Impairment
- Trial name
- NCT02799836
- Testing
- Blindfold
- Sponsor
- Boston Children's Hospital