Clinical trials: Refractive Ametropia
Refractive Ametropia
A Study to Evaluate the Clinical Performance and Safety of UNICON Silicone Hydrogel Daily Disposable Soft Contact Lenses
13 weeks, open-label, daily disposable contact lens dispensing study.
- Trial name
- NCT07322211
- Testing
- Treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 35 people
- Sponsor
- Unicon Optical Co. Ltd.
Eye Diseases, Ametropia
Comparison of Subjective Refraction Measurement With SiVIEW Software and by an Expert
Main objective Show that the equivalent sphere refraction measurements obtained by the SiVIEW software have no significant clinical difference with those obtained by an optometrist expert.
- Trial name
- NCT04185701
- Testing
- SiVIEW software, Expert
- Where
- France
- Volunteers
- 111 people
- Sponsor
- SiVIEW
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Presbyopia, Myopia
Intrastromal Correction of Ametropia by a Femtosecond Laser
This study evaluates the intrastromal correction of ametropia with a femtosecond laser made by 20/10 PERFECT VISION. This laser generates a beam of ultrashort, infrared pulses which enables very precise cuts in the cornea.
- Conditions
- Presbyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- ISCAF (NCT00928122)
- Testing
- Intrastromal Correction of Presbyopia, Intrastromal correction of Myopia, Intrastromal Correction of Hyperopia
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- 20/10 Perfect Vision
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Ametropia
Performance of Aspheric Hydrogel Lenses After a Refit With Sphere Silicone Hydrogel Lenses for 4 Weeks
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A aspheric lenses after a refit with fanfilcon A sphere lenses for 4 weeks of daily wear.
- Trial name
- NCT03835078
- Testing
- methafilcon A contact lenses, fanfilcon A contact lenses
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- CooperVision, Inc.
Refractive Ametropia
Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
The purpose of this clinical trial was to evaluate the clinical performance of a manufacturing process on a frequent replacement multifocal contact lens.
- Trial name
- NCT05765227
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Ametropia
Ocular Responses to Short and Long-term Lens Wear
The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with…
- Trial name
- NCT00722891
- Testing
- Purevision Lenses with ReNu Multiplus, Purevision Lenses with Optifree RepleniSH
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Safety and Efficacy of Different Add Powers With a New Presbyopic Lasik Treatment Algorithm
This is a prospective, comparative, randomized, controlled, open-label, single-surgeon, single-center PMCF clinical study whereby presbyopic patients undergoing refractive surgery will receive a SUPRACOR treatment for the…
- Trial name
- NCT04617080
- Testing
- SUPRACOR Regular, SUPRACOR Strong
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Contact Lens Wettability
The purpose of this study is to compare the wettability of contact lenses disinfected with three marketed contact lens care solutions.
- Trial name
- NCT00349063
- Testing
- soft contact lens, Soft contact lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Waterloo
Ametropia, Refractive Error
Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol
The goal of this clinical trial is to assess improvements in visual performance and patient outcomes in wearing new spectacle lenses in general population. The two spectacle lenses will be compared after two weeks of wearing.
- Trial name
- ATLANTIC (NCT07168564)
- Testing
- AVA lenses, Standard lenses
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Essilor International
Normal Subjects, Ametropia
Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes
The purpose of this study is to determine the average values of human ocular biometry and to correlate these values with visual function.
- Trial name
- Gullstrand (NCT01173614)
- Where
- Spain
- Volunteers
- 1,646 people, healthy volunteers welcome
- Sponsor
- European Vision Institute Clinical Research Network
Myopia, Ametropia
Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3
The purpose of this study is to evaluate the overall performance of PRECISION1™ contact lenses when compared to INFUSE™ contact lenses.
- Trial name
- NCT04942925
- Testing
- Verofilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Ametropia
Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens
The primary objective of thes study is to confirm that the ocular response to the Test lenses are similar to those of the Control lenses when used in a 1 week planned replacement, daily wear modality over a 1-month period.
- Trial name
- NCT01706770
- Testing
- enfilcon A, galyfilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia, Myopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses
The primary objective of this study is to evaluate the axis orientation of LID226397 toric contact lenses.
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT05959200
- Testing
- Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Ametropia
Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use
To evaluate the clinical performance of two monthly silicone hydrogel contact lenses in habitual wearers of frequent replacement (FRP) lenses when worn for 1-month.
- Trial name
- NCT05166902
- Testing
- Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
- Where
- 4 sites in United States, Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Ametropia, Hyperopia
Air Optix Night and Day Aqua (AONDA) Retrospective Study 1
The purpose of this study is to assess long term performance and safety of AONDA in a real world setting when worn as daily wear or continuous wear for vision correction.
- Conditions
- Refractive Ametropia, Hyperopia, Myopia
- Trial name
- NCT05790928
- Testing
- Lotrafilcon A spherical contact lenses
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- Alcon Research