Clinical trials: Refractive Assessment
Cataract, Lens Opacities
Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort
The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and…
- Conditions
- Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism
- Trial name
- BioBase (NCT05458661)
- Testing
- Clinical Prototype BioBase (SN 07 and SN 08)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Myopia, Hyperopia
Evaluation of Silicone Hydrogel Daily Wear Contact Lenses for Up to One (1) Month of Daily Wear
The aim of the study is to evaluate if the performance of Invigor A is substantially equivalent to Invigor B contact lenses when used in a one month recommended replacement, daily wear modality.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03722784
- Testing
- Invigor A (test), Invigor B (control)
- Where
- 6 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS \& Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
- Trial name
- NCT00347204
- Testing
- ketorolac (Acular LS), Nepafenac (Nevanac)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center For Excellence In Eye Care
Eye Cyclorotation Degree, Pupil Shift
Evaluation of Position-induced Cyclorotation Between Wavefront Measurement and Refractive Surgery by the Iris Registration Method
Cyclorotation of eyes may be affected by motion and orientation of the head and body. An automated alignment method with the technique of iris recognition was used to assess the amount and orientation of position-induced…
- Trial name
- NCT00943163
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia, Progressive
Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop
This is a Two-Stage Phase 1/2 study to evaluate the safety, tolerability and pharmacodynamics of CBT-009 eye drop in healthy volunteers.
- Trial name
- NCT05372991
- Testing
- CBT-009, Vehicle, Atropine Sulfate
- Where
- Australia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cloudbreak Therapeutics, LLC
Myopia
Visual Outcomes and Contrast Sensitivity After Myopic LASIK
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK procedure using the 200 kHz WaveLight® FS200 Femtosecond Laser and the WaveLight® Allegretto Wave® Eye-Q Laser.
- Trial name
- NCT01746589
- Testing
- bilateral myopic LASIK
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Daniel S. Durrie, MD
Astigmatism
Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism
Comparing Test Lens for Astigmatism Soft Contact Lens (Test) to 1-Day Control for Astigmatism contact lenses (Control).
- Trial name
- NCT03681808
- Testing
- Control, Test
- Where
- 13 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Corneal Astigmatism
Prospective Evaluation of Limbal Relaxing Incision (LRI) in Conjunction With Phacoemulsification Surgery for Astigmatic Correction in Chinese Eyes
The main purpose of this study is to evaluate the use of limbal relaxing incision (LRI) for astigmatic correction. LRI is a procedure where a pair of incisions is made in the peripheral part of the cornea so as to alter its shape…
- Trial name
- NCT01122992
- Testing
- Limbal relaxing incision
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Presbyopia
Investigation of the Presbia Flexivue Microlens™
The Presbia Flexivue Microlens is a corneal inlay.
- Trial name
- NCT02110472
- Testing
- Corneal inlay
- Where
- 11 sites in United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- PresbiBio, LLC
Refractive Error
Comparative Study of Two Marketed Spherical Soft Contact Lenses
The purpose of this study is to obtain objective and subjective clinical data to compare the performance of two soft contact lenses.
- Trial name
- NCT01582789
- Testing
- enfilcon A, senofilcon A
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Assessment of Bifocal and Prismatic Bifocal Spectacles for Myopia Control in Children
1. To determine if the effect of near-addition lenses (bifocals) is more prominent for children with high myopia progression. 2.
- Trial name
- NCT00787579
- Testing
- Bifocal spectacles, Prismatic bifocal spectacles
- Where
- Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Essilor International
Normal Cornea, Post Laser Refractive Surgery
Evaluation of RTVue in Corneal Measurement
The purpose of this study is to evaluate RTVue measurement of the cornea in various ocular conditions to include normal, pathology, post refractive surgery and cataract.
- Conditions
- Normal Cornea, Post Laser Refractive Surgery, Cornea Pathology, Cataract Surgery
- Trial name
- NCT01220193
- Where
- 2 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Optovue
Presbyopia
Assessment of Three Basic Progressive Lens Designs
This clinical trial investigates the differences between three different progressive addition lens designs. It is a non-invasive double-masked randomized clinical investigation. For this study, 80 participants will be recruited.
- Trial name
- NCT05252871
- Testing
- Progressive Additional Lenses (PAL), pre calibrated and made of polymeric material with anti-reflection coating
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Myopia
Evaluation of Visual Performance With Contact Lenses
This study will evaluate the influence of contact lens optical design on visual performance using standard and multifocal soft contact lenses (MFCLs).
- Trial name
- NCT03705130
- Testing
- Single Vision Contact Lens, Multifocal Contact Lens 1, Multifocal Contact Lens 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Houston
Myopia, Hyperopia
Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure
By using a new software two consecutive laser treatments have been combined to correct the distance vision and to provide a near vision component in addition to the first treatment.
- Conditions
- Myopia, Hyperopia, Presbyopia, Refractive Error
- Trial name
- Supracor (NCT01322919)
- Testing
- Supracor
- Where
- Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Myopia
Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses
The goal of this study is to compare the performance of two daily disposable silicone hydrogel contact lenses.
- Trial name
- NCT05805059
- Testing
- Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
- Where
- 4 sites in United States, Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Evaluation of Outcomes Using the Amo Advanced CustomVue Ilasik Procedure
The purpose of this study is to assess the efficacy, predictability and safety of the Advanced CustomVue™ iLASIK procedure (WaveScan WaveFront® System, STAR S4 IR™ Excimer Laser System and IntraLase™ FS System).
- Trial name
- iLASIK (NCT00765960)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Myopia
Myopia Control With Novel Eye Drops
Myopia currently affects 30% of the world and by 2050, almost 50% of the world will be myopic based on conservative estimates.1 In 2050, this will equate to almost 5 billion people with myopia, and those with high myopia will…
- Trial name
- NCT04301323
- Testing
- BHVI1 eye drops, BHVI2 eye drops, BHVI3 eye drops
- Where
- Vietnam
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Refractive Errors, Self-Examination
Comparison of a Smartphone Based Self Refraction Tool With Conventional Refraction Error Estimation Methods
Self evaluating tools based on smartphone devices are public available on the market for each person. The tools are used to estimate the existing refractive error for each eye of a patient. Hereafter, e.g.
- Trial name
- NCT03419351
- Testing
- Smartphone, Autorefractor, Individual
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Myopia
A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use
Evaluation of the clinical performance of a novel Bausch \& Lomb daily disposable contact lens when compared to the currently marketed Bausch \& Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and…
- Trial name
- NCT00784641
- Testing
- Novel Bausch & Lomb daily disposable contact lenses, Bausch & Lomb SofLens daily disposable contact lenses., Johnson and Johnson 1-Day Acuvue Moist contact lenses
- Where
- United States
- Volunteers
- 567 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated