Clinical trials: Refractive Error
Ametropia
A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices
The aim of this work is to investigate the clinical performance and subjective acceptance of the comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who have never worn contact lenses and who…
- Trial name
- NCT04067050
- Testing
- comfilcon A asphere, Spectacles
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors
Bifocal Lenses In Nearsighted Kids
This study will evaluate the use of two different bifocal contact lens add powers to prevent further nearsighted progression in children ages 7 to 11 years old.
- Trial name
- BLINK (NCT02255474)
- Testing
- Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Ohio State University
Refractive Error, Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a new CE marked daily disposable contact lens that contains a wetting agent to a recently improved daily disposable contact lens.
- Trial name
- NCT00634101
- Testing
- nelfilcon A, narafilcon A
- Where
- 20 sites in United Kingdom
- Volunteers
- 129 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses
This subject-masked, randomized, bilateral crossover study will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a…
- Trial name
- NCT04067141
- Testing
- somofilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Ametropia
Dispensing Study for the Phenacite Project
Dispensing Study for the Phenacite Project. The investigational test lens was not the final optical design and the study was not used for design validation.
- Trial name
- NCT02436005
- Testing
- Phenacite, comfilcon A
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Refractive Error
Comparative Study of Two Marketed Spherical Soft Contact Lenses
The purpose of this study is to obtain objective and subjective clinical data to compare the performance of two soft contact lenses.
- Trial name
- NCT01582789
- Testing
- enfilcon A, senofilcon A
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.
Ametropia
Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens
The primary objective of thes study is to confirm that the ocular response to the Test lenses are similar to those of the Control lenses when used in a 1 week planned replacement, daily wear modality over a 1-month period.
- Trial name
- NCT01706770
- Testing
- enfilcon A, galyfilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.
- Trial name
- NCT03888482
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 154 people
- Sponsor
- Alcon Research
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
- Trial name
- NCT03888469
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Ametropia
Performance of Aspheric Hydrogel Lenses After a Refit With Sphere Silicone Hydrogel Lenses for 4 Weeks
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A aspheric lenses after a refit with fanfilcon A sphere lenses for 4 weeks of daily wear.
- Trial name
- NCT03835078
- Testing
- methafilcon A contact lenses, fanfilcon A contact lenses
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- CooperVision, Inc.
Ametropia
Performance of Toric Hydrogel Lenses Following A Refit With Toric Silicone Hydrogel Lenses for 1 Month
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A toric lenses after a refit with fanfilcon A toric lenses for 1-month of daily wear.
- Trial name
- NCT03835221
- Testing
- methafilcon A toric contact lenses, fanfilcon A toric contact lenses
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Refractive Error
Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens
Subjects will wear 2 of 2 study contact lenses for a wearing time of approximately three to four hours at each of the visits in order to take measurements on binocular functional visual performance.
- Trial name
- NCT02886923
- Testing
- Hioxifilcon A Test, Hioxifilcon A With Cosmetic Ring Control
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
The Effects of Contact Lenses With Experimental Dye on Visual Function
This is a single-site, two-visit, contralateral, non-dispensing, randomized, controlled and subject-masked study to measure potential benefits of the new UV blocker.
- Trial name
- NCT03556579
- Testing
- senofilcon A with new UV blocker, senofilcon A
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Clinical Characterization of Symptomatic Populations
This is an unmasked, non-randomized, single arm, stratified, dispensing investigation of symptomatic and asymptomatic subject populations.
- Trial name
- NCT03319212
- Testing
- senofilcon A contact lenses
- Where
- 2 sites in United States, Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Refractive Error Correction
Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process
This study is a multi-site, group sequential, adaptive, randomized, double-masked, 2×2 crossover design, 1-week dispensing study.
- Trial name
- NCT03605303
- Testing
- Test/Control, Control/Test
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.