Clinical trials: Refractive Error - Myopia
Juvenile Myopia, Myopia
CYPRESS Efficacy and Safety Study Extension
This is an open-label, controlled, multisite, two-arm parallel group clinical trial of 36-month duration to evaluate the continued safety and efficacy of SightGlass Vision Diffusion Optics Technology (DOT) Spectacles in reducing…
- Trial name
- CYPRESS (NCT04947735)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 12 sites in United States, Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Diabetic Retinopathy, Myopia
OCTA Metrics Repeatability and Reproducibility in Different Disorders
Retinal imaging is a corner stone in diagnosis of most retinal disorders. Standard imaging techniques e.g. fluorescein angiography and color fundus photography have a lot of limitations including limited resolution, invasive…
- Conditions
- Diabetic Retinopathy, Myopia, Choroidal Neovascularization, Healthy
- Trial name
- NCT04488887
- Testing
- Optical coherence tomography angiography
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Myopia
Myopia Prevalence in Canadian School Children - a Pilot Study
The goal of this study is to determine the prevalence of nearsightedness in Canadian school children living in the Waterloo Region.
- Trial name
- Falcon (NCT01942057)
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics
This observational study aims to explore whether ultraviolet (UV) radiation and other environmental factors are associated with ocular biomechanical properties in healthy volunteers aged 18-44 years without ocular diseases…
- Trial name
- NCT06993077
- Testing
- environment Exposure
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use
Evaluation of the clinical performance of a novel Bausch \& Lomb daily disposable contact lens when compared to the currently marketed Bausch \& Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and…
- Trial name
- NCT00784641
- Testing
- Novel Bausch & Lomb daily disposable contact lenses, Bausch & Lomb SofLens daily disposable contact lenses., Johnson and Johnson 1-Day Acuvue Moist contact lenses
- Where
- United States
- Volunteers
- 567 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Evaluate the Safety and Efficacy of Two Types of Circular Column Modulated Lenses for Delaying the Progression of Myopia
Clinical trial to evaluate the safety and effectiveness of two kinds of ring band cylindrical lens in delaying the progression of myopia
- Trial name
- NCT05288335
- Testing
- Circular cylindrical mirror modulated frame glasses (compact), Circular cylindrical mirror modulated frame glasses (strong defocus), single vision frame glasses
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Clinical Evaluation on Using Personal Face Masks With Spectacles Versus Contact Lenses
The aim of this study was to explore satisfaction with vision correction and ease of use of PFM (Personal Face Masks) in a group of spectacle wearers who were randomised to continue wearing spectacles or be fitted with daily…
- Trial name
- NCT04658797
- Testing
- somofilcon A Daily Disposable Contact Lens, Single Vision Spectacle for Vision Correction, Personal Facemask
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia
To Study the Effects of Baby Drink on Vision Care
Baby Drink is a formula based on lutein, mixed with blueberry fermented liquid, vitamins and minerals. Lutein is an effective antioxidant to prevent retinal damage caused by blue light, but it cannot be produced in the human body…
- Trial name
- NCT05778201
- Testing
- Baby Drink group
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses
This study aims to compare the short-term clinical performance of the three contact lenses (Methafilcon A IV, Ocufilcon B 1-day and Omafilcon A 1-day daily disposable).
- Trial name
- NCT03235115
- Testing
- Methafilcon A IV, Ocufilcon B, Omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors
This study evaluates corneal epithelial thickness using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors.
- Conditions
- Myopia, Hyperopia, Astigmatism, Emmetropia
- Trial name
- NCT07647146
- Where
- Egypt
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Sohag University
Myopia, Astigmatism
Early Changes Among FLEx, LASIK and FS-LASIK
To evaluate the short-term changes in ocular surface measures and tear inflammatory mediators after lenticule extraction (FLEx), laser in situ keratomileusis (LASIK) and femtosecond laser-assisted laser in situ keratomileusis…
- Trial name
- NCT02551796
- Testing
- lenticule extraction, laser in situ keratomileusis, FS assisted laser in situ keratomileusis
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression (CSL)
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05724186
- Testing
- Test myopia control lenses (CSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Refractive Errors
Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention
The purpose of this clinical trial is to evaluate the effect of light-emitting diodes (LEDs) with a continuous spectrum of 430-780 nm for lighting in the classroom on myopia prevention among children in Grades 2 and 3.
- Conditions
- Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05728762
- Testing
- Novel LEDs
- Where
- China
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism
This single-site, randomized, double-masked (participant and investigator), 2-way crossover, repeated-measures dispensing study evaluated the visual performance of kalifilcon A daily disposable toric (LD213001) contact lenses…
- Trial name
- NCT05320042
- Testing
- kalifilcon A daily disposable toric contact lenses, Ultra for Astigmatism (samfilcon A) contact lenses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Study of Myopia Acquisition and Prevention
Purpose: To determine whether the use of reading glasses blocks the near work mediated increased incidence of myopia in healthy school children. Methods: SMART enrolled 115 emmetropic children (ages 7-9 years).
- Trial name
- SMART (NCT00477620)
- Testing
- Wearing of reading glasses during prolonged near work
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Freiburg