Clinical trials: Refractive Error - Myopia
Hyperopia, Myopia
Comprehensive Assessment of Multiple Products (CAMP)
The aim of this study is to assess contact lens performance and acceptance.
- Trial name
- NCT07276347
- Testing
- somofilcon A lens, stenfilcon A lens, fanfilcon A lens
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Comparison of LASIK and SBK
The objective of the study is to compare clinical outcomes from LASIK and SBK using FDA-approved laser technology on the same patient
- Trial name
- NCT00714363
- Testing
- LASIK, SBK
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Myopia, Environment
Environmental Factors and Myopia Prevalence Among Uyghur Students in Remote China
Ophthalmologic screening performs annually. Main information collected: gender, age, race, school, visual acuity, autorefractive results.
- Trial name
- NCT07119723
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
- Trial name
- NCT03888469
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Sphere Design Contact Lenses
The aim of this non-dispensing fitting study is to evaluate the short term lens fit, vision performance of three monthly replacement sphere lenses.
- Trial name
- NCT03098745
- Testing
- Omafilcon A, Somofilcon A, Omafilcon A - Proclear (PC)
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Refractive Errors
Real-World Study of Myopia Prevention and Control in Children
This prospective, school-based cohort study aims to enroll approximately 15,000 primary school students from multiple districts in Shanghai, China and to observe the outcomes on myopia prevention and control in children with…
- Conditions
- Myopia, Refractive Errors, Children, Cohort
- Trial name
- NCT06849895
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Keratomileusis, Laser In Situ
The Role of Psychosocial and Other Quality of Life Parameters in Evaluating Functional Changes Prior to and Following Laser In-situ Keratomileusis (LASIK)Changes Laser In-situ Keratomileusis (LASIK)
To evaluate the changes in quality of life parameters after LASIK surgery.
- Trial name
- NCT00344604
- Testing
- Role of psychosocial and quality of life parameters prior to and following LASIK.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Myopia, Astigmatism
A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System
The purpose of this study is to evaluate the safety and effectiveness of the ALLEGRETTO WAVE EYE-Q excimer laser system for the reduction of myopia with or without astigmatism in subjects undergoing photorefractive keratectomy…
- Trial name
- NCT01699087
- Testing
- Photorefractive keratectomy (PRK), ALLEGRETTO WAVE EYE-Q excimer laser system
- Volunteers
- 176 people
- Sponsor
- Alcon Research
Axial Myopia, Refractive Errors
Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure
The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye…
- Trial name
- NCT03552016
- Testing
- Oral Riboflavin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Myopia
Extension Study on Safety and Rebound Effect of SAT-001 for Myopia in Children
The objective of this clinical trial is to collect data on the rebound effect and long-term safety of SAT-001, a Software as a Medical Device (SaMD) under development for the inhibition and treatment of myopia progression in…
- Trial name
- NCT06742268
- Testing
- Single vision spectacles
- Where
- 5 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Myopic Choroidal Neovascularization
Ranibizumab for Myopic Neovascularization
The purpose of this study is to evaluate the clinical results of anti-VEGF intra-vitreal injections (IVT) in CNV secondary to pathologic myopia (PM-CNV).
- Trial name
- NCT01246089
- Testing
- ranibizumab injection
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Myopia, Severe
Large Cohort of 1000 Patients With Severe Myopia
The prevalence of myopia and severe myopia are increasing and will affect 50% and 10% of the population respectively. Severe myopia exposes an increased risk of glaucoma, cataract, retinal detachment and myopic maculopathy, a…
- Trial name
- MyoCo1000 (NCT05849974)
- Testing
- Structural and fonctional phynotyping
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Myopic Astigmatism
Rotational Stability of V4C Toric Implantable Contact Lenses After On Axis Implantation Measured With OPD Scan 3
The recently introduced toric V4c toric ICL (STAAR Surgical Company, Monrovia, CA, USA) has been designed with a 360-µm central hole to allow aqueous humor to flow without the need for an iridotomy.
- Trial name
- NCT03391544
- Testing
- V4c toric ICL implantation surgery
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Yonsei University
Myopia
Myopia Intervention in Children and Adolescents and Establishment of a Precise Intervention Model
Investigators are going to conduct a multi-centered randomized clinical trial that myopic children are randomly allocated into three groups: 0.01% atropine， 0.04% atropine and orthokeratology in order to evaluate the efficacy and…
- Trial name
- NCT05357326
- Testing
- Atropine Sulfate 0.01% Eye Drop, Orthokeratology, Atropine Sulfate 0.04% Eye Drop
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Validation of a Predictive Algorithm to Determine the Effectiveness of Orthokeratology for Myopia Control
This is a prospective study to validate a predictive algorithm for identifying fast progressing myopes.
- Trial name
- NCT04275635
- Testing
- Orthokeratology lenses
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Sun Yat-sen University
Myopia
The Effects of Low Dose Atropine on Choroidal Thickness
Atropine eye drops are considered to be an effective form of myopia control in human eyes. However, the mechanism by which it exerts it effects are not fully understood.
- Trial name
- NCT03544827
- Testing
- Atropine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia
Compelling evidence of genetic components in high myopia has been put forward by several studies. Twin cohorts, familial linkage studies and population studies has described at least 10 loci containing genes involved in the…
- Trial name
- ASSOMYP (NCT02583620)
- Testing
- blood sample
- Where
- 4 sites in France
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
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