Clinical trials: Refractive Errors
Myopia
Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers
This open-label study is of current Acuvue® Oasys® wearers (2 - week replacement, reusable lenses) who are satisfied with their current lenses.
- Trial name
- NCT06382064
- Testing
- Biweekly replacement contact lenses, One week replacement contact lenses
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Presbyopia
A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia
This is a 4-visit, multi-center, randomized, double-masked, parallel group study evaluating the safety and efficacy of CSF-1 in the treatment of presbyopia.
- Trial name
- NCT03885011
- Testing
- CSF-1, CSF-1 Component #1, CSF-1 Component #2
- Where
- 7 sites in United States
- Volunteers
- 166 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism
The aim of this study is to compare the clinical performance of the Biofinity Toric (comfilcon A) contact lens, versus Air Optix for Astigmatism (lotrafilcon B) over 1 month of daily wear.
- Trial name
- NCT01965288
- Testing
- comfilcon A, lotrafilcon B
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Myopia
Ophthalmic Compatibility During Seven Days of Continuous Wear of Silicone Hydrogel Lenses
The purpose of this study is to assess the ophthalmic compatibility of three different silicone hydrogel lenses worn on an overnight basis for six nights.
- Trial name
- QUINCE (NCT00934102)
- Testing
- Narafilcon A contact lens, Lotrafilcon A contact lens, Galyfilcon A contact lens
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- CIBA VISION
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3
It is a common clinical practice to leave small amounts of astigmatism uncorrected in contact lens wearers. Therefore, some drivers who have astigmatism and wear contact lenses may experience blur while driving.
- Trial name
- NCT02950545
- Testing
- Spherical Lenses, Toric Lenses
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Refractive Error
Clinical Evaluation of the Safety and Efficacy of FID 120947A
The purpose of this study is to evaluate the safety and efficacy of FID 120947A in soft contact lens wearers of Japanese ethnicity.
- Trial name
- NCT02771145
- Testing
- FID 120947A contact lens disinfecting solution, Soft contact lenses (SCL), SCL preservative solution
- Where
- Japan
- Volunteers
- 91 people
- Sponsor
- Alcon Research
Myopia
Daily Disposable Comparison Study
The objective of the study is to compare the overall subjective preference between two Daily Disposable hydrogel lenses when refitted into a third hydrogel lens.
- Trial name
- NCT02094677
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Comparing the Performance of 1 Day Multifocal Contact Lenses
The objective of the study was to compare the lens handling and performance of Lens A to habitually worn multifocal contact lenses and to the competitor Lens B.
- Trial name
- NCT04449263
- Testing
- Lens A, Lens B, Habitual Lenses
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
The purpose of this study is to assess improvement of palpebral roughness and associated symptoms with 3 months use of Clear Care®.
- Trial name
- NCT01996709
- Testing
- Hydrogen peroxide-based contact lens solution, Habitual contact lens solution, Habitual contact lenses
- Volunteers
- 142 people
- Sponsor
- Alcon Research
Presbyopia
A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT03017612
- Testing
- Raindrop Near Vision Inlay
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- ReVision Optics, Inc.
Refractive Errors
Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05431478
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Myopia
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
The objective of this orthokeratology study is to evaluate the safety and effectiveness of the Arise Orthokeratology Lens with non-spherical posterior peripheral curves
- Trial name
- NCT05984290
- Testing
- orthokeratology lens
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Refractive Error
WaveLight® Refractive Flap Accuracy Study
The purpose of this study is to evaluate the accuracy of the WaveLight FS200 femtosecond laser, as assessed by 1 day and 1 month post-operative optical coherence tomography (OCT) anterior segment corneal measurements compared to…
- Trial name
- NCT01941485
- Testing
- WaveLight® Refractive Suite, LASIK surgery
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Astigmatism
Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study is to compare the clinical performance of two different daily disposable, SiHy toric contact lens types, Lens A and Lens B, in existing soft lens wearers when worn for one week each.
- Trial name
- NCT04831515
- Testing
- Lens A, Lens B
- Where
- 4 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Initial Performance of a Modified Daily Disposable Contact Lens
The purpose of this study is to evaluate the incidence of ocular discomfort device-related adverse events with DAILIES TOTAL1® with UV Absorber (DT1 UV) contact lenses compared with current DAILIES TOTAL1® (DT1) contact lenses.
- Trial name
- NCT02694835
- Testing
- Delefilcon A contact lenses with UV Absorber, Delefilcon A contact lenses
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Astigmatism
Clinical Evaluation of Proclear Toric and Biofinity Toric
The aim of this study is to compare the short-term clinical performance of two Toric contact lenses.
- Trial name
- NCT06431061
- Testing
- Lens A (omafilcon B), Lens B (comfilcon A)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- CooperVision, Inc.