Clinical trials: Regeneration Muscle
Muscle Damage
Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration
The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration. The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
- Trial name
- NCT00832663
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Muscle; Injury, Quadriceps (Thigh), Tendon Strain
Mechanisms of Tissue Repair After Muscle Injury and Tendon Strain
The study is a 5-week human study including 24 18-35 year old healthy men. Each participant will have muscle injury and tendon strain induced in one leg using neuromuscular electrical stimulation in conjunction with forced…
- Trial name
- NCT05809947
- Testing
- Neuromuscular electrical stimulation
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Hypoxia
Effect of Hypoxic Exposure on Blood Variables in Elite Wrestlers
Twelve male wrestlers of the National Polish Team were observed in the study during the camp. The hypoxia group (n=6) participated in sports training and hypoxic exposure, while the control group (n=6) included wrestlers…
- Trial name
- NCT06373562
- Testing
- hypoxia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Duchenne Muscular Dystrophy
First in Human SAD/MAD Safety and PK Study With Adult DMD Safety and PK Cohort
This is a first-in-human (FIH), Phase 1 study of orally administered SAT-3247 in healthy adult volunteers (HVs) and adult participants with DMD to determine safety, tolerability, pharmacokinetics and pharmacodynamics.
- Trial name
- NCT06565208
- Testing
- SAT-3247
- Where
- 2 sites in Australia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Satellos Bioscience, Inc.
Muscle Injury
Nicotinamide (NAM) and Pyridoxine (vitamin B6) on Muscle Regeneration ("Satellite-01 Study").
Assessment of safety and efficacy of NAM/B6 oral administration on the amplification and commitment of satellite cells after a muscle injury
- Trial name
- NCT04874662
- Testing
- NAM/B6
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Exercise, Healthy Male/Female Subjects
Ketone Administration During Inactivity and Retraining
The aim of this study is to investigate the effect of oral ketone administration during inactivity-induced muscle atrophy and retraining-induced regeneration.
- Trial name
- NCT05398042
- Testing
- Ketone ester, Medium Chain Triglyceride (MCT) oil
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Protein Supplementation and Skeletal Muscle Healing Process
In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Intracellular Signaling in Skeletal Muscle
- Trial name
- NCT02816411
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Sarcopenia
Blood Flow, Muscle Regeneration and Sarcopenia
Due to the rapid aging of the population, sarcopenia is among the greatest challenges facing the health care system over the next quarter century.
- Trial name
- NCT01035060
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Florida
Inflammatory Responses, Muscle Fatigue
Effectiveness of Chocolate Milk in Recovery Among Highly Trained Kayakers: A Metabolic and Inflammatory Perspectives
Kayaking requires high energy expenditure and optimal metabolic adaptation for performance and recovery. While research on other sports exists, the effects of chocolate milk on kayakers' recovery remain unexplored.
- Conditions
- Inflammatory Responses, Muscle Fatigue, Recovery Time, Hunger
- Trial name
- Kayakers2025 (NCT06935058)
- Testing
- Chocolade milk
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Muscle Injury
Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans
Successful skeletal muscle regeneration depends on a functional pool of muscle stem cells, termed satellite cells (SC). SC are in a quiescent state throughout adulthood, but undergo multiple cycles of proliferation and…
- Trial name
- NCT03754842
- Testing
- Nicotinamide Riboside/Pterostilbene (500 mg/100 mg twice daily)
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Muscle Mass, Inflammation
New Protein Bar for Physically Active People
Post-exercise nutrition is an important factor in a nutrition plan for physically active subjects. Focusing on that, the Serbian group is developing protein bars enriched with sports supplements.
- Conditions
- Muscle Mass, Inflammation, Regeneration Muscle
- Trial name
- NCT04007731
- Testing
- DrRip - high protein, high fibre and creatine load, Voltage energy bar
- Where
- Slovenia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zala Jenko Praznikar