Clinical trials: Regional Anaesthesia
Pain, Postoperative; Anesthesia, Regional, Arthroplasty, Replacement, Hip
Analgesic Efficacy of Continuous SESP vs Continuous FICB After Hip Arthroplasty
The primary objective of this prospective, randomized, observer-blinded controlled trial is to compare the postoperative analgesic efficacy of continuous intermediate-approach sacral erector spinae plane (SESP) block versus…
- Trial name
- SESP-HIP (NCT07516795)
- Testing
- Continuous Sacral Erector Spinae Plane Block, Continuous Fascia Iliaca Compartment Block
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Bach Mai Hospital
Anxiety
Melatonin vs Pregabalin for Anxiolysis and Sedation
preoperative melatonin, pregabalin or both will be given to all patients preoperative
- Trial name
- NCT05221151
- Testing
- Melatonin, Pregabalin, Ondansetron 4 MG
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Nerve Block, Anesthesia, Local
Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block
The aim of the study is to investigate how the combination of ropivacaine (a slow onset, long duration local anesthetic) with lidocaine (a rapid onset, shorter duration local anesthetic) affects the onset and duration of a…
- Conditions
- Nerve Block, Anesthesia, Local, Forearm Fracture, Surgery
- Trial name
- NCT06381622
- Testing
- Ropivacaine 0.5% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.75% Injectable Solution
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Nordsjaellands Hospital
General Anesthesia, Spinal Anesthesia
General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty
This study aims to compare general anesthesia and spinal anesthesia with local anesthetic infiltration for buccal mucosal graft (BMG) in urethroplasty.
- Conditions
- General Anesthesia, Spinal Anesthesia, Local Anesthetic Infiltration, Buccal Mucosal Graft
- Trial name
- NCT07074730
- Testing
- Spinal anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Advanced Ovarian Cancer
The IPLA-OVCA Trial, Intra-Peritoneal Local Anaesthetics in Ovarian Cancer
Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour.
- Trial name
- IPLA-OVCA (NCT04065009)
- Testing
- Ropivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Deep Brain Stimulation Surgery, Electrophysiology
Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia
The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp…
- Conditions
- Deep Brain Stimulation Surgery, Electrophysiology, General Anesthesia, Consciousness, Loss of
- Trial name
- NCT06400901
- Testing
- No interventions
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Ruijin Hospital
Regional Anesthesia for Postnephrectomy Pain
Ultrasound- Guided Mid Point Transverse Process to Pleura Block
Radical nephrectomy is the surgical process for the resection of malignant tumors of the kidney necessitating a subcostal flank incision.Mild to severe pain is observed in the postoperative period Ineffective pain management…
- Trial name
- NCT05806229
- Testing
- Mid transverse process to pleura block (MTP)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Anesthesia
Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia
The purpose of the study will be to demonstrate whether Mohs micrographic surgery can be performed with a lower total dose of local anesthesia (and greater patient safety) when using 0.5% lidocaine with 1:200,000 epinephrine…
- Trial name
- NCT00594542
- Testing
- lidocaine
- Volunteers
- 149 people
- Sponsor
- University of Pennsylvania
Regional Anesthesia, Anxiety
Uncontrolled Disinformation About Regional Anesthesia and Pregnant Patients.
Nowadays, hundreds of information about regional anesthesia are accessed from any internet search engine when a question is written about the methods of anesthesia that can be applied during C/S.
- Conditions
- Regional Anesthesia, Anxiety, Social Media Addiction, Spinal Anesthesia
- Trial name
- NCT05416541
- Testing
- social media
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Underdosing of Local Anesthetics, Anesthetics, Local
Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade
Peripheral nerve blocks with use of USG allowed visualisation of the structures and nerves and made the block administrations safe, quick and comfortable.
- Conditions
- Underdosing of Local Anesthetics, Anesthetics, Local, Peripheral Nervous System Agents, Physiological Effects of Drugs
- Trial name
- NCT03838120
- Testing
- Procedure/Surgery: bupivakain % 0,5
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Anesthetics, Local
EMLA Cream in Hysteroscopy Practice
The aim of this study is to investigate the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA®) applied to the uterine cervix for reducing pain during diagnostic hysteroscopy, using a visual analogue scale (VAS) for…
- Trial name
- NCT02640183
- Testing
- EMLA
- Volunteers
- 184 people
- Sponsor
- Ain Shams Maternity Hospital
Other Peripheral Nerve Disease
Comparison of the Analgesic Effect of Different Local Anesthetics in Interscalene Nerve Block for Shoulder Surgery
Several reports have compared the duration of action of levobupivacaine and ropivacaine as local anesthetic. The most widely used method for sensory function evaluation is though means of a pinprick test.
- Trial name
- NCT02691442
- Testing
- Ropivacaine 0.75%, Levobupivacaine 0.5%, Levobupivacaine 0.5% + epinephrin 1/200000
- Volunteers
- 30 people
- Sponsor
- University Hospital, Antwerp
Anesthesia, Local
Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Approach) for Perioperative Analgesia in Patients Undergoing Flank Incision Surgeries.
Severe perioperative pain experienced after surgical procedures performed by flank incision is mainly related to incision of many muscles.
- Trial name
- NCT03744923
- Testing
- transmuscular QL block, Transversus Abdominus Plane block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Dexmedetomidine Analgesia, Knee Surgery
Intravenous Regional Analgesia of Dexmedetomidine
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism…
- Trial name
- Dexmedetomidin (NCT07131579)
- Testing
- Normal Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Parkinson's Disease
Sub-thalamic Nucleus Stimulation in Parkinson Disease
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. This procedure performed in two steps using electrophysiology.
- Trial name
- PARKEO (NCT01817088)
- Testing
- New targeting procedure without electrophysiology, Classical neurosurgical procedure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Dental Anesthesia
MRI and Local Anesthesia
The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.
- Trial name
- MRI and LA (NCT07602686)
- Testing
- ddMRI
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Minnesota
Regional Anesthesia Morbidity
Safety of Regional Anesthesia in Ukraine: the Survey
The common using of ultrasound navigation makes an opportunity to develop the regional anesthesia. Regional anesthesia reduces the length of stay in the hospital, reduces the intensity of perioperative pain and decrease opioid…
- Trial name
- NCT05478629
- Testing
- Survey
- Where
- Ukraine
- Volunteers
- 182 people
- Sponsor
- Bogomolets National Medical University
Knee Osteoarthritis, Arthritis Knee
How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.
The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty.
- Conditions
- Knee Osteoarthritis, Arthritis Knee, Knee Disease, Opioid Use
- Trial name
- TRUE KnORTH (NCT04648072)
- Testing
- Adductor Canal Block, Periarticular Injection
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Health Sciences North Research Institute