Clinical trials: Regional Block
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Regional Anesthesia, Pain, Postoperative
Analgesic Efficacy of Single-shot Erector Spinae Block for Thoracic Surgery
The erector spinae plane (ESP) block is a novel regional anesthetic technique for the treatment of thoracic, cervical, and abdominal pain.
- Trial name
- AnESTh (NCT03419117)
- Testing
- ESP block
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Cancer, Postoperative Pain
PECS Block in Partial Mastectomy for Postoperative Pain Control
The aim of this study is to evaluate patients who are undergoing partial mastectomy or removal of breast tissue and see if a pectoralis nerve block (PECS) can provide a meaningful improvement in postoperative pain control over…
- Conditions
- Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
- Trial name
- PECS (NCT04086394)
- Testing
- Pectoral Nerve Block, Surgery without Nerve Block
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Main Line Health
Propofol Injection Pain
Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain
The goal of this clinical trial was to evaluate methods to prevent pain on intravenous administration of propofol during induction of anesthesia.
- Trial name
- BBLP (NCT07285980)
- Testing
- propofol, Lidocaine - Propofol Mixture, Lidocaine - Bier Block
- Where
- Tunisia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Asma Ladib
Knee Arthritis, Anesthesia, Local
The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers
The aim of this study is to evaluate the Popliteal Plexus Block (PPB) effect on motor nerve branches of the sciatic and femoral nerve, when using different volumes of local anesthetics for PPB.
- Conditions
- Knee Arthritis, Anesthesia, Local, Post Surgical Pain
- Trial name
- NCT05464862
- Testing
- Popliteal Plexus Block with 10 ml, Popliteal Plexus Block with 20 ml, Popliteal Plexus Block with 30 ml
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charlotte Runge
Post Operative Pain
Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block
Prospective, patient-blinded study utilizing a novel Continuous Reassessment Method that concomitantly considers both block success and block side effects (lung dysfunction) for brachial plexus nerve blocks.
- Trial name
- NCT05868993
- Testing
- Dose of 0.5% Ropivacaine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Education
Online Regional Anesthesia Resources - Are They Effective?
Anatomical-based ultrasound imaging has been one of the most rapidly advancing innovations in the field of regional anesthesia in recent years.
- Trial name
- NCT05290974
- Testing
- Self exploring of available online material on supraclavicular brachial plexus block, Conventional in-person teaching on supraclavicular brachial plexus block
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain
A Novel Concept for Continuous Peripheral Nerve Block - Sciatic Nerve
To investigate the function of a novel catheter for continuous peripheral nerve blocks in the popliteal nerve: Two key issues are investigated 1) Successful primary placement and function of the catheter for continuous peripheral…
- Trial name
- NCT02456597
- Testing
- lidocainhydrochlorid, Isotonic Saline
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kai Henrik Wiborg Lange
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain, Cataract
Midazolam Additive to Local Anesthetic in Peribulbar Block
Regional eye blocks are usually preferred for ophthalmic procedures. Peribulbar block (PBB) is a safe alternative for patients undergoing cataract surgery.
- Conditions
- Postoperative Pain, Cataract, Local Anaesthetic Complication, Midazolam
- Trial name
- NCT03397069
- Testing
- Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Reflex Sympathetic Dystrophy
Near-infrared Spectroscopic Measurement in Complex Regional Pain Syndrome
Recent clinical investigations have suggested that the cause of abnormal pain in complex regional pain syndrome could be ischemia and inflammation, due to poor blood flow to deep tissues from microvascular pathology.
- Trial name
- NCT01586377
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Femur Fracture
Comparing Suprainguinal Fascia Iliaca Block With Erector Spinae Plane Block in Hip and Proximal Femur Surgery
Most hip fractures occur in the elderly population. Opioid-related respiratory depression is more common in the elderly population but can cause severe brain damage or death.
- Conditions
- Postoperative Pain, Femur Fracture, Regional Anesthesia
- Trial name
- NCT05642975
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Marmara University
Nerve Block, Anesthesia, Local
Sensory Distribution of Lateral Femoral Cutaneous Nerve Block
The purpose of this study is to investigate and describe the anatomical distribution of the sensory outcome following LFCN block (LFCN = lateral femoral cutaneous nerve) in relation to the incisional lines after Total Hip…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT02957903
- Testing
- Ropivacaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Anesthesia, Local
Risk Factors of Inferior Alveolar Nerve Block Failure: a Dental Student-centered Study
Inferior alveolar nerve block anesthesia is one of the most commonly used regional block anesthesia in dentistry. The factors that determine the success of this type of anesthesia which is applied so frequently, are not reported…
- Trial name
- NCT05681546
- Where
- Turkey (Türkiye)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Infraclavicular Brachial Plexus Block
Pulse Wave Transit Time After Infraclavicular Block
This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block.
- Trial name
- NCT07669688
- Testing
- Ultrasound-guided infraclavicular brachial plexus block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Total Knee Replacement
Regional Anesthesia for Knee Prothesis Surgery
Comparison of the analgesics blocks (femoral, adductor canal and sciatic subgluteal nerve) for total replacement knee surgery.
- Trial name
- NCT02451605
- Testing
- Analgesic nerve blockade (Ropivacaine), Total knee replacement surgery.
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Liege
Symptomatic Irreversible Pulpitis
Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
The purpose of this study is to evaluate the success of inferior alveolar nerve block, after the local application of Mepivacaine plus Tramadol in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT02110966
- Testing
- Mepivacaine, Mepivacaine plus Tramadol
- Where
- Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine