Clinical trials: Regional Block
Regional Anesthesia Morbidity
M-TAPA vs Intraperitoneal Bupivacain vs Intraperitoneal Bupivacain +Dexmedetomidin
Laparoscopic cholecystectomy is a common abdominal surgery in Western countries, favored for its minimal invasiveness, leading to less pain, smaller scars, and quicker recovery.
- Trial name
- NCT06482229
- Testing
- application for postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Sivas State Hospital
Mechanical Dyssynchrony, Heart Failure
Evaluating Effects of a Left Bundle Branch Block
A left bundle branch block (LBBB) is related to abnormal cardiac conduction and mechanical asynchrony and is associated with hypertension and coronary artery disease.
- Conditions
- Mechanical Dyssynchrony, Heart Failure, Bundle-Branch Block
- Trial name
- NCT00269659
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Anesthesia
Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction.
In this study 60 adult patients will participate and divided into two groups (30 for each). The first group will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, while the…
- Trial name
- NCT07048834
- Testing
- lidocaine local anesthetic drug, articaine local anesthetic drug
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amjed Fouad Hussein
Anesthesia
Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study
The Transversus Abdominis Plane (TAP) block is the current standard of care for patients undergoing laparoscopic abdominal surgeries with the Enhanced Recovery After Surgery (ERAS) Protocol.
- Trial name
- NCT03490357
- Testing
- Control - Transversus Abdominus Plane Block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Local Anesthesia
Effect of Lidocaine With Magnesium Sulfate on the Success of the Inferior Alveolar Nerve Block
68 healthy patients pulpitis and requiring root canal therapy are selected. . Sampling was done in a simple and non-experimental way from a dental clinic in Isfahan, and then the samples were randomly assigned to one of the two…
- Trial name
- NCT03262857
- Testing
- use of magnesium sulfate with lidocaine in inferior alveolar nerve block
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Postoperative Pain, Anesthesia, Conduction
PANDA-Regional Feasibility Study of a Smartphone Pain Management Application
Despite the numerous benefits of peripheral nerve blocks (PNBs) over general anesthesia (GA) in a variety of surgical procedures, PNBs can be associated with increased post-operative pain if pain medications are not taken…
- Trial name
- NCT03369392
- Testing
- Panda application
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Cancer, Postoperative Pain
PECS Block in Partial Mastectomy for Postoperative Pain Control
The aim of this study is to evaluate patients who are undergoing partial mastectomy or removal of breast tissue and see if a pectoralis nerve block (PECS) can provide a meaningful improvement in postoperative pain control over…
- Conditions
- Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
- Trial name
- PECS (NCT04086394)
- Testing
- Pectoral Nerve Block, Surgery without Nerve Block
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Main Line Health
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Diaphragmatic Paralysis, Brachial Plexus Block
Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block
Arthroscopic shoulder surgery involves dynamic and severe postoperative pain. Interscalene brachial plexus block (IBPB) provides adequate analgesia but the spread of local anaesthetics administered causes a phrenic nerve block…
- Trial name
- REDOLEV-2019 (NCT04385966)
- Testing
- Interscalene brachial plexus block, Levobupivacaine Hydrochloride 2.5 MG/ML
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Regional Anesthesia, Postoperative Pain, Acute
Caudal Block and Transversus Abdominis Plane Block in Pediatric Inguinal Hernia Repair
Pediatric inguinal hernia repair (IHR) candidates experiences ordinarily mild to moderate pain, rarely severe pain in the postoperative period.
- Trial name
- NCT05286190
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Regional Anesthesia
Duration of Analgesia in Bier Block for Patients Undergoing Hand Surgery
Intravenous regional anesthesia (Bier block) is widely used as an anesthetic technique for operations of short duration of the distal upper or lower extremities Today, IVRA is still popular in many countries being used in the…
- Trial name
- NCT05578885
- Testing
- Bier block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Michael Bishay Shehata Keroles
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Surgery
Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce…
- Conditions
- Postoperative Pain, Surgery, Anesthesia, Local
- Trial name
- NCT03878888
- Testing
- Exparel 266 MG Per 20 ML Injection
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Regional Anesthesia Morbidity, Supratentorial Brain Tumor
Ketamine Versus Dexmedetomidine as an Adjuvant in Scalp Block in Supratentorial Brain Tumor Excision Surgeries
Supratentorial brain tumor surgeries are associated with significant nociceptive stimulation and postoperative pain, which may adversely affect patient outcomes.
- Conditions
- Regional Anesthesia Morbidity, Supratentorial Brain Tumor, Acute Pain
- Trial name
- NCT07698665
- Testing
- Scalp Block with Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Local Anesthetic Complication
Buccal Infiltration Technique Compared to Inferior Alveolar Technique
This study was conducted to compare the efficacy of the buccal infiltration technique with inferior alveolar nerve block technique for alleviation of intraoperative pain during pulpal treatment of second mandibular primary molars…
- Trial name
- NCT04812639
- Testing
- Buccal infiltration technique, Inferior alveolar nerve block technique
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pain, Postoperative, Anesthesia, Local
Comparison of Ultrasound-guided Brachial Plexus Blocks and Selective Distal Blocks in Terms of Anesthesia
Ultrasound-guided brachial plexus blocks (infraclavicular, axillary) can be applied as the main anesthetic method in hand and wrist surgeries, as well as single or combination block applications of the median, radial and ulnar…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Patient Satisfaction
- Trial name
- NCT05656625
- Testing
- descriptive
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Samsun University
IUD Insertion Complication, Pain Control
Study of Local Anesthesia as a Method to Decrease IUD Insertion Related Pain
Despite the high efficacy of intrauterine devices (IUDs), some women choose not to receive IUDs secondary to the pain associated with insertion.
- Trial name
- NCT01967017
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anesthesia, Local
Optimal Volume of Bupivacaine in Adductor Canal Nerve Block
To establish adequate volume of levobupivacaine 0.25% in adductor canal nerve block in unilateral cruciate ligament of the knee reconstruction surgery.
- Trial name
- NCT02557386
- Testing
- Levobupivacaine 5 mL, Levobupivacaine 10 mL, Levobupivacaine 15 mL
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile