Clinical trials: Regression
Cardiovascular Disease
Evaluation of Oral Alpha-Cyclodextrin for Decreasing Serum Cholesterol
Background: Cardiovascular disease (CVD) is a leading cause of death in developed countries. Although statin-type drugs are currently the most effective therapeutic agents for reducing CVD risk.
- Trial name
- NCT01131299
- Testing
- Alpha cyclodextrin
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stress, Complete Psychological Check Up
Cognition and Health in Adolescents, Mindfulness as Prevention of Stress.
The purpose of this study is to determine whether mindfulness is useful as primary prevention for psychological health in highschool students, primarily related to stress, and whether mindfulness can improve cognitive function.
- Conditions
- Stress, Complete Psychological Check Up, Sleep, Cognition - Other
- Trial name
- CHAMPS (NCT01457222)
- Testing
- Mindfulness intervention, Music relaxation
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Region Skane
Atherosclerosis
Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.
- Trial name
- NCT00926055
- Testing
- Ezetrol (Ezetimibe), Vytorin (Ezetimibe + Simvastatin)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University
Cesarean Section Pain
Postoperative in Cesarean Section, the Women Suffering from Pain Due to Wound "incisional Pain", High Level Laser One of Most Effective Methods That Promoting Healing and Decrease Pain so It Will Effective If Use in Decreasing Pain of Cesarian Section
High power laser is safe and effective methods, it's uses increasing one day after day in decreasing pain and promoting healing so its use in postoperative cesarian section will help mothers to overcome pain and return to ADLs…
- Trial name
- NCT06793293
- Testing
- High level laser, Non-steroidal anti- inflammatory drugs and antibiotics
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Food Selectivity
Effectiveness of the Just Right Challenge Food Club for Decreasing Food Selectivity and Increasing Mealtime Quality
This single subject study tested the effectiveness of the Just Right Challenge Food Club for decreasing food selectivity and increasing mealtime qualify for children with developmental disabilities.
- Trial name
- NCT03756844
- Testing
- Just Right Challenge Food Club
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Western Michigan University
Aggression
Are Character Building Lessons Effective in Decreasing Bullying Behaviors?
Through the use of an educational intervention, the object of this study is to reduce the prevalence of bullying behaviors among fifth grade school age children.
- Trial name
- NCT00431470
- Testing
- Six classroom based character building education lessons
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Dry Eye Syndromes
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear vs. Systane for Dry Eye Signs, Symptoms & Refractive Regression Associated With Myopic Laser in Situ Keratomilieusis (LASIK).
This study will evaluate and compare 2 artificial tears in their ability to reduce post LASIK dry eye signs and symptoms. The secondary endpoint of this study is to evaluate refractive regression in these patients.
- Trial name
- NCT00620893
- Testing
- PEG- 400 based artificial tear, Systane
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
CVD Risk, Physical Activity
The Effect of Physical Activity on Decreasing Risk Level
Objective: The aim of the first part of this study with two stages is to determine prevalence of CVD risk and the associated variables in individuals aged 40-65 years registered in a Family Health Center (FHC) in city center of…
- Conditions
- CVD Risk, Physical Activity, Nurse's Role, Risk Reduction
- Trial name
- NCT03501017
- Testing
- physical activity program, Routine Practice
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Healthy
Decreasing Rates of Illness in Kids (DRINK)
The purpose of this study is to determine the effectiveness of a cultured dairy drink with high concentrations of active L casei to reduce the cumulative rate of illness in daycare/school children ages 3 to 6.
- Trial name
- NCT00356382
- Testing
- Lactobacillus (L.) casei
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Sarcopenia, Back Pain
The "Free From Pain Exercise Book" Versus "The Back Book".
This pragmatic randomised control feasibility trial aims to investigate the effectiveness of the "Free From Pain Exercise Book" in comparison to "The Back Book" for reducing back pain in adults aged 60 and over.
- Conditions
- Sarcopenia, Back Pain, Arthritis
- Trial name
- NCT05359107
- Testing
- "The Free From Pain Exercise Book", "The Back Book"
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Talita Cumi Ltd.
Extensor Tendon Reconstruction
Effect of Shortwave Diathermy Versus Ultrasound Waves on Increasing ROM and Decreasing Pain After Extensor Tendon Reconstruction
tendon injuries can result in long-term sequelae, including chronic pain and mobility restrictions, and may warrant surgery. Ultrasound is sound with a frequency above 20,000 Hertz (Hz) and is undetectable by the human ear.
- Trial name
- NCT06113250
- Testing
- shortwave diathermy, ultrasound waves, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Smoking Cessation
The Effectiveness of Using E-Cigarettes for Smoking Cessation and Decreasing Risk of Diseases Among Heavy Smokers
The goal of this clinical trial is to evaluate effectiveness of using e-cigarettes as harm reduction strategy for smoking cessation and decreasing risk of diseases in heavy smokers.
- Trial name
- NCT05639790
- Testing
- Electronic cigarettes + Health Counselling, Health Counselling
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen Smoore Technology Limited
Primary Open Angle Glaucoma, Hypertension Ocular
Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion.
Glaucoma is among the leading causes for blindness in the western world. Elevated intraocular pressure (IOP) has been identified as the most important risk factor.
- Trial name
- GME (NCT02300818)
- Testing
- Pulsed Electromagnetic Field Therapy, Seawater eyedrops
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American Society Of Thermalism And Climatology Inc
Alcohol Abuse, Alcohol Drinking
Decreasing Alcohol Use Through Student Peer Leaders
Problematic alcohol use can lead to worse social and health related consequences for underserved minorities, requiring urgent intervention.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcohol Use Disorder, Alcohol Problem
- Trial name
- NCT04579068
- Testing
- Screening and Brief Intervention of Problematic Alcohol Use
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Carotid Atherosclerosis
Atherosclerosis Monitoring and Atherogenicity Reduction Study
This study was designed to estimate the effect of two-year treatment with time-released garlic-based drug Allicor on the progression of carotid atherosclerosis in double-blinded placebo-controlled randomized clinical trial.
- Trial name
- NCT01734707
- Testing
- Allicor
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute for Atherosclerosis Research, Russia
Aortic Regurgitation
Diastolic Dysfunction in Aortic Regurgitation
Follow-up study in patients with severe aortic regurgitation after successful valve replacement. Systolic and diastolic function were assessed and persistent diastolic dysfunction was observed late (7-10 years) after operation.
- Trial name
- NCT00976625
- Testing
- Aortic Valve Replacement
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bern
No Evidence of Disease
Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers
This clinical trial studies celecoxib in decreasing the damaging effects of sunburn in healthy volunteers. Celecoxib may reduce skin damage by blocking enzymes associated with sunburn in healthy volunteers.
- Trial name
- NCT02090933
- Testing
- Celecoxib, Laboratory Biomarker Analysis, UV Light Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Physical Inactivity, Sedentary Behavior
Children- Sit Less, Move More (C-SLAMM): Increasing Physical Activity and Decreasing Sedentary Behaviour in Children
The Children Sit Less, Move More (C-SLAMM) study aims to test the feasibility and potential effect of a multi-component school and home-based pilot cluster randomized control trial on reducing sedentary behavior and increasing…
- Conditions
- Physical Inactivity, Sedentary Behavior, Health Behavior, Child Behavior
- Trial name
- NCT05854355
- Testing
- C-SLAMM Study
- Where
- United Kingdom
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Ulster
White Spot Lesion
Evaluation of Remin Pro Forte Versus Remin Pro on Treatment of White Spot Lesions Post Orthodontic Treatment
randomized clinical trial to evaluate caries regression, the change in colour and mineral content of the demineralized enamel after treatment with Remin Pro Forte paste (fluoride, hydroxyapatite, xylitol, ginger, and curcuma) and…
- Trial name
- NCT04017884
- Testing
- Remin Pro Forte, Remin Pro
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stereolithography, Dental Implants
The Use of Bone-, Tooth- and Mucosa- Supported Stereolithographic Guides for Dental Implant Placement
Introduction: The use stereolithographic (SLA) guides may provide significant benefits in simultaneous placement of multiple implants, especially in large edentulous areas lacking anatomic landmarks for surgical reference.
- Conditions
- Stereolithography, Dental Implants, Prosthesis
- Trial name
- stereolitho (NCT01027442)
- Testing
- Mucosa-supported single-type guides, Bone-supported guides, Dental Implants
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Istanbul University