Clinical trials: Regression
Human Healthy Volunteers
Normative Values and Forming Regression Equations for One Minute Sit to Stand Test in Healthy Normal Indian Population
This study is to find relation between number of repetitions the volunteer able to sit and stand in an armless chair and their age, height, weight and gender.
- Trial name
- 1minSTS (NCT02218905)
- Testing
- Sit to stand test
- Where
- India
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Baskaran Chandrasekaran
Patient Satisfaction, Cesarean Section
Decreasing Patient Dissatisfaction With Unplanned Cesarean Sections
Patient satisfaction after an unplanned cesarean section was studied and in the previous study it was noted that there were common themes that lead to patient dissatisfaction.
- Trial name
- NCT02472327
- Testing
- Pre-operative support
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Albany Medical College
Postoperative Pain
Decreasing Postoperative Pain Following Endometrial Ablation
To determine whether paracervical injection of long acting local anesthesia decreases postoperative pain following endometrial ablation under general anesthesia.
- Trial name
- NCT02660918
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Urinary Tract Infections, Spinal Cord Injuries
Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury
A non-randomized study evaluating the efficacy of intravesical gentamicin on the occurrence rate of urinary tract infections and bladder complications in patients after spinal cord injury (SCI), and to assess its effectiveness in…
- Conditions
- Urinary Tract Infections, Spinal Cord Injuries, Spinal Cord Diseases, Neurogenic Bladder
- Trial name
- NCT03503513
- Testing
- Gentamicin Sulfate
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease (COPD
Pulmonary Rehabilitation for Rural Patients With COPD
The purpose of this study is to test the uptake, effectiveness, and patient-caregiver-provider experience of a crucial treatment not provided in rural areas: pulmonary rehabilitation.
- Trial name
- NCT06847061
- Testing
- Pulmonary rehabilitation program
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- Mayo Clinic
Atherosclerosis, Coronary Artery Disease
MARS - Monitored Atherosclerosis Regression Study
The purpose of this study is to determine whether significant alterations in serum lipoproteins as provided by the drug lovastatin can substantially reduce atherosclerosis progression or even induce regression.
- Trial name
- NCT00116870
- Testing
- lovastatin
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypoxia, Erythropoiesis
Effects of Intermittent Hypoxia Training With Iron Supplementation on Red Blood Cells and Iron Levels in Trained Athletes
This study investigates how training under conditions of reduced oxygen (intermittent hypoxia) affects the body's ability to produce red blood cells and manage iron levels, compared to training under normal oxygen conditions.
- Conditions
- Hypoxia, Erythropoiesis, Iron Metabolism Disorders
- Trial name
- IHIT-IRON (NCT07720960)
- Testing
- Control group (CG), Hypoxia group (HG): trained at simulated altitudes between 4,450 and 5,850 m
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Néstor Vicente-Salar
Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Pathological Response to Perioperative FLOT in Gastric Adenocarcinoma
Perioperative chemotherapy with the FLOT regimen (5-fluorouracil, leucovorin, oxaliplatin and docetaxel) is a standard treatment for resectable gastric and gastroesophageal junction adenocarcinoma.
- Conditions
- Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Stomach Neoplasms
- Trial name
- NCT07859254
- Testing
- FLOT Chemotherapy
- Where
- Colombia
- Volunteers
- 90 people
- Sponsor
- Fundación Santa Fe de Bogota
Nasal Bleeding, Nasotracheal Intubation
Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.
- Trial name
- NCT06801522
- Testing
- 0.1% xylometazoline nasal drops, Adrenaline nasal pack
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Papillomavirus Infections
Clinical Effectiveness of PAPILOCARE® in Regression of Cervix HPV Cytological Abnormalities (PAPILOBS GR).
The present study is a multicenter, open, non-interventional, prospective observational clinical study for the evaluation of the effectiveness of Papilocare® (medical device with CE mark) in the regression of cervix cytological…
- Trial name
- PAPILOBSGR (NCT06399341)
- Testing
- Papilocare vaginal gel
- Where
- 4 sites in Greece
- Volunteers
- 524 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Psoriasis
High Dose Risankizumab for Psoriasis
This pilot study explores higher than standard doses of risankizumab for plaque psoriasis, to see effects on resident memory T cells and skin clearance.
- Trial name
- KNOCKOUT (NCT05283135)
- Testing
- risankizumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Medical Research Center
Lateral Elbow Pain, Lateral Epicondylitis
Illness Perception and Treatment Expectations in Lateral Elbow Pain
This cross-sectional, correlational study aims to determine the predictors of illness perception and treatment expectations in adults with chronic lateral elbow pain.
- Conditions
- Lateral Elbow Pain, Lateral Epicondylitis, Tennis Elbow, Chronic Musculoskeletal Pain
- Trial name
- LEP-IPTE (NCT07722845)
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Acibadem University
Spinal Cord Injury at C5-C7 Level With Incomplete Lesion
Use of Implanted Microstimulators for Decreasing Spasticity and Improving Motion Following Spinal Cord Injury
The primary aims of this study are to determine the safety of the RFM System (Alfred Mann Foundation, Santa Clarita, CA) in a patient with incomplete SCI and the effect of the RFM system on lower limb strength and spasticity.
- Trial name
- NCT00781833
- Testing
- Radio Frequency Microstimulator
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Alfred E. Mann Foundation for Scientific Research
HIV-1 Infection
Pilot Peg-Interferon-a2b in Decreasing Viral DNA in HIV
We propose to test our primary hypothesis that treatment with Peg-IFN-α-2b will result in a decrease in integrated HIV DNA in peripheral blood and tissue in chronically HIV-infected immune-reconstituted individuals (see section…
- Trial name
- NCT01935089
- Testing
- Pegylated Interferon alpha 2b
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- The Wistar Institute
Diabetes Mellitus, Atherosclerosis
The Impact of Rosiglitazone on Regression of Atherosclerosis
Cardiovascular events are the leading cause of death in developed countries worldwide, including Taiwan. The disruption of atherosclerotic plaques and the subsequent formation of thrombi are currently recognized as the major…
- Trial name
- NCT00166803
- Testing
- Rosiglitazone
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Prostate Carcinoma
Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy
This clinical trial studies whether cooling the mouth with popsicles (oral cryotherapy) decreases taste changes in prostate cancer patients receiving taxane chemotherapy.
- Trial name
- NCT07218718
- Testing
- Best Practice, Oral Cryotherapy, Survey Administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- City of Hope Medical Center
Coronary Artery Disease, Coronary Atherosclerotic Disease
YN001-004 in Patients With Coronary Atherosclerosis in Australia
This study is to evaluate the efficacy and safety of intravenously administered YN001 in patients with coronary atherosclerosis in Australia.
- Trial name
- NCT06700720
- Testing
- Dose 1 YN001, Dose 2 YN001, Evolocumab
- Where
- 6 sites in Australia
- Volunteers
- 3 people
- Sponsor
- Beijing Inno Medicine Co., Ltd.
Sleep Quality, Intensive Care (ICU)
Predictors of Sleep Quality in Patients Undergoing Open-Heart Surgery
Sleep quality is a complex and multidimensional phenomenon shaped by the interaction of patient characteristics, symptom burden, and environmental factors specific to the intensive care unit environment.
- Conditions
- Sleep Quality, Intensive Care (ICU), Nursing Care
- Trial name
- NCT07755280
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people
- Sponsor
- Aydin Adnan Menderes University
Dental Anxiety, Covid19
Music for Decreasing Dental Anxiety During Oral Surgery in Coronavirus Disease 2019 (COVID-19)
Approximately 100 patients undergoing oral surgery will be divided in 3 groups of musical audition to control anxiety: baroque (N=35), classicism (N=35) and control group (N=30).
- Trial name
- NCT05052034
- Testing
- Music
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Alcohol Drinking, Cannabis Use
Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples
The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples.
- Conditions
- Alcohol Drinking, Cannabis Use, Couples
- Trial name
- NCT06422299
- Testing
- Online, couples-based intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington