Clinical trials: Regression
Gastrointestinal Cancer
Effectiveness of Low Dose Aspirin in Decreasing the Chance Getting Stomach and Intestine Cancer
In this study, researchers wanted to learn more about the effect of Aspirin taken as low dose (75 - 300 mg) in preventing stomach, colorectal and esophagus cancer.
- Trial name
- ENgAGE-HK (NCT04081831)
- Testing
- Acetylsalicylic Acid (Aspirin, BAYE4465)
- Where
- Hong Kong
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Musculoskeletal Pain, Fear of Falling
Free From Pain Exercise Programme Study
To determine the effectiveness of the "Free from Pain" exercise and information programme. The complete programme provides exercises and information for people over the age of 60 to reduce early osteoarthritic and generalised…
- Trial name
- NCT05091671
- Testing
- Free From Pain Exercise Programme Variation 1, Free From Pain Exercise Programme Variation 2
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Talita Cumi Ltd.
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aminoglycoside Toxicity, Acute Kidney Injury
Risk Factors and Machine Learning Model for Aminoglycines Related Acute Kidney Injury
Drug-induced acute kidney injury (D-AKI) can occur after treatment with aminoglycosides. Predicting the risk of D-AKI is important for a tailored prevention and palliation strategy.
- Trial name
- NCT05533593
- Testing
- Aminoglycoside
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Qianfoshan Hospital
Hepatitis B, Chronic
Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based Therapy
Hepatitis B virus (HBV) infection is prevalent across the world. Functional cure is the optimal endpoint of antiviral therapy for chronic hepatitis B virus (HBV) infection.
- Trial name
- NCT06196632
- Testing
- Peginterferon-α; Nucleoside analogs
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Qilu Hospital of Shandong University
Diabetic Retinopathy, Retinal Neovascularization
Krypton-Argon Regression of Neovascularization Study (KARNS)
To evaluate whether red krypton laser treatment is as effective at causing regression of diabetic disc neovascularization as treatment with the blue-green argon laser, when both lasers are used with identical panretinal…
- Conditions
- Diabetic Retinopathy, Retinal Neovascularization, Diabetes Mellitus
- Trial name
- NCT00000153
- Testing
- Blue-Green Argon Laser Treatment, Red Krypton Laser Treatment
- Sponsor
- National Eye Institute (NEI)
Ankylosing Spondylitis, Work Productivity
Work Productivity and Social Activities In Patients With Ankylosing Spondylitis
The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with…
- Trial name
- NCT04749537
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Tooth, Deciduous, Pulpotomy
Risk Factors on the Long-Term Success of Mineral Trioxide Aggregate Pulpotomy
The goal of this observational study is to learn about the long-term results of Mineral Trioxide Aggregate (MTA) pulpotomy in primary molars and the factors that may affect treatment success.
- Conditions
- Tooth, Deciduous, Pulpotomy, Risk Factors, Mineral Trioxide Aggregate (MTA)
- Trial name
- NCT07312539
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sümeyra Akkoç
Neurological Regression, Myoclonus
Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders
Study description: This is a natural history study that will evaluate any patient with enzyme or DNA confirmed GM1 or GM2 gangliosidosis, sialidosis or galactosialidosis.
- Conditions
- Neurological Regression, Myoclonus, Cherry Red Spot, Brain Atrophy
- Trial name
- NCT00029965
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Anxiety
Essential Oils for Electrocautery
The purpose of this study is to assess whether essential oil aromatherapy could improve or eliminate the smell of burnt flesh from electrocautery and subsequently mitigate patient anxiety and discomfort during dermatologic skin…
- Trial name
- NCT04260867
- Testing
- Essential Oil, No Essential Oil
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Loneliness, Anxiety
Is Signposting to Online Peer Support Helpful in Decreasing Loneliness in Parents of Children With Long-term Conditions and Disabilities?
The present study aims to evaluate whether signposting to online peer support will be associated with a significant decrease in self-reported loneliness for parents of children with long-term conditions and disabilities.
- Conditions
- Loneliness, Anxiety, Anxiety Disorder, Depression
- Trial name
- NCT05373121
- Testing
- Online Peer Support
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University College, London
Carotid Atherosclerosis
Sonodynamic Therapy in the Treatment of Carotid Atherosclerosis
Sonodynamic therapy (SDT) is a new treatment for carotid atherosclerotic plaque. The purpose of this study is to evaluate the safety and initial effectiveness of this technique.
- Trial name
- SMART-C (NCT03871725)
- Testing
- Sonodynamic therapy (SDT)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Thyroid Neoplasms, Hypothyroidism
Individual Dosing of Levothyroxine After Thyroidectomy
Recently, Zaborek et al. raised a Poisson regression model for levothyroxine(LT4) dosing scheme to predict individual dose of LT4 after thyroidectomy: daily LT4 dose=e[2.02+0.01(W)-0.0037(A…
- Conditions
- Thyroid Neoplasms, Hypothyroidism, Surgery
- Trial name
- NCT05240911
- Testing
- Levothyroxine Sodium Tablets
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nausea, Postoperative, Vomiting, Postoperative
Decreasing Post-Operative Nausea and Vomiting in the Bariatric Surgical Patient
From the research and current studies, post-operative nausea and vomiting is a common complaint after bariatric surgery. Nausea relief inhalers could improve post-operative nausea and vomiting without the need for further…
- Trial name
- NCT06110416
- Testing
- nausea relief inhaler
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Methodist Health System
End-Stage Renal Disease
Decreasing Depression and Anxiety and Their Effect on QoL of ESRD Patients (End-Stage Renal Disease)
This study evaluates the effect of a single cognitive-behavioral intervention (CBI) in a control group against the same CBI plus the strengthening of resiliency skills in an experimental group, on ESRD patients.
- Trial name
- ESRD (NCT03330938)
- Testing
- CBI and Resilience, Cognitive-behavioral Intervention
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Hospital Civil de Guadalajara
Heart Failure
Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure
The study is to evaluate the safe admission avoidance and the overall economic impact associated with management of worsening HF using the drug-device combination product, the Furoscix Infusor, outside the hospital setting in…
- Trial name
- FREEDOM-HF (NCT03458325)
- Testing
- Furoscix Infusor
- Where
- 8 sites in United States
- Volunteers
- 27 people
- Sponsor
- scPharmaceuticals, Inc.
Aortic Dissection
Logistic Regression of Risk Factor for the 5-year Mortality of Aortic Dissection
The relevant predictive hospital risk factors for 5-year mortality of patients with aortic dissection is untill unlear. The aim of this study is to collect the clinical data of 111 hospitalized patients admitted to hospital from…
- Trial name
- NCT01782534
- Volunteers
- 111 people
- Sponsor
- Central South University
Third Molar Extraction
Decreasing Edema with Platysma Exercises Following Third Molar Extraction Surgery
This study will investigate the effects of a platysma muscle exercise on edema following third molar extraction surgery.
- Trial name
- NCT06761664
- Testing
- Platysma Exercise Group, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Melek Volkan Yazici
Pain
Auranofin in Decreasing Pain in Patients With Paclitaxel-Induced Pain Syndrome
This randomized pilot clinical trial studies whether auranofin will relieve pain following paclitaxel in patients who have previously experienced paclitaxel-induced pain.
- Trial name
- NCT02063698
- Testing
- auranofin, questionnaire administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Emergency Treatment, Telephone Hotlines
Decreasing ED Utilization by Nudging Patients to Call Their Providers
In the present study, patients will be sent a message shortly after completing a medical procedure that informs or reminds them that they can reach out to Geisinger, and how to do it, if they have any medical issues or concerns.
- Trial name
- NCT04567849
- Testing
- message, provider, tele-nurse
- Where
- United States
- Volunteers
- 11,546 people
- Sponsor
- Geisinger Clinic