Clinical trials: Rejuvenation
Injuries to the Wrist and Hand
Use Of Three Commercial Preparations Of Injectable Hyaluronic Acid In Hands Rejuvenation
Assessment of efficacy of hyaluronic acid - Emervel® Volume Lidocaine combined or not with Emervel® Touch and Emervel® Deep Lidocaine combined or not with Emervel® Touch in female patients with loss of fatty tissue in hands.
- Trial name
- NCT01774396
- Testing
- Emervel® Touch, Emervel® Volume Lidocaine and Emervel® Deep Lidocaine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Skin Aging, Skin Rejuvenation
Comparison of the Effects of Carboxytherapy and Radiofrequency on Skin Rejuvenation
Carboxytherapy (CA) refers to the cutaneous and subcutaneous administration of carbon dioxide gas [CO2] for therapeutic purposes.
- Trial name
- NCT01981980
- Testing
- Carboxytherapy, Radiofrequency
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Adriana Clemente Mendonça
Wrinkle, Elastic Skin
Straberi Epistamp Needling Treatment For Skin Rejuvenation
This pilot study will expand knowledge and application needling using the Epistamp device for the improvement of a new vitalized epidermal layer with new vibrant active cells, supported by more robust collagen and elastin fine…
- Conditions
- Wrinkle, Elastic Skin, Collagen Degeneration
- Trial name
- ESAA (NCT04742803)
- Testing
- Straberi Epistamp Microneedling Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universal Skincare Institute
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Vaginal Atrophy, Vaginal Relaxation
Evaluation of Efficacy and Safety of Votiva for Vaginal Rejuvenation
This is a multi-site, randomized, prospective study designed to evaluate the safety and efficacy of the Votiva device headpieces through radiofrequency for vaginal rejuvenation.
- Conditions
- Vaginal Atrophy, Vaginal Relaxation, Stress Urinary Incontinence
- Trial name
- NCT03520426
- Testing
- Votiva RF
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Walden, Jennifer L., M.D.,P.L.L.C.
Subbrow Blepharoplasty;Double Eyelid Surgery； Orbicularis Oculi Muscle
Subbrow Blepharoplasty Combined With Double Eyelid Surgery for Upper Eyelid Rejuvenation in Asian Women
Subbrow blepharoplasty combined with double eyelid surgery excising the subbrow skin and the supratarsal upper eyelid skin, lifting and fixing the OOM flap, meanwhile restoring the natural and symmetrical appearance, is a safe…
- Trial name
- NCT04001660
- Testing
- Subbrow Blepharoplasty Combined with Double Eyelid Surgery
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Stress (Psychology), Stress
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
The purpose of this prospective single-center, blinded*, randomized, proof-of-concept study is to determine whether OnabotulinumtoxinA (BOTOX®) injections will change the level of stress perceived by generally healthy adult…
- Conditions
- Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic
- Trial name
- NCT06778421
- Testing
- Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Facial Plastic Surgery
Enhance Immune Function
The Exploratory Study on the Nicotinamide Mononucleotide (Vital NAD ) to Promote the Rejuvenation of the Peripheral Blood Immune Cells of Adults.
The purpose of this study is to investigate the changes in adult peripheral blood immune cell subpopulations, subpopulations, and cell functional status before and after intervention with Nicotinamide Mononucleotide (Vital NAD )…
- Trial name
- NCT05984550
- Testing
- NMN
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shanghai Cell Therapy Group Co.,Ltd
Infertility, Female, Anovulatory Infertility
Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.
- Conditions
- Infertility, Female, Anovulatory Infertility, Menopause, Amenorrhea
- Trial name
- PRP (NCT03916978)
- Testing
- Autologous PRP intra ovarian infusion, Autologous PFP intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Skin Tightening and Rejuvenation
The Efficacy of Nanofractional Radiofrequency Device in Arm Rejuvenation and Tightening : a Pilot Study
The objective of this study is to evaluate arm rejuvenation and tightening with a nanofractional radiofrequency device, Venus viva, Venus concept, Toronto Canada. We recruit 20 subjects.
- Trial name
- NCT02791620
- Testing
- a nanofractional radiofrequency device
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Decolletage Rejuvenation
Restylane® Skinboosters™ Vital in the décolletage Region
Restylane® Skinboosters™ Vital (SBV) is a smooth formulation without particles, which helps it distribute evenly and smoothly under the skin to aid in rejuvenation.
- Trial name
- NCT04488939
- Testing
- Restylane® Skinboosters™ Vital (SBV)
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Autophagy and Apoptosis in Human Satellite Cells
Rejuvenation of Aged Muscle Stem Cells Through Exercise
The proposed study will establish a newly-identified signaling pathway regulating both autophagy and apoptosis in human satellite cells.
- Trial name
- NCT03473288
- Testing
- Exercise, Sedentary
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Aesthetic, Aesthetic Rejuvenation
Clinical Investigation of the Medical Device "Alexa Volume" for Correction of Midface Volume Loss
This is a post-marketing, open-label, non-comparative, multi-center clinical investigation to evaluate the effectiveness and safety of the medical device "Alexa Volume" (DIACO BIOFARMACEUTICI S.r.l., Italy), based on cross-linked…
- Conditions
- Aesthetic, Aesthetic Rejuvenation, Midface Volumization, Age-related Volume Deficit in the Mid-face
- Trial name
- NCT06984419
- Testing
- Cross-linked hyaluronic acid dermal filler
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments
20 female subjects, between the ages of 25 and 60, who request a full facial rejuvenation treatment, meet all the inclusion and none of the exclusion criteria, and have signed a written informed consent, will be enrolled.
- Trial name
- NCT02551562
- Testing
- NuDerm® System
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Rejuvenation
Study of a Novel Laser for Skin Rejuvenation
Single-center study to evaluate the safety and efficacy of an investigational version of the enlighten™ 670nm laser for photo-rejuvenation.
- Trial name
- NCT02910492
- Testing
- enLighten Laser
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Perioral Wrinkles, Crow's Feet
Prospective, Non-interventional Study Assessing Perioral Rejuvenation Procedure
The goal of this observational study is to learn how a perioral rejuvenation procedure affects perioral line severity and lip volume over time in adults undergoing routine aesthetic treatment in a single clinical center.
- Conditions
- Perioral Wrinkles, Crow's Feet, Lip Volume Enhancement, Lip Aging
- Trial name
- NCT07398768
- Testing
- Saypha® Rich, Saypha® Filler Lidocaine
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yuvell
Lip Rejuvenation
Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions
20 subjects with mild to severe oral commissures or none to severe perioral lines will be enrolled and injected with Restylane® Silk.
- Trial name
- NCT03241862
- Testing
- Restylane® Silk
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Sun-induced Wrinkles
Safety and Efficacy of the Full Face Applications of Variable Doses of a Commercial Botulinum Toxin Type a (Dysport®)
This is an open-label and phase IV study of full face injections of variable doses of botulinum toxin type A (BT-A). As it is an open-label and not blind study, both investigator and subjects will know the injection local and…
- Trial name
- NCT01032954
- Testing
- Botulinum toxin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Wrinkles, Scars
Study of a Novel Microlens Array Device for Skin Rejuvenation
A single-center prospective, open-label uncontrolled pilot study. Subjects will receive laser treatments and will be followed at 12 weeks post-final treatment.
- Trial name
- NCT02888626
- Testing
- Microlens Array
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Aging, Wrinkles
Poly-L-lactic Acid (PLLA) Injection for Neck Skin Laxity: A Pilot Study
Skin aging of the neck commonly leads to wrinkles and skin laxity due to the gradual loss of collagen and structural support in the skin.
- Trial name
- NCT07689344
- Testing
- Poly-L-Lactic Acid (Sculptra) injection
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand