Clinical trials: Remote Ischaemic Preconditioning
Myocardial Injury, Mortality
Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart-Study)
The purpose of this study is to evaluate the effects of Remote Ischaemic Preconditioning on perioperative ischaemic injury in patients undergoing cardiac surgery compared to control intervention.
- Trial name
- NCT01067703
- Testing
- Remote Ischemic Preconditioning
- Where
- 10 sites in Germany
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Schleswig-Holstein
Heart Defects, Congenital
Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery
The purpose of this study is to look at whether the use of a simple technique before surgery, which involves inflating a blood pressure cuff on the infant's leg, can improve development of language, motor and thinking skills at…
- Trial name
- NCT01835392
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Nemours Children's Clinic
Platelet Dysfunction
RIPC and Platelet Activation on Platelet Activation During Cardiopulmonary Bypass
In this study, the investigators are going to investigate the effects of remote ischemic preconditioning on platelet activation in patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- NCT03458351
- Testing
- Remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Myocardial Infarction
Remote Ischemic Preconditioning Combined to Local Ischemic Postconditioning in Acute Myocardial Infarction
RIRE-1 is a randomized, open-label with blinded end-point study that will test the hypothesis that remote ischemic preconditioning initiated at the time of the admission in the cathlab reduces infarct size in ST-segment elevation…
- Trial name
- RIRE-1 (NCT01390142)
- Testing
- Control, RIPer, RIPer + IPost
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Perioperative Myocardial Injury
Perioperative Reduction of Inapparent Myocardial Injury
Recent data suggests that subclinical myocardial injury occurs in patients undergoing major abdominal surgery, and the degree of damage is proportionally linked to morbidity and mortality in the short and medium terms.
- Trial name
- PRIME (NCT01850927)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- London Surgical Research Group
Ischemic Preconditioning
Cutaneous Remote Ischemic Preconditioning in Plastic Surgery
Background: In plastic and reconstructive surgery, free flaps are routinely used for treatment of soft tissue defects. Treatment strategies aim at reducing or preventing flap necrosis by conditioning tissue tolerance against…
- Trial name
- RIPC (NCT01235286)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Cardiac Surgery
Effect of Remote Ischemic Preconditioning on Cognitive Function After Cardiac Surgery
The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cognitive function in patients undergoing cardiac surgery compared to control intervention.
- Trial name
- NCT00877305
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Patrick Meybohm
Aortic Aneurysm, Ischemic Preconditioning
Effect of Remote Ischemic Preconditioning on the Incidence of Contrast Induced Nephropathy in Patients Undergoing EVAR
Introduction: Contrast induced nephropathy (CIN) is a major inconvenience in the use of iodinated contrast media (ICM) and it is associated with a significant increase in morbimortality and cost of hospitalization.
- Trial name
- RIPC-EVAR (NCT05350683)
- Testing
- Remote ischemic preconditioning
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Obliterating Arteriopathy of the Lower Limbs
Protection of Arteritic Patients by Remote Preconditioning
Prospective, monocentric, randomised, double-blind study with 20 patients enrolled to be explored twice through a Cross-over strategy to determine whether remote preconditioning improves arteritic patients' ability to walk.
- Trial name
- PARADIS (NCT01971879)
- Testing
- Remote ischemic preconditioning, Control
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Ischemic Preconditioning
The Biology of Chronic Preconditioning: Genomic and Physiologic Mechanisms of Response
The purpose of this study is to assess the effects of repeated RIPC and exercise, on exercise performance, skeletal muscle responses and circulating cellular and humoral biology in humans
- Trial name
- NCT01164618
- Testing
- Remote ischemic preconditioning (RIPC), Exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Abdominal Aortic Aneurysm, Peripheral Artery Disease
A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery
The purpose of this study is to evaluate the effect of preoperative remote ischaemic preconditioning (RIPC) on organ damage and the functional characteristics of arteries in patients undergoing vascular surgery.
- Conditions
- Abdominal Aortic Aneurysm, Peripheral Artery Disease, Carotid Artery Stenosis
- Trial name
- NCT02689414
- Testing
- Remote ischaemic preconditioning, Control to RIPC
- Where
- Estonia
- Volunteers
- 98 people
- Sponsor
- Tartu University Hospital
Vascular Function
Effects of SIT Combined with Remote Ischemic Preconditioning on Vascular Function in Young Women with Masked Obesity
Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.
- Trial name
- NCT06664281
- Testing
- SIT, SIT combined RIPC
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Unruptured Cerebral Aneurysm
Remote Ischemic PreConditioning (RIPC)
The purpose of this study is to learn about protecting the brain from low blood flow (ischemia) with limb preconditioning. From human studies the investigators know that the brain can be protected from dangerous low blood flow by…
- Trial name
- NCT03814850
- Testing
- Standard Manual Aneroid Sphygmomanometer
- Where
- 2 sites in United States
- Sponsor
- Sebastian Koch
Colon Cancer, Fragility
Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning
This project will examine the efficacy of a simple, cost-effective, non-invasive intervention, called remote ischemic preconditioning (RIPC), to reduce frailty in pre-surgical, frail, elderly patients with colon cancer.
- Conditions
- Colon Cancer, Fragility, Prehabilitation, Surgery
- Trial name
- Prehab (NCT03853473)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Medical College of Wisconsin
Peripheral Arterial Disease
Cardiac Remote Ischemic Preconditioning Before Elective Major Vascular Surgery
Vascular surgery is considered a high-risk operation with an anticipated risk of major cardiovascular complications in excess of 5%.
- Trial name
- CRIPES (NCT01403337)
- Testing
- Ischemic preconditioning, Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Center for Veterans Research and Education
Ischemic Preconditioning, Coronary Disease
Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)
Intermittent arm cuff inflation reduces the extent of heart muscle injury at the time of cardiovascular injury. The intervention is known as remote ischaemic conditioning (RIC) however the mechanisms by which RIC acts are…
- Trial name
- RIC-COR (NCT02666235)
- Testing
- Remote ischaemic conditioning, Arm cuff placement, no inflation;
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS National Waiting Times Centre Board
Stroke
Protective Effects of Remote Limb Ischemic Preconditioning on Acute Cerebral Infarction
Stroke is one of the three leading causes of human death, and a major cause of adult disability. Our pre-clinical studies confirmed that ischemic preconditioning can prevent cerebral infarction.
- Trial name
- NCT01672515
- Testing
- RIPC group, Control group
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Liver Transplanatation
Remote Ischemic Preconditioning in Liver Transplantation
Remote (upper arm) ischemic preconditioning in the donor of living donor liver transplanta to ameliorate the effect of reperfusion injury in recipients.
- Trial name
- RIRI (NCT02534025)
- Testing
- Ischemia preconditioining
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Effectivity of RIPC in Outcomes of TAVI Procedure
Cardioprotective Effect of RIPC in Patients Undergoing TAVI
We aim to investigate whether RIPC (remote ischemic preconditioning) is effective in the TAVI setting to reduce post-procedural myocardial damage and improve patient outcome.
- Trial name
- CARE-TAVI (NCT02283398)
- Testing
- without RIPC, RIPC
- Where
- 3 sites in Germany
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Intact Scaphoid Bone, Intact Metacarpal Bone
Bone Microcirculation After Remote Ischemic Preconditioning
In trauma surgery and hand surgery treatment strategies of none healing bone fractures aim at replacing pseudarthrosis by well vascularized bone and improving microcirculation.
- Conditions
- Intact Scaphoid Bone, Intact Metacarpal Bone, Fractured Scaphoid Bone, Fractured Metacarpal Bone
- Trial name
- NCT02554500
- Testing
- Remote Ischemic Preconditioning (by Blood Pressure Cuff)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein