Clinical trials: Renal Artery Stenosis
Coronary Artery Stenosis
Kidney Damage in Patients With Moderate Fall in eGFR
To compare Iopamidol injection 370 and Iodixanol 320 in evaluating Neutrophil Gelatinase-Associated Lipocalin (NGAL) in patients with moderate fall in eGFR
- Trial name
- NCT01136876
- Testing
- Iopamidol, Iodixanol-320
- Where
- 4 sites in United States, Canada
- Volunteers
- 57 people
- Sponsor
- Bracco Diagnostics, Inc
End-stage Renal Disease
Evaluation of the Radial Artery Deviation And Reimplantation Technique for Primary Hemodialysis Access Creation
The Radial Artery Deviation And Reimplantation (RADAR) technique is a new approach for the construction of hemodialysis arteriovenous fistula.
- Trial name
- RADAR (NCT02728817)
- Testing
- End-cephalic vein to side-radial artery fistula creation, RADAR fistula creation
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hypertension, Renovascular, Renal Artery Stenosis
Cardiovascular, Renal and Metabolic Profile in Patients With Acute Myocardial Infarction (REN-ACS)
Aims assessment of renal artery stenosis incidence in consecutive AMI patients included in the Romanian National Programme of Primary Percutaneous Revascularisation; generating a cardio-renal-metabolic profile in patients with…
- Conditions
- Hypertension, Renovascular, Renal Artery Stenosis, Myocardial Infarction
- Trial name
- REN-ACS (NCT02388139)
- Testing
- renal artery angiography, coronarography, coronary angioplasty
- Where
- Romania
- Volunteers
- 200 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Atherosclerotic Renal Artery Stenosis, Ischemic Nephropathy
MSC for Occlusive Disease of the Kidney
To determine the safety and toxicity of intra-arterial infused autologous adipose derived mesenchymal stromal (stem) cells in patients with vascular occlusive disease of the kidney.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Ischemic Nephropathy, Renovascular Hypertension
- Trial name
- NCT01840540
- Testing
- Arterial infusion of autologous mesenchymal stem cells
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Renal Artery Stenosis
A Safety & Efficacy Clinical Study to Evaluate the Narrowing of the Renal Arteries While Using Gadodiamide
Magnetic Resonance Angiography (MRA) is an examination similar to Magnetic Resonance Imaging (MRI) which uses a magnetic field and a contrast medium when needed to visualize blood flow in the arterial vessels throughout the body.
- Trial name
- NCT00209391
- Testing
- Gadodiamide Injection
- Where
- Germany
- Volunteers
- 395 people
- Sponsor
- GE Healthcare
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Renal Artery Stenosis
Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis
Renal artery stenosis (RAS) usually refers to a disease of the large extra-renal arterial vessels and most frequently is caused by atherosclerotic obstructions.
- Trial name
- NCT00711984
- Testing
- Herkulink renal artery Stent, best medical therapy
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
High blood pressure (hypertension) is a leading cause of kidney damage, but detecting early kidney changes remains challenging with currently available tools.
- Conditions
- Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism, Arterial Stenosis
- Trial name
- K-STRESS (NCT07914075)
- Where
- Italy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Renal Failure, Arteriovenous Fistula
Surveillance and Proactive Intervention for Dialysis Access
Newly formed dialysis fistulae can often fail, and failure is usually due to narrowing of the blood vessels. Methods of detecting narrowing are available and, more importantly, can detect narrowings before a fistula fails.
- Trial name
- SPIDA (NCT01391975)
- Testing
- Active ultrasound surveillance of fistula and proactive treatment of stenosis
- Where
- United Kingdom
- Sponsor
- University of Hull
Renovascular Hypertension, Renovascular Hypertension With Renal Failure
Effects of Percutaneous Transluminal Renal Angioplasty of Atherosclerotic Renal Artery Stenosis in High-Risk Patients.
The goal of this clinical trial is to investigate whether percutaneous transluminal renal angioplasty (PTRA) with stent placement of atherosclerotic renal artery stenosis is beneficial in high-risk patients selected according to…
- Conditions
- Renovascular Hypertension, Renovascular Hypertension With Renal Failure, Heart Failure, Renal Artery Stenosis Atherosclerotic
- Trial name
- DAN-PTRAII (NCT05834803)
- Testing
- Optimal medical therapy (OMT), Catheter-based angiography, Measurement of translesional pressure gradients
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Healthy, Renovascular Hypertension
Magnetic Resonance Imaging for Evaluating Kidney Function
Renovascular hypertension (RVH) is a potentially curable disease affecting 0.5-5 percent of patients with hypertension. The current diagnostic work-up of RVH involves a complex algorithm which includes doppler ultrasound…
- Trial name
- NCT00006173
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Renal Artery Stenosis
Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis
The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal…
- Trial name
- NCT05603221
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Renal Artery Stenosis
Ciclosporin A Preconditioning for Renal Artery Stenosis
Renal artery stenosis is one the leading cause of secondary hypertension. Previous randomized controlled trials in humans have failed to demonstrate an improvement of renal function after stenosis dilation, probably because of a…
- Trial name
- CicloSAAR (NCT03382301)
- Testing
- Ciclosporin A preconditioning before renal artery stenosis dilation, NaCl preconditioning before renal artery stenosis dilation
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Takayasu Arteritis
Drug-coated Balloon for Takayasu Arteritis Associated Renal Artery Stenosis
Takayasu arteritis associated renal artery stenosis (TARAS) is the biggest cause of hypertension in young people <40 years old. Hypertension caused by renal artery stenosis is usually hard to control in spite of two or more…
- Trial name
- NCT04137614
- Testing
- Drug coated balloon (DCB), Digital substraction angiography (DSA)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
Atherosclerotic Renal Artery Stenosis
The Evaluation Studies of Curative Effect of Fu-zheng-qu-zhuo Oral Liquid in Treatment of Ischemic Nephropathy
Background: Since evidence show that renal-artery stenting did not confer a significant benefit with respect to the prevention of clinical events when added to comprehensive, multifactorial medical therapy in people with…
- Trial name
- NCT02044835
- Testing
- Fu-zheng-qu-zhuo oral liquid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Renal Transplant
Efficacy and Safety Study of Aspirin for the Prevention of Renal Artery Stenosis in Renal Transplantation Recipients
The anastomotic and peripheral stenosis of the transplanted kidney artery is one of the most important causes of graft failure in renal transplantation.
- Trial name
- NCT04260828
- Testing
- Aspirin 100mg
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Henan Provincial People's Hospital
Renal Artery Stenosis
Magnevist® Injection-enhanced MRA Compared to Non Contrast MRA for the Detection of Stenosis of the Renal Arteries
The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of Magnevist (the study drug) used for MRI of the renal arteries.
- Trial name
- NCT00310557
- Testing
- Gadopentetate dimeglumine (Magnevist)
- Volunteers
- 116 people
- Sponsor
- Bayer
Renal Artery Stenosis
Formula PTX Renal Stent Clinical Study
The purpose of the study is to evaluate the safety and effectiveness of the PTX-coating on the Formula PTX Balloon-Expandable Stent in treatment of renal artery stenosis.
- Trial name
- NCT01057316
- Testing
- Formula PTX Stent - Dose 1, Formula PTX Stent - Dose 2, Formula PTX Stent - Dose 3
- Where
- 12 sites in Czechia, France and 2 more
- Volunteers
- 120 people
- Sponsor
- Cook Group Incorporated
Renal Artery Stenosis, Ischemic Nephropathy
Hypoxia and Inflammatory Injury in Human Renovascular Hypertension
Current treatments for ARAS based on restoring blood flow alone have been unsuccessful at recovering kidney function. For this reason we are studying a stem cell product called "mesenchymal stem cells" or MSC.
- Conditions
- Renal Artery Stenosis, Ischemic Nephropathy, Renovascular Disease, Chronic Kidney Disease
- Trial name
- NCT02266394
- Testing
- Mesenchymal stem cell, Mesenchymal stem cell delivery with stent placement
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Mayo Clinic
Transplant Renal Artery Stenosis
Transplant Renal Artery Stenosis: Observation Versus Stenting
Transplant renal artery stenosis (TRAS) is abnormal narrowing of the main blood vessel to the kidney transplant and has historically been considered a surgical complication.
- Trial name
- TRASOS (NCT05046496)
- Testing
- Intra-arterial digital subtraction angiography
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Imperial College Healthcare NHS Trust