Clinical trials: Renal Cyst
Primary Aldosteronism
Renal Cysts and Primary Aldosteronism
During routine subtyping of confirmed primary aldosteronism by adrenal vein sampling extra plasma samples are drawn from both renal veins and from inferior vena cava.
- Trial name
- NCT05435703
- Where
- Finland
- Volunteers
- 115 people
- Sponsor
- Tampere University Hospital
Kidney Neoplasms, Kidney Cancer
Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer
This study will investigate the genetic cause of Birt Hogg-Dube (BHD) syndrome and the relationship of this disorder to kidney cancer.
- Conditions
- Kidney Neoplasms, Kidney Cancer, Pneumothorax, FLCN Protein, Human
- Trial name
- NCT00033137
- Where
- United States
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD
The aim of this study is to identify families with ADPKD , characterize the phenotype and screen for mutations in known genes (PKD1 and PKD2, and then HNF1b and UMOD in PKD1 PKD2 negative carriers).
- Trial name
- GeneQuest (NCT02112136)
- Testing
- Blood Collection
- Where
- 25 sites in France
- Volunteers
- 1,450 people
- Sponsor
- University Hospital, Brest
Autosomal Recessive Polycystic Kidney (ARPKD)
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
To evaluate the pharmacodynamics and safety of tolvaptan in pediatric subjects with ARPKD
- Trial name
- NCT04782258
- Testing
- Tolvaptan Suspension, Tolvaptan Tablets
- Where
- 23 sites in United States, Belgium and 4 more
- Volunteers
- 20 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Ovarian Cysts, Chronic Renal Insufficiency
Anti-inflammatory Cells in Peritoneal Cavity
Some subsets of lymphocytes are able to inhibit immune response and thus, could be used to control auto-immune diseases and transplant reject.
- Trial name
- NCT03189316
- Testing
- peritoneal fluid and blood sample
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Ovarian Cyst
Effects of Adrenergic Drugs on the Fluid Balance During Surgery
The aim this study was to examine to what degree the slow turnover of lactated Ringer's solution during anesthesia and surgery can be prevented by infusing esmolol (a ß1-receptor blocker) or phenylephrine in patients undergoing…
- Trial name
- NCT01431612
- Testing
- Esmolol administration, Phenylephrine infusion, Lactated Ringer´s solution
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sodertalje Hospital
Complex Renal Cyst
Surveillance of Complex Renal Cysts - The SOCRATIC Study
One third of individuals aged >60 years will be diagnosed with at least one renal cyst following abdominal imaging. These cystic lesions are categorized according to the Bosniak classification which categorizes cysts according to…
- Trial name
- SOCRATIC (NCT04558593)
- Testing
- Active surveillance, Surgery
- Where
- 18 sites in Canada, France
- Volunteers
- 330 people
- Sponsor
- Université de Sherbrooke
Renal Cell Carcinoma (RCC), Renal Cyst
The CT-based Deep Learning Model Predicts Complications in Partial Nephrectomy
The investigators combine radiomics and deep learning to analyze the lesions more thoroughly, aiming for a more accurate prediction of complications in partial nephrectomy, and compare this approach with traditional models.
- Trial name
- NCT06876584
- Where
- China
- Volunteers
- 1,474 people
- Sponsor
- Du Lingzhi
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
ccRCC, Complex Renal Cyst
68Ga-NYM096 PET/ CT for the Detection of ccRCC in Presurgical Patients With Complex Cystic Renal Leision
This is a prospective, single-center, single-arm, diagnostic phase 2 study aimed at evaluating the sensitivity and specificity of 68Ga-NYM096 PET/CT in detecting clear cell renal cell carcinoma (ccRCC) in patients with complex…
- Trial name
- NYCRCCL (NCT06949215)
- Testing
- 68Ga-NYM096 PET/CT
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Von Hippel-Lindau Syndrome, Renal Cell Carcinoma
Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow
The goal of this clinical research study is to learn if sunitinib malate (SU011248) can help to control VHL. The safety of this drug will also be studied.
- Conditions
- Von Hippel-Lindau Syndrome, Renal Cell Carcinoma, Hemangioblastoma
- Trial name
- NCT00330564
- Testing
- SU011248
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center
Renal Cyst
Surveillance of Complex Renal Cysts - the SOCRATIC Pilot Study
One third of individuals aged >60 years will be diagnosed with at least one renal cyst following abdominal imaging. These cystic lesions are categorized according to the Bosniak classification which categorizes cysts according to…
- Trial name
- SOCRATICp (NCT04079764)
- Where
- 3 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Circumcision, Hydrocelectomy
Enhanced Recovery After Urologic Surgery
This clinical trial aims to investigate the analgesic efficacy of several perioperative pain management strategies-specifically, epidural analgesia, paravertebral blockade, transversus abdominis plane (TAP) block, intravenous…
- Conditions
- Circumcision, Hydrocelectomy, Hernia, Renal Cyst
- Trial name
- NCT06789744
- Testing
- General Anesthesia (GA), Epidural Analgesia( 0.2% ropivacaine), Paravertebral block ( liposomal bupivacaine 133 mg or 0.2% ropivacaine)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xiaguang Duan
Renal Cyst Complex
The Potential of Radiomics to Differentiate Between Malignant and Benign Bosniak 3 Renal Cysts.
More than 200,000 new cases of renal cancer are diagnosed in the world each year, with more than 63,000 new cases in Europe alone.
- Trial name
- BIII (NCT03552497)
- Testing
- Radiomics
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Maastricht University
Liver Cyst, Polycystic Liver Disease
Assessment of Treatment With Laparoscopic Fenestration or Aspiration Sclerotherapy for Large Symptomatic Hepatic Cysts
Patients with large hepatic cysts (> 5cm) may develop symptoms. These can be captured with the polycystic liver disease questionnaire (PLD-Q).
- Conditions
- Liver Cyst, Polycystic Liver Disease, Autosomal Dominant Polycystic Kidney, Autosomal Dominant Polycystic Liver Disease
- Trial name
- ATLAS (NCT05500157)
- Testing
- aspiration sclerotherapy versus laparoscopic fenestration
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Laparoscopic Marsupialization of Renal Cyst
Prophylactic Effects of Ondansetron, Ramosetron, and Palonosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Urologic Laparoscopic Surgery
The aim of this prospective randomized controlled study was to compare the prophylactic effects of intravenous single dose of ondansetron, ramosetron, and palonosetron on PCA-related nausea and vomiting after urologic…
- Trial name
- NCT01169805
- Testing
- Ondansetron, Ramosetron, Palonosetron
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Yonsei University
Nephritis, Interstitial, Chronic Renal Failure
Hereditary Tubulointerstitial Nephritis
The aim of this study is to identify families with hereditary chronic tubulointerstitial renal diseases , characterize the phenotype and screen for mutations in known genesis (UMOD, REN, TCF2, NPHP1).
- Conditions
- Nephritis, Interstitial, Chronic Renal Failure, Gout, Renal Cysts
- Trial name
- NTIH (NCT01312727)
- Testing
- Blood and urine sample collections
- Where
- France
- Volunteers
- 225 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Hepato/Renal Fibrocystic Disease, Autosomal Recessive Polycystic Kidney Disease
ARPKD Database Study
Hepato-renal fibrocystic diseases (HRFD) is a term developed that encompasses rare diseases such as Autosomal Recessive Polycystic Kidney Disease (ARPKD), and other diseases with common features (Joubert syndrome, Bardet Biedl…
- Conditions
- Hepato/Renal Fibrocystic Disease, Autosomal Recessive Polycystic Kidney Disease, Joubert Syndrome, Bardet Biedl Syndrome
- Trial name
- ARPKD (NCT01401998)
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Philadelphia
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University