Clinical trials: Renal Cyst
Polycystic Ovary Syndrome
Effects of Flutamide on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the major cause of infertility in the United States. Many women with PCOS demonstrate insulin resistance and a compensatory hyperinsulinemia.This is due to both an intrinsic form of insulin…
- Trial name
- PCOS (NCT00729560)
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Pneumonia, Pleural Effusion
Evaluation of Ultra-portable Ultrasound in General Practice
This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months.
- Conditions
- Pneumonia, Pleural Effusion, Renal Colic, Hepatic Colic or Cholecystitis
- Trial name
- EPEMedG (NCT04127149)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 166 people
- Sponsor
- Hospices Civils de Lyon
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in…
- Trial name
- ADPKD (NCT06786260)
- Testing
- Interventional Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Loma Linda University
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Urothelial Carcinoma, Renal Cell Carcinoma
Prospective Trial for Examining Hematuria Using Computed Tomography
The primary objective is to evaluate whether one-phase nephrographic CT (experimental) is sufficient to detect urothelial cell carcinoma in patients with hematuria compared to the traditional four-phase CT (control).
- Conditions
- Urothelial Carcinoma, Renal Cell Carcinoma, Renal Cyst, Renal Stone
- Trial name
- PROTEHCT (NCT04077359)
- Testing
- CT
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Complex Renal Cyst
Contrast-enhanced Ultrasound for the Evaluation of Complex Renal Cysts
Complex renal cysts are often incidentally detected on imaging. The differential diagnosis of the complex renal cyst includes various benign cystic lesions, which are based on the Bosniak classification scheme.
- Trial name
- NCT01353521
- Testing
- Contrast-enhanced ultrasound
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Cystic Renal Diseases, Kidney Neoplasms
Evaluation of Complex Renal Cyst With CEUS/Functional MRI Versus CT
The primary concern in complex renal cysts (CRC) with malignant potential is the accurate diagnosis and characterization. Patients with CRC have to undergo frequent imaging surveillance (every 6-12 Mo), in which the progression…
- Trial name
- NCT02371551
- Testing
- Blood/urine sampling, Conventional routine CT examination, Contrast-enhanced renal ultrasonography (CEUS)
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Polycystic Ovary Syndrome
Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS)
Our hypothesis is that hyperinsulinemia increases the renal clearance of D-chiro-inositol (DCI) in women with polycystic ovary syndrome (PCOS) and that this leads to a reduction in circulating insulin-stimulated…
- Trial name
- PCOS (NCT00868140)
- Testing
- pioglitazone
- Where
- 2 sites in United States, Venezuela
- Volunteers
- 51 people
- Sponsor
- Virginia Commonwealth University
Vascular Postoperative Complications, Urological System Complication of Procedure
Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation
Globally there have been about 45,000 kidney transplants last year. Currently, the overall survival of renal transplant receptors is 95% in the first year and 85% at 5 years.
- Conditions
- Vascular Postoperative Complications, Urological System Complication of Procedure, Lymphocele, Postoperative Infection
- Trial name
- NCT01631448
- Testing
- Fibrin Glue
- Where
- 2 sites in Mexico
- Volunteers
- 152 people
- Sponsor
- Alejandro Gonzalez-Ojeda
Polycystic Kidney, Autosomal Dominant
Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease
This study will test to see if metformin is safe and if it is tolerated compared to placebo in adult Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients with beginning stages of chronic kidney disease.
- Trial name
- TAME (NCT02656017)
- Testing
- Metformin
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Kyongtae Ty Bae, M.D., Ph.D.
Simple Renal Cyst, Renal Function Disorder
Influence of Simple Renal Cysts on Renal Function
This is a prospective, cohort, randomized clinical trial examining the effect of simple renal cysts on renal function.
- Trial name
- NCT05134077
- Testing
- CT scan with contrast, Nephroscintigraphy
- Volunteers
- 120 people
- Sponsor
- Moscow State University of Medicine and Dentistry
CT KUB, Renal Cyst
CT KUB in Renal Cysts
1. Primary (main): 1. Determine the diagnostic accuracy of CT KUB in differentiating between benign and suspicious renal cysts according to the Bosniak classification. 2. Secondary (subsidiary): 1.
- Trial name
- NCT07187791
- Testing
- CT scan
- Volunteers
- 200 people
- Sponsor
- Assiut University
Carcinoma, Renal Cell, Renal Malignant Tumor
a Prospective Trial Comparing Robot-assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
In this trial the investigators want to examine and compare oncological and surgical outcomes of two surgical techniques in a prospective, randomised, single-blind trial.
- Conditions
- Carcinoma, Renal Cell, Renal Malignant Tumor, Renal Cyst, Renal Tumor
- Trial name
- NCT03900364
- Testing
- partial nephrectomy
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Salzburger Landeskliniken
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
The primary objective of this study is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney disease (ARPKD)
- Trial name
- NCT04786574
- Testing
- Tolvaptan (OPC-41061)
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Kidney Neoplasm, Cysts
Detection of Renal Malignancy of Complicated Renal Cysts
The aim of this study was to show additional diagnostic criteria of computed tomography (CT) scan to diagnose and predict the detection and recurrence of cystic renal cell carcinoma in the patients with complicated renal cysts.
- Conditions
- Kidney Neoplasm, Cysts, Carcinoma, Renal Cell
- Trial name
- NCT01087060
- Testing
- partial or radical nephrectomy
- Where
- South Korea
- Volunteers
- 269 people
- Sponsor
- Seoul National University Hospital
Renal Cell Carcinoma, Adrenal Tumor
The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery
A single-arm clinical trial was designed in this study. The surgeon will perform urological telesurgery for patients using Chinese domestically produced "MicroHand S" surgical robot system.
- Conditions
- Renal Cell Carcinoma, Adrenal Tumor, Nonfunctioning Kidney, Renal Pelvis Carcinoma
- Trial name
- NCT05739812
- Testing
- telesurgery by domestic surgical robot
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Polycystic Ovary Syndrome, Urine Albumin \(UAlb\)
Urine Albumin/Creatinine Ratio and Renal Function Differences in Phenotypes of Polycystic Ovary Syndrome.
Since there are different metabolic effects in different phenotypes of polycystic ovary syndrome (PCOS); in this study; the investigators aimed to investigate whether there is a difference between glomerular filtration rate…
- Conditions
- Polycystic Ovary Syndrome, Urine Albumin \(UAlb\), Urine Creatinine \(UCr\), Glomerular Filtration Rate
- Trial name
- NCT07441811
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Uşak University
Renal Cell Carcinoma, Renal Cysts
Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial
To compare SBDECT with standard Triple Phase Multi-Detector CT (TPMDCT) in renal mass evaluation in terms of appropriateness of treatment received after diagnosis. To determine SBDECT diagnostic accuracy.
- Conditions
- Renal Cell Carcinoma, Renal Cysts, Transitional Cell Carcinoma, AML
- Trial name
- NCT02160600
- Testing
- Standard multiphase CT, split bolus Dual energy CT
- Where
- India
- Volunteers
- 124 people
- Sponsor
- All India Institute of Medical Sciences
Simple Renal Cyst
Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing
Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.
- Trial name
- NCT03259594
- Testing
- Laparoscopic deroofing, 100 g of amino acids supplementation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- ou tongwen