Clinical trials: Renal Failure, End-stage
End Stage Renal Disease, Renal Anemia
Assessment of an Anemia Model Predictive Controller for Anemia Management in Hemodialysis Patients
The purpose of this randomized, controlled pilot study is to evaluate the performance of this novel Anemia Controller (vis-à-vis standard of care) for anemia management in hemodialysis patients.
- Conditions
- End Stage Renal Disease, Renal Anemia, Chronic Kidney Diseases
- Trial name
- NCT04360902
- Testing
- Anemia Controller
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Renal Research Institute
Respiratory Failure, Shock
Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care
End-stage renal disease (ESRD) is an important risk factor for coronary and valvular cardiac disease leading to cardiac surgery.
- Conditions
- Respiratory Failure, Shock, Coagulopathy
- Trial name
- NCT04705701
- Testing
- Hemodialysis
- Sponsor
- Northwell Health
Fatigue, End Stage Renal Disease
Fatigue in Chronic Haemodialysis Patients: an Experience Sampling Method Study
To investigate the course and diurnal change of fatigue symptoms and haemodialysis related symptoms in chronic haemodialysis patients, its relation to haemodialysis treatment and the association with other factors by implementing…
- Trial name
- FatHoM (NCT04049773)
- Testing
- haemodialysis
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Zuyderland Medisch Centrum
End Stage Chronic Renal Failure, Myofacial Pain
The Herbal Acupoint Patch for Dialysis Patient With Fistula-related Pain
To evaluate the effect of a traditional Chinese medicine (TCM) intervention on pain relief, mood and quality of life (QOL) in hemodialytic patients at a dialysis center in Southern Taiwan.
- Trial name
- Fistula Pain (NCT07380581)
- Testing
- Artemisias-ginger patch (AGP)
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chang Gung Memorial Hospital
Kidney Failure, Chronic
A Study of Obinutuzumab to Evaluate Safety and Tolerability in Hypersensitized Adult Participants With End Stage Renal Disease Awaiting Transplantation
This is a Phase Ib, open-label study of single and repeat doses of obinutuzumab administered as intravenous (IV) infusion in adults with end stage renal disease (ESRD).
- Trial name
- NCT02586051
- Testing
- Obinutuzumab, Intravenous Immunoglobulin
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia
Cognitive Impairment, End Stage Renal Disease
A Study to Assess the Tolerability and Efficacy of AKST1210 in Patients on Hemodialysis With Cognitive Impairment
This study will evaluate the tolerability, feasibility, and efficacy of the AKST1210 column in subjects with end-stage renal disease with cognitive impairment (ESRD-CI) undergoing hemodialysis 3 times per week.
- Trial name
- NCT04527328
- Testing
- AKST1210, Hemodialysis
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alkahest, Inc.
Chronic Renal Failure
FGF23 Reduction : Efficacy of a New Phosphate Binder in CHronic Kidney Disease
The purpose of this study is to evaluate in Chronic Kidney Disease (CKD) patients not on dialysis and who have an Fibroblast growth factor 23 (FGF23) serum levels elevated, the effect of non calcic phosphate binder: sevelamer…
- Trial name
- FRENCH (NCT01220843)
- Testing
- Sevelamer carbonate
- Where
- 15 sites in France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
End Stage Renal Disease, Living Donor Kidney Transplantation
Social Networks and Renal Education: Promoting Transplantation
There are significant and persistent disparities in access to kidney transplantation and as a result most patients with end stage renal disease receive hemodialysis (HD).
- Conditions
- End Stage Renal Disease, Living Donor Kidney Transplantation, Renal Dialysis
- Trial name
- SNARE (NCT03536858)
- Testing
- COACH (Communicating about Choices in Transplantation)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Temple University
Staphylococcal Infections, Chronic Kidney Failure
Evaluation of Manufacturing Lot of StaphVAX
This study answers a U.S. Food and Drug Administration requirement for evaluation in people of a manufacturing lot of vaccine. Subjects receive one dose of one lot of vaccine.
- Trial name
- NCT00211900
- Testing
- S. aureus Type 5 & 8 Capsular Polysaccharide Vaccine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Nabi Biopharmaceuticals
End Stage Renal Disease, Hemolysis
Ventilatory Functions and Physical Intolerance in ESRD Adolescents: Response to Program of Walking With Dogs
adolescents with chronic renal failure going on hemodialysis usually complain many problems including compromised ventilation, early fatigue, early physical intolerance, and bad life quality.
- Trial name
- NCT06861816
- Testing
- incentive spirometer and walking with dog, training by incentive spirometer only
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Kidney Failure, Chronic, End-Stage Renal Disease
Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™
The purpose of this study is to determine whether or not nocturnal hemodialysis is equivalent to short daily hemodialysis on a per treatment basis, using the NxStage System One in the home setting.
- Trial name
- NCT00667511
- Testing
- NxStage System One
- Where
- 9 sites in United States
- Volunteers
- 58 people
- Sponsor
- NxStage Medical
End Stage Renal Disease, Left Ventricular Hypertrophy
Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study
Kidney patients on dialysis commonly die because of heart disease. One of the biggest problems in their hearts is that the muscle wall of the heart thickens. This makes it less efficient.
- Trial name
- Altered (NCT01951404)
- Testing
- Allopurinol
- Where
- 3 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Dundee
End-stage Renal Disease
French Renal Epidemiology and Information Network (REIN) Registry
The Renal Epidemiology and Information Network (REIN) Registry was created in 2002 (after study pilot in 2001) to contribute to the development and evaluation of health strategies aiming at improving prevention and management of…
- Trial name
- REIN-LOR (NCT03967808)
- Where
- France
- Volunteers
- 6,000 people
- Sponsor
- Central Hospital, Nancy, France
End Stage Renal Disease
A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients
This is a pilot study intended to gather data in order to inform future studies about the role of feedback as an incentive for increasing levels of physical activity which could improve health in hemodialysis patients.
- Trial name
- IAM (NCT02320513)
- Testing
- Wearing activty monitoring device (Fitbit Flex), Fitbit Flex
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Renal Research Institute
End Stage Renal Disease, Endothelial Dysfunction
Cocoa Flavanols in Renal Disease
Purpose of the study is to characterize the potential acute and long-term improvement of dietary flavanols on vascular function in patients with end-stage renal disease (ESRD).
- Trial name
- NCT01412320
- Testing
- Cocoa
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
End-Stage Kidney Disease
Incremental Hemodialysis: The TwoPlus Trial
This study is to prospectively compare clinical effectiveness between clinically- matched incremental hemodialysis and conventional hemodialysis in patients with incident kidney dysfunction requiring dialysis and residual kidney…
- Trial name
- NCT05828823
- Testing
- Hemodialysis twice weekly, Hemodialysis thrice weekly
- Where
- 10 sites in United States
- Volunteers
- 350 people
- Sponsor
- Wake Forest University Health Sciences
Hyperparathyroidism, Secondary, Kidney Failure, Chronic
Hyperparathyroidism and Dialysis Adequacy in Hemodialysis Patients
This cross-sectional study aims to determine the prevalence of secondary hyperparathyroidism among end-stage renal disease patients on regular hemodialysis and to evaluate its relationship with dialysis adequacy at Assiut…
- Conditions
- Hyperparathyroidism, Secondary, Kidney Failure, Chronic, Chronic Kidney Diseases
- Trial name
- NCT07820150
- Volunteers
- 130 people
- Sponsor
- Assiut University
Chronic Renal Failure With Uremic Nephropathy
Studies in Patients With Multiple Myeloma and Renal Failure Due to Myeloma Cast Nephropathy
MYRE is a phase III multicentric controlled national clinical trial conducted in patients with multiple myeloma and renal failure related to myeloma cast nephropathy (MCN).
- Trial name
- MYRE (NCT01208818)
- Testing
- Cyclophosphamide + Bortezomib + Dexamethasone regimen, Bortezomib +Dexamethasone regimen, HCO group
- Where
- France
- Volunteers
- 284 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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