Clinical trials: Renal Failure, End-stage
End Stage Renal Disease
The Measurement of Insulin Resistance in Peritoneal Dialysis Patients
The goal of this study is to examine the relevance of insulin resistance in peritoneal dialysis (PD) patients as well as the means to improve this metabolic derangement.
- Trial name
- NCT01119196
- Testing
- Icodextrin dialysate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University
Anemia, Kidney Failure, Chronic
Study of the Efficacy of Darbepoetin Alfa in the Treatment of Renal Anemia
Anaemia is a common consequence of chronic renal failure. Darbepoetin alfa is a unique erythropoietic protein that stimulates erythropoiesis by the same mechanism as endogenous erythropietin and conventional recombinant human…
- Conditions
- Anemia, Kidney Failure, Chronic, Peritoneal Dialysis, Continuous Ambulatory
- Trial name
- NCT00563446
- Testing
- Darbepoetin alfa
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Hospital Authority, Hong Kong
End Stage Renal Failure on Dialysis
Hemodialysis Blood Flow and Urea Clearance
The study purpose is to determine whether two different hemodialysis blood flow rates each meet national dialysis standards for urea clearance. Urea is used as the primary marker of dialysis adequacy.
- Trial name
- NCT02484118
- Testing
- Hemodialysis blood flow
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
End Stage Renal Disease, Kidney Transplant
A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients
This study will enroll individuals who have end stage renal disease and who are undergoing a solitary kidney transplant. This study is investigating/evaluating the safety and effectiveness of collecting, expanding and infusing a…
- Trial name
- NCT03284242
- Testing
- Treg
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Roberto Gedaly
Chronic Kidney Diseases
Impact of Dapagliflozin on Intestinal Microbiota Composition and on the Metabolites Derived From the Intestinal Microbiota in Non-diabetic Chronic Renal Failure Patients
Chronic kidney disease (CKD) is a common disease affecting 10-12% of the adult population and characterize with high-risk cardiovascular morbidity and mortality with progression of CKD.
- Trial name
- DAPA-GUT (NCT05965440)
- Testing
- impact of Dapagliflozin on Intestinal Microbiota on chronic renal failure patients
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Disease on Dialysis
Intradialytic Kinetics of Cardiac Biomarkers During Hemodialysis and Hemodiafiltration
This randomized, crossover study aims to investigate the intradialytic kinetics of selected cardiac biomarkers in patients with end-stage renal disease treated with dialysis.
- Trial name
- NCT06526702
- Testing
- High-flux hemodialysis, Post-dilution hemodiafiltration
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Aalborg University Hospital
End Stage Renal Disease
Research Study Evaluating Cinacalcet for Patients With End Stage Renal Disease (ESRD)
The purpose of this study is to observe the effects of a treatment strategy that incorporates cinacalcet HCl into the management of secondary hyperparathyroidism (HPT) in subjects with ESRD receiving hemodialysis, on bio-intact…
- Trial name
- NCT00113945
- Testing
- Cinacalcet
- Volunteers
- 360 people
- Sponsor
- Amgen
Renal Injury, Acute
Acute Kidney Injury : Long-term Renal and Cardiovascular Prognosis and Biomarker-based Risk Assessment
Patients who develop severe acute kidney injury (AKI) in intensive care remain at increased long-term risk of mortality, major cardiovascular events, and chronic renal complications, including prolonged dependence on renal…
- Trial name
- AKIRA (NCT07596407)
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Disease Requiring Chronic Dialysis
Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis
Individuals with kidney failure receiving maintenance hemodialysis (HD) have high mortality rates, driven largely by cardiovascular causes.
- Trial name
- NCT04622709
- Testing
- Furosemide (loop diuretic) Tablets
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of North Carolina, Chapel Hill
End Stage Renal Disease
Bioimpedance-guided Fluid Management in Chronic Peritoneal Dialysis Patients.
Peritoneal dialysis (PD) is one of established treatments in the end stage renal disease patients. Volume overload is a predictor of mortality in PD patients.
- Trial name
- NCT03004963
- Testing
- Body composition monitor, clinical indexes
- Where
- China
- Volunteers
- 213 people
- Sponsor
- RenJi Hospital
End Stage Renal Disease, Kidney Failure
Using Shared Decision Making to Improve Kidney Transplantation Rates
The goal of this clinical trial is to increase shared decision-making between dialysis providers and patients in order to increase patients' probability of transplantation and to reduce socioeconomic/racial disparities in access…
- Trial name
- NCT06141499
- Testing
- Provider educational materials, Patient letters
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Columbia University
Fabry Disease, End Stage Renal Disease
Study of the Prevalence of Fabry Disease in French Dialysis Patients
Fabry Disease (FD) is a rare genetic lysosomal storage disease including an X-linked mutation and characterized by an alpha-galactosidase A (GLA) deficiency.
- Conditions
- Fabry Disease, End Stage Renal Disease, Renal Dialysis
- Trial name
- FABRYDIAL (NCT02843334)
- Testing
- Dried blood spot (DBS) sampling
- Where
- 5 sites in France
- Volunteers
- 6,000 people
- Sponsor
- Hospices Civils de Lyon
Hemodialysis Complication, Anticoagulants
Variability in Micro-CT Imaging Results to Quantify Dialyzer Clotting
Different cross-over studies have been performed investigating dialyzer fiber patency in different dialysis setups. Herewith, post dialysis micro computed tomography (CT) images of the dialyzer were compared.
- Trial name
- ClotVar (NCT06140563)
- Testing
- anticoagulation dosing
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent
Palliative Care, Kidney Failure, Chronic
A Communication Tool to Assist Older Adults Facing Dialysis Choices
The purpose of this study is to test the effect of the "Best Case/Worse Case" (BC/WC) communication tool on receipt of palliative care and intensity of treatment at the end of life, quality of life, and quality of communication…
- Conditions
- Palliative Care, Kidney Failure, Chronic, Decision Making, Decision Support Techniques
- Trial name
- NCT04466865
- Testing
- Best Case/Worst Case communication tool training
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Wisconsin, Madison
End-Stage Renal Disease, Chronic Kidney Diseases
Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation
The study is a 2-arm randomized controlled trial among patients referred for kidney transplant evaluation at a single transplant center to compare the effects of a digital-analog intervention to increase living-donor kidney…
- Conditions
- End-Stage Renal Disease, Chronic Kidney Diseases, Kidney Transplant, Living Kidney Donor
- Trial name
- KT-CONNECT (NCT07072767)
- Testing
- Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided)
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- State University of New York at Buffalo
Chronic Kidney Failure, Hemodialysis Patients
Nature-Based Sound Application For Hemodialysis Patients
Chronic renal failure is one of the most common chronic diseases in the world and in our country. Hemodialysis is the most commonly used treatment method in the treatment of chronic renal failure.
- Conditions
- Chronic Kidney Failure, Hemodialysis Patients, Fatigue, Patient Comfort
- Trial name
- NBSAFHP (NCT06165211)
- Testing
- Nature sound listening, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Necmiye ÇÖMLEKÇİ
Chronic Kidney Failure
Hemodynamics in Chronic Kidney Disease
The goal of this observational study is to learn about the role of thoracic and whole body bioimpedance in the hemodynamic profile of patients with chronic kidney disease.
- Trial name
- HORUZ (NCT06987032)
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Chronic Renal Failure
Change From Baseline to Chronic Kidney Disease Patient Before and After Administration Drug
Chronic renal failure is a syndrome that renal function is decreased, and the patient number is increasing. In addition, patients on dialysis have also increased.
- Trial name
- NCT02378194
- Testing
- HD-003 (800mg/day), HD-003 (1600mg/day)
- Volunteers
- 62 people
- Sponsor
- Hyundai Pharmaceutical Co., LTD.
End Stage Renal Disease
HeRO Vascular Access Device Post Market Procedural Survey Protocol
Post market observational survey of a vascular access device for access-challenged patients. Data collection efforts focused on patient medical and access history and implant procedure results.
- Trial name
- PPS (NCT00889291)
- Volunteers
- 77 people
- Sponsor
- Merit Medical Systems, Inc.
End Stage Renal Disease
The Effects of Resistance Exercise and Protein Supplementation in Hemodialysis Patients
The objective of this study is to determine how protein supplementation, with or without exercise, affects functional capacity, strength, body composition, and physical activity in hemodialysis patients.
- Trial name
- NCT00179218
- Testing
- nutritional supplementation, exercise
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University
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