Clinical trials: Renal Regeneration
End Stage Renal Disease
PROlonged Ex-vivo Normothermic Machine PERfusion for Kidney Regeneration
The investigators would like to introduce and clinically evaluate prolonged normothermic machine perfusion (PNMP) to preserve and assess high-risk donor kidneys prior to transplantation.
- Trial name
- PROPER (NCT04693325)
- Testing
- Prolonged normothermic machine perfusion
- Where
- 2 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- Leiden University Medical Center
Hepatorenal Syndrome, Liver Regeneration
Plasma and Hemodynamic Markers During Hepatectomy
Introduction Liver resection is considered the only curative treatment option for mCRC patients without extrahepatic disease and is accepted practice.
- Trial name
- NCT01700231
- Testing
- Liver resection
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Chronic Renal Failure
Hyperbaric Oxygen Therapy for Renal Regeneration in Diabetic Nephropathy
Diabetes kidney disease is a leading cause for end stage renal disease in the western world. To date no treatment that can reverse renal damage exists.
- Trial name
- NCT03376282
- Testing
- Hyperbaric Oxygen oxygen therapy (HBOT)
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assaf-Harofeh Medical Center
Hepatorenal Syndrome, Liver Regeneration, AKI - Acute Kidney Injury
Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation
Hepatorenal Syndrome (HRS) is a serious complication that can occur in patients with liver cirrhosis, characterised by kidney dysfunction, or acute kidney failure (AKI).
- Conditions
- Hepatorenal Syndrome, Liver Regeneration, AKI - Acute Kidney Injury, Liver Transplant
- Trial name
- NCT07300709
- Testing
- renal biopsy
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The University of Hong Kong
End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria
Clinical Observation of Renal Function Reactivation Following a GRAS-Based Protocol in Patients With Chronic Kidney Disease and Long-Term Renal Arrest.
This observational study documents the impact of a specific oral protocol (based on FDA-GRAS ingredients) on patients with Stage 5 Chronic Kidney Disease (CKD).
- Conditions
- End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria, End-Stage Renal Disease (ESRD), Chronic Kidney Disease, Stage 5
- Trial name
- NCT07555327
- Testing
- CSR-CKD Oral Protocol
- Where
- Algeria
- Volunteers
- 8 people
- Sponsor
- Amar h Zireg
Chronic Kidney Disease(CKD), Myosteatosis
The Effect of the Nutraceutical (-)- Epicatechin on Myosteatosis in Patients With Advanced CKD
Some foods have components that can prevent and treat some diseases and provide beneficial effects for health. These components naturally occurring in foods are called nutraceuticals.
- Conditions
- Chronic Kidney Disease(CKD), Myosteatosis, Mitochondrial Dysfunction, Muscle Function
- Trial name
- EPIC-CKD (NCT06631820)
- Testing
- Epicatechin extract
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Glomerulonephritis, Lupus Nephritis
Cyclophosphamide and Fludarabine to Treat Lupus Nephritis
This study will test the safety and effectiveness of combination therapy with cyclophosphamide (Cytoxan) and fludarabine in treating lupus nephritis (kidney inflammation).
- Conditions
- Glomerulonephritis, Lupus Nephritis, Systemic Lupus Erythematosus
- Trial name
- NCT00001676
- Testing
- SQ Fludarabine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Sepsis
Plasticity and Regeneration of Renal Epithelial Cells
The incidence of acute kidney injury (AKI) among all hospitalized patients is approximately 7%. Among these patients, sepsis and septic shock remain the most important cause of acute renal failure (ARF) and account for more than…
- Trial name
- NCT02820142
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Renal Insufficiency, Chronic, Kidney Failure, Chronic
First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients
The goal of this first-in-human clinical trial is to examine the safety and efficacy of treatment with a new peritoneal dialysis (PD) device called WEAKID (WEarable Artificial KIDney for peritoneal dialysis).
- Conditions
- Renal Insufficiency, Chronic, Kidney Failure, Chronic, Chronic Kidney Diseases
- Trial name
- CORDIAL (NCT06314503)
- Testing
- WEAKID
- Where
- 3 sites in Italy, Netherlands and 1 more
- Volunteers
- 12 people
- Sponsor
- UMC Utrecht
Multiple Myeloma, Acute Kidney Injury
Effect of HFR-SUPRA in the Treatment of Multiple Myeloma-related Acute Kidney Injury
In patients with multiple myeloma-related acute kidney injury, compare the renal outcome of chemotherapy combined with HFR-SUPRA to chemotherapy combined with hemodialysis.
- Conditions
- Multiple Myeloma, Acute Kidney Injury, Hemodiafiltration With Ultrafiltrate Regeneration (HFR)
- Trial name
- NCT05429515
- Testing
- HFR-SUPRA, hemodialysis, Chemotherapy
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital