Clinical trials: Renal Surgeries
Acute Kidney Injury
A Clinical Score to Predict Acute Kidney Injury After Heart Valve Replacement Surgery
Acute kidney injury (AKI) is a common and severe complication of cardiac surgery. The main stay treatment remains preventive with no clear evidence supporting any therapeutic interventions.
- Trial name
- NCT04237636
- Where
- China
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Transplant Complication, Diabetic Nephropathy
Enhanced Recovery After Surgery for SPK Transplantation Recipients
108 patients underwent elective SPK surgery were randomly divided into ERAS group (E) and routine care group (T). The ERAS group was consisted of evidenced-based systematic optimization approaches, while the control group…
- Conditions
- Transplant Complication, Diabetic Nephropathy, Perioperative/Postoperative Complications
- Trial name
- NCT06095544
- Testing
- Enhanced recovery for SPK recipients
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery
Near Infrared Spectroscopy for the Detection of Acute Kidney Injury in Children Following Cardiac Surgery
One in a hundred children is born with a heart defect. Some children require heart surgery within the first few days of life, while others can wait until they are older.
- Conditions
- Acute Kidney Injury, Heart; Dysfunction Postoperative, Cardiac Surgery, Children
- Trial name
- NCT01382758
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pain, Postoperative, Nausea and Vomiting, Postoperative
Relieving Surgical Pain and Nausea With Light Therapy
The goal of this clinical trial is to investigate the effectiveness of colored (green and blue lens) glasses as a non-pharmacological method in relieving post-surgical pain and postoperative nausea in kidney donors.
- Trial name
- LITENS (NCT06772519)
- Testing
- green colored lens glasses, blue colored lens glasses, colorless (transparent) lens glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nuran Ayşen Pamir Aksoy
Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer
The goal of this observational study is to gather real-world information about Fear of Cancer Recurrence (FCR) following surgery in patients with renal cell carcinoma (RCC) and their partners/spouses by 1) establishing a panel…
- Trial name
- PP-RECURK (NCT07234656)
- Testing
- Phase 1: Establishment of a patient-partner panel, Phase 2: Feasibility testing of FCR questions, mode of administration and timing for investigating Fear of Cancer Recurrence
- Where
- 3 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigitta Rasmussen Villumsen
Acute Kidney Injury
Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury
The current international Continuous Renal Replacement Therapy (CRRT) replacement fluid doses of 35 ml/kg/h is better, but the result is according to white people, black people .
- Trial name
- NCT01560650
- Testing
- CRRT
- Where
- China
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Wei Shi
Renal Function Test, Urine Output, Lactate Level
Dopamine and Norepinephrine Infusion With Restricted Hydration
This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicator for tissue hypo perfusion…
- Trial name
- NCT03780686
- Testing
- Norepinephrine, dopamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Kidney Failure, Acute
Effect of Erythropoietin (EPO) in Kidney After Cardiac Surgery
The purpose of this study is to determine whether erythropoietin is effective in preventing acute kidney dysfunction after coronary artery bypass grafting surgery.
- Trial name
- EPO-CABG (NCT00654992)
- Testing
- Erythropoietin-Beta, Normal Saline
- Where
- South Korea
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D
Incidence and Prognostic of Cardiac Surgery-Associated Acute Kidney Injury: A Spanish Multicenter Study (SCARS-AKI)
To predict the renal damage caused by cardiac surgery in patients to try to mitigate it as soon as possible
- Conditions
- Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D, Acute Kidney Injury, Acute Kidney Disease
- Trial name
- SCARS-AKI (NCT07370831)
- Testing
- CARDIAC SURGERY
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Kidney Neoplasms
Prospective Randomized Study Comparing Laparoscopic Versus Open Partial Nephrectomy
Partial nephrectomy is considered the standard treatment for renal tumors smaller than 7 cm. With the evolution of image diagnostic tools and dissemination of its use, smaller tumors are being commonly diagnosed and treated.
- Trial name
- NCT01809119
- Testing
- Partial nephrectomy
- Where
- Brazil
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Acute Kidney Injury, Liver Injury
Blue Light Therapy for Liver Surgery
The investigators hypothesize that subjects undergoing liver resection and who are exposed preoperatively to high illuminance blue spectrum light will exhibit reduced organ injury, specifically liver dysfunction, than subjects…
- Conditions
- Acute Kidney Injury, Liver Injury, Inflammation
- Trial name
- NCT02915081
- Testing
- Blue light
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Renal Cell Carcinoma
Plasma Glycosaminoglycans as Diagnostic and Prognostic Biomarkers in Surgically Treated Renal Cell Carcinoma
In this study, the investigators profiled plasma glycosaminoglycans (GAGs) in a retrospective consecutive series of patients with a radiographic finding of renal mass referred to primary surgery for renal cell carcinoma (RCC).
- Trial name
- NCT03471897
- Testing
- Glycosaminoglycan plasma score
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Aki After Ascending Aortic Surgeries
Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic Surgeries
Acute kidney injury (AKI) is a frequent and serious complication after ascending aortic surgeries requiring cardiopulmonary bypass (CPB).
- Trial name
- NCT06958367
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Colon Cancer
Proteomic Analysis of Patients Undergoing Bariatric Surgery
The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery.
- Conditions
- Obesity, Colon Cancer, Thyroid Cancer, Esophageal Cancer
- Trial name
- NCT06787807
- Testing
- bariatric surgery
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Myomectomy; Surgical Blood Loss
Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy
Purpose is to identify if misoprostol in addition to local vasopressin decreases blood loss when compared to vasopressin alone, which is our current practice at this time.
- Trial name
- NCT03064568
- Testing
- Misoprostol 200Mcg Tab
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Postoperative Pain
TAP Blocks vs. IV Lidocaine for Kidney Transplants
This study will compare continuous intravenous lidocaine against single-injection transversus abdominis plane (TAP) block as a modality for postoperative analgesia in kidney transplant surgery.
- Trial name
- NCT03843879
- Testing
- Transversus Abdominis Plane Block, Intravenous Lidocaine
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Acute Kidney Injury, Hypotension
Is Permissive Hypotension Truly Harmless? Early Biomarker Evidence of Subclinical Kidney Injury in Rhinologic Surgery
This study aims to investigate the effects of permissive hypotension, which is routinely used in rhinologic surgeries such as rhinoplasty, septoplasty, and functional endoscopic sinus surgery (FESS), on renal function.
- Trial name
- NCT07328620
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Living Donor Nephrectomy
Scrotal Surgery After Laparoscopic Donor Nephrectomy
This study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar…
- Trial name
- NCT06716723
- Testing
- Nephrectomy
- Where
- Canada
- Volunteers
- 9,878 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's