Clinical trials: Renal Transplant Recipient
Kidney Transplantation
Donor Recipient Kidney Function Following Open Surgical vs. Laparoscopic Kidney Donation
This study will evaluate the differences between open surgical kidney donation and laparoscopic kidney donation on kidney donors and recipients.
- Trial name
- NCT00100516
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Transplant
iParent2Parent Peer Support Program for Parents of Pediatric Kidney Transplant Recipients
The iParent2Parent (iP2P) program is a new, innovative virtual mentorship program that will connect parents one-to-one with other parents of pediatric kidney transplant recipients who are trained to offer vital peer support and…
- Trial name
- NCT05968833
- Testing
- iParent2Parent Program
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Renal Disease, Renal Transplant
Comparison of Medication Adherence Between Once and Twice Daily Tacrolimus in Stable Renal Transplant Recipients
A critical aspect of real-world functioning following kidney transplantation involves how adherent individuals are to their medication regimens.
- Trial name
- NCT01334333
- Testing
- Tacrolimus - Prograf® twice daily formulation, Tacrolimus - Advagraf® once daily formulation
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University of British Columbia
CMV Infection, CMV
Letermovir vs Valganciclovir in CMV R+ Kidney Transplant
The purpose of this study is to find out whether letermovir can help prevent cytomegalovirus (CMV) infection in kidney transplant recipients who are CMV seropositive.
- Conditions
- CMV Infection, CMV, CMV Viremia, CMV Disease
- Trial name
- NCT07571135
- Testing
- Letermovir, Valganciclovir CMV Prophylaxis
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Elisabeth Kincaide
Chronic Renal Failure
The Impact of Early Protocol Biopsy in Kidney Transplant
The purpose of this study is evaluating the impact of steroid pulse therapy (SPT) on SCR revealed on PB in KT recipients maintained on TAC/MMF and corticosteroid.
- Trial name
- NCT02733510
- Testing
- methylprednisolone
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Kidney Disease, Chronic, Transplant Complication
Plant-based Diet for Kidney Transplant Recipients
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD).
- Conditions
- Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus
- Trial name
- NCT06186843
- Testing
- Plant-based diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- George Washington University
Kidney Failure, Kidney Diseases
Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Kidney Transplant
This is a proof of concept, single center study for the donation of HCV-positive kidney to HCV negative recipient patients, with preemptive, interventional treatment with 12 weeks of commercially available DAA therapy to prevent…
- Conditions
- Kidney Failure, Kidney Diseases, Hepatitis C
- Trial name
- NCT03623568
- Testing
- glecaprevir/pibrentasvir tablets
- Where
- United States
- Sponsor
- Raymond T. Chung, MD
Kidney Transplant Recipient, Diet Modification
Televideo Exercise and Nutrition Program for Kidney Transplant Recipients
The improvement in morbidity and mortality observed with kidney transplantation is often curtailed by post-transplant weight gain, which is common among kidney transplant recipients (KTR).
- Conditions
- Kidney Transplant Recipient, Diet Modification, Physical Activity
- Trial name
- NCT03697317
- Testing
- Televideo Lifestyle Coaching, Enhanced Usual Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kansas Medical Center
Evaluate the Risks of Using Arteriovenous Fistula as First Choise for Drug Administration
Use of Arterio-venous Fistula as First Choice for Intravenous Drug Administration in Kidney Transplant Recipients
Use of arteriovenous fistula for IV drug administration is controversial and often prohibited by nephrologists. However, we have been using this method in our department for years now in order to keep the patients 'veins for…
- Trial name
- PerFAV (NCT02874391)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Kidney Transplant, Transplant Recipients
AI-Assisted vs Usual Follow-up in Kidney Transplantation
The goal of this clinical trial is to learn whether kidney transplant follow-up visits run by a health professional using an artificial intelligence (AI) computer helper are as good as usual follow-up visits with a doctor.
- Trial name
- FOLLOW-KTx (NCT07842289)
- Testing
- AI-Assisted Follow-up Consultation, Usual Physician-Led Follow-up Consultation
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Atherosclerosis, Kidney Failure
Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients
The purpose of this study is to determine whether immunosuppression by tacrolimus, mycophenolate mofetil, and prednisone compared to conversion to sirolimus, mycophenolate mofetil, and prednisone affect the progression of…
- Trial name
- NCT00311311
- Testing
- tacrolimus, mycophenolate mofetil, prednisone
- Where
- 8 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- Pfizer
Renal Transplant Recipient, Immunized Against the Cytomegalovirus
Assessing the Risk of CMV Infection of the Renal Transplant About R + by Cellular Immunity Analyzed by the QuantiFERON ®-CMV Test.
Cytomegalovirus (CMV) infection was observed in over 30% of organ recipients with high morbidity. Moreover, no prophylaxis, 75% R + D-transplanted, 55%, R + D + and D-25% R + develop CMV.
- Trial name
- QUANTIC-R+ (NCT02064699)
- Testing
- CMV Infection
- Where
- 12 sites in France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Limoges
Renal Transplant Recipients
The Strategy in the Prevention of Renal Post-transplant Cytomegalovirus Infection Among Chinese Population
This study evaluates the safety and availability of oral valganciclovir(VGC) at the does of 450mg daily begin within 10 days after renal transplantation, and till to Day 100 posttransplant.
- Trial name
- NCT02973464
- Testing
- Valganciclovir, Ganciclovir
- Where
- China
- Volunteers
- 450 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Kidney Transplant; Complications, Diabetes Mellitus
Effect of Empagliflozin vs Linagliptin on Glycemic Outcomes,Renal Outcomes & Body Composition in Renal Transplant Recipients With Diabetes Mellitus
In the early postoperative period, hyperglycemia is frequently seen in renal transplant recipients primarily because of high doses of immunosuppressive therapy. Many of these patients have pre-existing type 2 diabetes (T2D).
- Trial name
- EmLinaRenal (NCT06095492)
- Testing
- Empagliflozin 25 MG, Linagliptin
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Medanta, The Medicity, India
Kidney Transplantation
A Dose Escalation Study in de Novo Renal Transplantation
The purpose of this study is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of escalating doses of TCD601 when compared to rATG in de novo renal transplant patients.
- Trial name
- NCT04311632
- Testing
- TCD601, Tacrolimus (TAC), Corticosteroids (CS)
- Where
- 4 sites in United States
- Volunteers
- 13 people
- Sponsor
- ITB-Med LLC
Renal Transplantation
This is a Two-year Follow-up Study to Evaluate the Long-term Safety, Tolerability and Efficacy of 2 Different Doses of Everolimus
This extension study is designed to provide long-term safety and efficacy data beyond 12 months up to Month 36.
- Trial name
- NCT00531063
- Testing
- Everolimus (RAD001)
- Where
- Switzerland
- Volunteers
- 237 people
- Sponsor
- Novartis Pharmaceuticals
Kidney Transplantation
Effect of Privigen Against Graft Loss
The principal objective of this pilot study is to determine whether the progression of chronic antibody-mediated rejection (ABMR) could be minimized by the post-transplant administration of high dose of Intravenous…
- Trial name
- InAuGuRAL (NCT02374736)
- Testing
- Privigen (Human normal immunoglobulin G (IgG > 98 % purity))
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC)
Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma
This is a phase II, multicenter, open label, single arm, non-randomized trial using Simon's optimal two-stage design to evaluate the efficacy of cemiplimab in kidney transplant recipients with advanced cutaneous squamous cell…
- Conditions
- Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC), Advanced Cutaneous Squamous Cell Carcinoma, Kidney Transplant
- Trial name
- CONTRAC-2 (NCT07715734)
- Testing
- Cemiplimab, Prednisone, Sirolimus
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Washington University School of Medicine
Kidney Transplantation, Liver Transplantation
Quality of Life in Pediatric Transplant Patients
The goal of this study is to compare parent and child perceptions of wellness and vulnerability in children who have undergone solid organ transplant.
- Conditions
- Kidney Transplantation, Liver Transplantation, Heart Transplantation
- Trial name
- NCT00678002
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Medical College of Wisconsin
Transplantation, Kidney Transplantation
Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets
The purpose of this study is to understand the pharmacokinetics of sirolimus tablets in different regimens in newly renal transplant patients, and the effect of dosage form conversion on the concentration of sirolimus in stable…
- Conditions
- Transplantation, Kidney Transplantation, Immunosuppression
- Trial name
- NCT00166842
- Testing
- sirolimus, cyclosporine, tacrolimus
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital