Clinical trials: Reproducibility
Healthy
Reproducibility of Malaria Challenge in Healthy Volunteers
This is a prospective, single arm, single intervention safety and immunogenicity study in 6 healthy, malaria-naive adults, conducted to demonstrate the successful implementation of the well-established malaria challenge model at…
- Trial name
- NCT01058226
- Testing
- Malaria challenge (wild-type NF54 strain Plasmodium falciparum sporozoites)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Diabetes
Reproducibility of HbA1c Measurement on the Aina HbA1c Monitoring System
A three site study to evaluate the reproducibility of the Aina HbA1c Monitoring System in quantitative determination of glycosylated hemoglobin (HbA1c) took place at the following sites: 1. Forsyth Institute in Cambridge, MA 2.
- Trial name
- NCT03232437
- Testing
- Aina HbA1c Monitoring System
- Where
- 3 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jana Care
Near-infrared Spectroscopy, Transition, Caesarean Section
Cerebral Oximetry in Newborns - Comparing INVOS 5100c and OxyPrem vs. 1.2
Regional tissue oxygenation (cStO2) can be monitored by near infrared spectroscopy. The commercial device INVOS 5100 (COVIDIEN, Mansfield, MA, USA) and the prototype OxyPrem vs.
- Trial name
- NCT01771601
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tooth Erosion
Preliminary Clinical Study of Ultrasound to Measure Enamel Thickness
The investigators have now established a technique to measure enamel thickness which has been shown to work well in-vitro. The teeth tested so far, obtained from the Dental School Tissue Bank, have been molars or pre-molars.
- Trial name
- UMET (NCT01622920)
- Testing
- Ultrasound transducer
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Normal Subjects
Reproducibility of Ankle Brachial Index After Maximal Exercise
Hemodynamic changes in the lower limbs are very important and rapid after maximal exercise. The automatic method allows a fastest measurement of the Ankle-Brachial Index (ABI).
- Trial name
- RICATEM (NCT01801579)
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
No Disease
A Study to Test the Repeatability and Reproducibility in Rod Intercept Time Within the AdaptDx Pro in Healthy Subjects With Normal Vision (FlashForward)
The purpose of this study is to test the repeatability and reproducibility in Rod Intercept (RI) time with two AdaptDx Pro devices in healthy subjects with normal vision.
- Trial name
- FlashForward (NCT07860905)
- Testing
- AdaptDx Pro
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AdaptDx, Inc.
Orthopedic
Intra and Inter- Observer Reproducibility of Ankle Dorsiflexion Measure With a New Tool
The Achilles' tendon is the largest and most resistant tendon in the body. When the triceps contracts, the Achilles' tendon is responsible for plantar flexion of the ankle.
- Trial name
- EQUINOM (NCT04792359)
- Testing
- Equinometer
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Musculoskeletal Diseases
Standardization and Reproducibility Regarding Scanning Procedures and Measurements of Weight-bearing Cone Beam CT in the Lower Extremity
Cone Beam CT (CBCT) of the knee is gaining interest, especially regarding patients suffering from patellofemoral instability. With this study investigators wish to investigate the day-to-day, test-retest reliability of weight…
- Trial name
- NCT05432609
- Testing
- Weight bearing CT
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Lung Function
Maximal Effort-dependent Respiratory Flow Rates
The general objective of this project is to determine the best method to measure maximal inspiratory flow rates, to study their reproducibility and create reference equations in healthy subjects.
- Trial name
- NCT03197701
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Functional Dyspepsia
Electrogastrogram (EGG) Reproducibility Study: EEG Readings in Normal Subjects and Dyspeptic Patients
The primary objective of this study is to determine whether EGG readings obtained from both normal subjects and dyspeptic patients are reproducible from one EGG recording to another on a different day.
- Trial name
- NCT00220883
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Temple University
Hip Joint
Intraobserver and Interobserver Reproducibility on Hip Clinical Assessment
The functional assessment of the hip joint is complex and challenging. Reproducible measures are necessary to identify changes in the structures and functionality of the hip joint over time and to evaluate the outcomes of…
- Trial name
- NCT03080727
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Stroke, Acute, TIA
Somatic Dysfunction in Patients With Acute Cerebrovascular Disease
The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in…
- Conditions
- Stroke, Acute, TIA, Reproducibility of Results, Osteopathic Manipulation
- Trial name
- SOMADC-AC (NCT06605014)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Near Infrared Spectroscopy
Cerebral Oximetry in Newborns - Comparing INVOS 5100 and FORE-SIGHT Cerebral Oximeters
Regional tissue oxygenation (rStO2) can be monitored by near infrared spectroscopy. The commercial devices FORE-SIGHT (CASMED) and INVOS (COVIDIEN) will be used simultaneously to test for their relative sensitivity for low oxygen…
- Trial name
- NCT01665287
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fasting, Fed
Development of the Leeds Food Preference Questionnaire in Spanish
The Leeds Food Preference Questionnaire (LFPQ) is a computer-based task used to measure reward responses and preferences for images of food.
- Trial name
- ES-LFPQ (NCT05837572)
- Testing
- Standardized meal
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Glaucoma
Heidelberg Edge Perimetry (HEP) Detecting Glaucomatous Visual Field Defects
The purpose of this study is to compare standard automated perimetry (SAP) using the Heidelberg Edge Perimeter (HEP) to the Octopus Visual Field (OVF) analyzer and determine test-retest reliability of both parameters in detecting…
- Trial name
- HEP (NCT02526654)
- Testing
- Heidelberg Edge Perimeter, Octopus Visual Field, Optical Coherence Tomography
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Sarcopenia
Evaluation of the Reproducibility of Jumping Mechanography
Sarcopenia, the age-related decline in muscle mass and function (widely recognized as "frailty"), is increasingly being appreciated, primarily in the research environment.
- Trial name
- Jump (NCT01164670)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Obstructive Pulmonary Disease
Reliability, Sensitivity and Validity of the 6 Minute Step Test in Chronic Obstructive Pulmonary Disease (COPD) Patients
Chronic Obstructive Pulmonary Disease (COPD) leads to a reduction in exercise capacity that affects the quality of life and increases mortality of these patients.
- Trial name
- NCT01298661
- Testing
- Six-minute Step Test
- Where
- Brazil
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Allergic Rhinitis, Rhinoconjunctivitis
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
To assess the reproducibility of the allergic response in the cat allergic subjects, measured as the change from baseline of the Total Nasal Symptom Score (TNSS) on the two challenge days.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Exposure
- Trial name
- NEC (NCT03414801)
- Testing
- Allergen Exposure
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Red Maple Trials Inc.
Genotyping Techniques
Spartan Cube CYP2C19 Inter Laboratory Reproducibilty Study
The study verifies that the Spartan Cube CYP2C19 System generates reproducible results under multi-variant conditions including test site (three different test sites), operators (two operators per site), testing days (five…
- Trial name
- NCT04473573
- Testing
- Spartan Cube CYP2C19 System
- Where
- 3 sites in Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.
Anesthesia, Regional
Intra-individual Reproducibility in Nerve Block Duration
An interventional randomized controlled crossover trial, to illuminate if durations in nerve block durations are predictable within the same subject.
- Trial name
- NCT03310047
- Testing
- Infusion, Lidocaine, 0.5%, 5 mL, Infusion, Lidocaine, 0.5%, 10 mL
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital