Clinical trials: Reproduction
Prostate Cancer, Sexual Dysfunction
Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Intensity-modulated radiation therapy (radiation directed at the tumor more precisely than in standard radiation therapy) may reduce damage to healthy…
- Conditions
- Prostate Cancer, Sexual Dysfunction, Sexuality and Reproductive Issues
- Trial name
- NCT00084552
- Testing
- radiation therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Fox Chase Cancer Center
Contraceptive Usage
Patient Centered Postpartum Contraception App
This study will evaluate a smart phone-based application ("app") designed to inform pregnant women ages 15-25 about their contraception options.
- Trial name
- NCT03402217
- Testing
- Patient Centered Postpartum Contraception App
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
HIV Testing, Contraceptive Usage
Adolescent Wellness Visits in Tanzania
This study evaluates the impact of clinic-based 'Adolescent Wellness Visits' (AWVs) coordinated with primary schools that offer a package of evidence-based adolescent-friendly preventative services on HIV testing uptake in…
- Trial name
- VITAA (NCT05306938)
- Testing
- Adolescent Wellness Visit
- Where
- Tanzania
- Volunteers
- 1,095 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infertility
Comparison Of The Embryoscope Time-Lapse System With Standard Embryo Culture
"Embryoscopes," allow for embryo culture to be performed in an automated incubation system under time lapse photography. Manufacturers of these systems (and investigators who have used these systems) claim that the availability…
- Trial name
- NCT02246309
- Testing
- Embryoscope Time Lapse System, Standard Embryo Culture
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Healthy Volunteers
The Effects of Reproductive Hormones on Mood and Behavior
This study evaluates the effects of estrogen and progesterone on mood, the stress response, and brain function in healthy women.
- Trial name
- NCT00001322
- Testing
- Leuprolide Acetate 3.75, Estradiol, Progesterone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Infertility
Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles
The purpose of the study is to compare the pain experience between the patients that have had their transvaginal oocytes retrieval with ultrasound guidance performed with reduced single lumen needle (Vitrolife Sweden AB…
- Trial name
- NCT00924885
- Testing
- Swemed Follicle Aspiration Set Reduced Single Lumen, Swemed Follicle Aspiration Set Single Lumen (1.4 mm)
- Where
- 4 sites in Sweden
- Volunteers
- 257 people
- Sponsor
- Vitrolife
Perimenopausal Depression
Perimenopausal Effects of Estradiol on Reward Responsiveness
Using neuroimaging, the investigator will study the effects of estrogen on mood and brain function in perimenopausal women either with or without depression.
- Trial name
- PEERS (NCT02255175)
- Testing
- Estradiol, Progesterone
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Fertility
Dysregulation of FSH in Obesity: Functional and Statistical Analysis
Excess maternal weight, especially obesity, influences almost every aspect of fertility, from conception to problems during pregnancy.
- Trial name
- NCT02478775
- Testing
- Degarelix (GnRH antagonist), recombinant FSH, Cetrorelix
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Reproductive Issues, Reproductive Disorder
An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data
Aim to investigate the efficacy of follitropin alpha biosimilar therapy (Primapur®) in nonselected real-world population.
- Conditions
- Reproductive Issues, Reproductive Disorder, Fertility Disorders, Fertility Issues
- Trial name
- NCT04854707
- Testing
- Follitropin Alfa, Follicle Stimulating Hormone/Luteinizing Hormone
- Where
- 35 sites in Russia
- Volunteers
- 5,484 people
- Sponsor
- IVFarma LLC
Malignant Female Reproductive System Neoplasm
Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies
This phase IV trial studies how well liposomal bupivacaine with or without hydromorphone works in improving pain control during the first 24 hours after surgery in patients with gynecological malignancies undergoing laparotomy.
- Trial name
- NCT04258631
- Testing
- Hydromorphone, Laparotomy, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Obesity, Infertility
Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
The sole purpose of this study is to evaluate pathophysiology of disease. The disease state that is being evaluated is the obesity-related alterations in reproductive hormones The obesity epidemic in the United States is…
- Trial name
- NCT01381016
- Testing
- Estradiol, Gonadotropin-releasing hormone (GnRH), Progesterone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypogonadism, Kallmann Syndrome
Follicle Stimulating Hormone (FSH) to Improve Testicular Development in Men With Hypogonadism
Men with idiopathic hypogonadotropic hypogonadism (IHH, Kallmann Syndrome) may have small testicular size, low testosterone levels, no history of puberty, and infertility.
- Trial name
- NCT00064987
- Testing
- Testicular biopsy, gonadotropin releasing hormone (GnRH), follicle stimulating hormone (FSH)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cervical Cancer, Breast Cancer
Sexual Health Empowerment for Women's Health
The purpose of this study is to expand the reach of an existing cervical cancer literacy and prevention intervention- the Sexual Health Empowerment (SHE) Project .
- Conditions
- Cervical Cancer, Breast Cancer, Contraceptive Usage, Sexually Transmitted Diseases
- Trial name
- SHE-WOMEN (NCT03984695)
- Testing
- SHE-WOMEN
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Reproductive Sterility
Prednisolone Improves IVF Outcomes in Men With Anti-sperm Antibodies
Corticosteroids have been indicated to treat men with ASAs. Although many studies have confirmed the clinical therapeutic significance of corticosteroids in the treatment of men with ASAs, other studies have not found a…
- Trial name
- NCT02935738
- Testing
- Prednisolone treatment
- Volunteers
- 241 people
- Sponsor
- Barz IVF Center for Infertility Treatment and Embryo Research
Reproductive Tract Infections
Evaluation of Immediate v. Delayed CT/NG Test for Treatment in the ED
The purpose of this study is to determine if immediate availability of GeneXpert® CT/NG test results reduces the overtreatment rate for ED patients with suspected gonorrhea or chlamydia and to assess changes in clinician…
- Trial name
- NCT01989130
- Testing
- Roche AMPLICOR CT/NG, Cepheid Xpert CT/NG Test
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Washington University
Neoplasms, Colorectal Neoplasms
A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
This study will evaluate the efficacy and safety of alectinib in participants with Anaplastic Lymphoma Kinase (ALK)-positive locally advanced or metastatic solid tumors other than lung cancer.
- Conditions
- Neoplasms, Colorectal Neoplasms, Melanoma, Pancreatic Neoplasms
- Trial name
- ALpha-T (NCT04644315)
- Testing
- Alectinib
- Where
- 29 sites in United States
- Volunteers
- 1 people
- Sponsor
- Hoffmann-La Roche