Clinical trials: Reproductive Condition
Body Weight, Contraceptive Usage
Oral Contraceptives and Body Mass Index
The main hypothesis for this study is that increased Body Mass Index (BMI) alters oral contraceptive metabolism in a manner which results in decreased effectiveness in obese women.
- Trial name
- NCT01170390
- Testing
- All participants (Aviane), Portia, Aviane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hiv
Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention
Following on the heels of large implementation science projects that participated in the launch of widespread daily oral PrEP availability, investigators will launch and study the integration of novel PrEP products - beginning…
- Trial name
- PrEMIA (NCT07076043)
- Testing
- Multiple Product PrEP Program, Routine Oral PrEP
- Where
- Kenya
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Iron-deficiency, Anemia
Iron-Biofortified Rice Intervention in the Philippines
The objective of this randomized efficacy feeding trial was to determine the effects of consuming iron-biofortified rice on iron status in women, compared to non-biofortified rice.
- Trial name
- NCT04623918
- Testing
- Iron-biofortified rice, Control rice
- Where
- Philippines
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cornell University
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Heat Stress, Pregnancy
Indigenous Nutritional Supplements for Pregnancy to Improve Resilience in Environmental Heat
The purpose of this study is to learn whether a simple, traditional, and balanced meal made from local foods, eaten once a day during pregnancy, can help women in rural Pakistan stay healthier in hot weather and give birth to…
- Conditions
- Heat Stress, Pregnancy, Women of Reproductive Age, Nutrition Status
- Trial name
- INSPIRE (NCT07489664)
- Testing
- Indigenous Balanced Diet Arm
- Where
- Pakistan
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Contraception, Sexually Transmitted Diseases
Contraceptive Awareness and Reproductive Education
The purpose of this study is to increase the initiation and continuation of highly effective contraceptive use while incarcerated and upon release, as well as decrease unsafe sexual activity.
- Conditions
- Contraception, Sexually Transmitted Diseases, Pregnancy
- Trial name
- CARE (NCT01132950)
- Testing
- Motivational Interviewing, Didactic Educational Counseling
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Male Reproductive Problem
The Effects of Cannabis on Male Reproductive Functions
The purpose of this study is to understand the direct effects of cannabis on male reproductive functions. The investigators plan to conduct a double-blind, placebo-controlled clinical trial to examine both the chronic and acute…
- Trial name
- NCT06755346
- Testing
- Cannabis plant (THC 20mg), Cannabis (0%/ THC / 0% CBD), Cannabis plant (THC 40mg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kanako Hayashi
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Environmental Enteric Dysfunction (EED), Malnutrition
The Maternal EED Study
Undernutrition among women of reproductive age is more common in South Asia than in any other region. In South Asia, the prevalence of maternal undernutrition varies between 10 and 40%.
- Conditions
- Environmental Enteric Dysfunction (EED), Malnutrition, Women of Reproductive Age, Gut Microbiota
- Trial name
- NCT05862363
- Testing
- Microbiota-directed balanced energy protein (MD-BEP), Ready-to-use supplementary food-balanced energy protein (RUSF-BEP), Esophagogastroduodenoscopy (EGD)
- Where
- Bangladesh
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Substance-Related Disorders, Sexually Transmitted Diseases
Adolescent Drug and HIV Prevention in South Africa
The purpose of this trial is to test the effectiveness of a classroom-based prevention program (HealthWise: Learning Life Skills for Young Adults) to reduce the risk of HIV/AIDS and STIs, as well as substance use, among…
- Trial name
- NCT00336180
- Testing
- HealthWise South Africa curriculum
- Where
- South Africa
- Volunteers
- 7,695 people, healthy volunteers welcome
- Sponsor
- Penn State University
Neural Tube Defects, Folic Acid Deficiency
Salt-FA to Increase Folate Levels
Question: How effective is folic acid-fortified iodized salt in increasing serum folate concentrations among non-pregnant and non-lactating women of reproductive age? Hypothesis: Folic acid-fortified iodized salt can increase…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
- Trial name
- NCT06174883
- Testing
- Folic acid fortified iodized salt
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hydrocephalus and Neuroscience Institute
Maternal Death
Maternal Health Service Utilization Among Women of Reproductive Age in Sidama Region, Ethiopia
Introduction: Maternal health service (MHS) utilization helps to decrease maternal morbidity and mortality. However, the existing evidence is not sufficient to design effective and efficient strategies.
- Trial name
- MHSU (NCT05865873)
- Testing
- Health education
- Where
- Ethiopia
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- Hawassa University
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Iron Deficiency Anemia
Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women
Iron deficiency (ID) anemia (IDA) is a global public health problem, with the highest prevalence in Africa. Vaccines often underperform in low- and middle- income countries (LMIC), and undernutrition, including ID, likely plays a…
- Trial name
- NCT05919472
- Testing
- Oral iron supplementation (pre-treatment), COVID-19 vaccine, MenACWY vaccine
- Where
- Kenya
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Sexual Behavior, Adolescent Behavior
Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)
Child Trends will conduct a randomized control trial evaluation of Parent Toolkit 2.0, an innovative intervention for parents and caregivers of middle and high school students.
- Conditions
- Sexual Behavior, Adolescent Behavior, Sexually Transmitted Diseases, Contraception Behavior
- Trial name
- NCT06579781
- Testing
- Morehouse Family Health Study's Parent Toolkit 2.0, Morehouse Family Health Study's General Health Guide
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Child Trends
Pregnancy Prevention, Sexual Behavior
Project Legacy Impact Evaluation Study
This study will design and rigorously evaluate the efficacy of Project Legacy, a five week positive youth development intervention to decrease sexual risk for unintended pregnancies and STIs among youth experiencing homelessness…
- Conditions
- Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
- Trial name
- NCT03366636
- Testing
- Project Legacy
- Where
- 12 sites in United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert