Clinical trials: Resolution
Psoriatic Arthritis
Distal Erosions and Nail Psoriasis
Nearly 30% of patients with cutaneous psoriasis (PsO) developed psoriatic arthritis (PsA). Among these patients 20 % will have severe destructive arthritis.
- Trial name
- PSUPSO (NCT02813720)
- Testing
- HR-pQCT High resolution peripheral quantitative CT-scan
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Ineffective Esophageal Motility, GERD (Gastroesophageal Reflux Disease)
The Influence of Specialized Food Products Based on Ice-Cream on Esophageal Motility
This study aims to assess the influence of specialized products based on ice cream on esophageal motility
- Trial name
- MICE (NCT07121803)
- Testing
- specialized food based on ice cream, order 1, specialized food based on ice cream, order 2, specialized food based on ice cream, order 3
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Alzheimer Disease, Mild Cognitive Impairment Due to Alzheimer's Disease
Alzheimer's Disease Multinuclear Imaging Neuro-Enhanced Resolution (AD-MINER)
This single-center prospective cohort study will enroll 750 participants (250 cognitively Normal (CN) individuals, 250 with mild cognitive impairment (MCI), and 250 with Alzheimer's disease (AD)).
- Trial name
- AD-MINER (NCT07089303)
- Where
- China
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Breastfeeding, Breast Milk Expression
The Effect of Hypno-breastfeeding and Solution-oriented Approach
Motivation, which is also necessary for the breastfeeding behavior of mothers in the postpartum period, can affect the success and continuity of breastfeeding.
- Trial name
- NCT05599542
- Testing
- Solution-oriented approach, Hypno-breastfeeding
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Clinical Trials, Phase I as Topic
First in Human Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1214784
This study is a first in human study that will investigate the safety, tolerability and pharmacokinetics of ascending single doses of BAY1214784 using a placebo controlled, randomized, single center design.
- Trial name
- NCT02212080
- Testing
- BAY1214784
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bayer
Androgenetic Alopecia
Assessment of Dutasteride Topical Solution in Male Androgenetic Alopecia
This is a randomized, open-label phase 1/2a study designed to evaluate the pharmacokinetics, pharmacodynamics, and safety of AD-303A (topical formulation) and AD-3031 in male patients with androgenetic alopecia.
- Trial name
- NCT07490327
- Testing
- AD-303A, AD-3031
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Moogene Medi Co., Ltd
Pulmonary Arterial Hypertension
Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers
This study is designed to investigate the safety and tolerability of AIR001 Inhalation Solution when administered under conditions of hypoxia and to identify dose levels of drug resulting in a reduction in pulmonary arterial…
- Trial name
- AIR001-CS02 (NCT00814645)
- Testing
- Sodium Nitrite Inhalation Solution
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Aires Pharmaceuticals, Inc.
Hemodynamic Instability
The Cold Fluids Study
In this single center crossover study the aim is to investigate the effect of Ringer's lactate solution at high and low temperatures on physiological response in healthy adults.18 healthy volunteers will be included.
- Trial name
- NCT05610254
- Testing
- Ringer's Lactate
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Amyloid, Systemic Amyloidosis
Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP)
This study is based on the hypothesis that MRI could make it possible to non-invasively detect these amyloid deposits at the level of the wrist using parametric sequences known as T1 mapping, in the form of an extension of T1 in…
- Trial name
- AMYLOCARP (NCT05150353)
- Testing
- MRI
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Healthy
Study Comparing 2 New Formulations of HKI-272 in Healthy Adult Subjects
To evaluate the comparative bioavailability of 2 new tablet formulations of HKI-272 with a reference capsule and an oral solution in healthy subjects.
- Trial name
- NCT00498745
- Testing
- neratinib
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Puma Biotechnology, Inc.
Cystic Fibrosis
Tobramycin Inhalation Solution Administered by eFlow Rapid Nebulizer: Scintigraphy Study
This study assesses the aerosol delivery characteristics (measured by in vivo lung deposition, nebulization time, serum tobramycin concentrations, and pharmacokinetic parameters) and safety of tobramycin inhalation solution…
- Trial name
- NCT00399945
- Testing
- Tobramycin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Novartis
Smoking Cessation
Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects
Transdermal nicotine delivery systems are a cigarette smoking cessation aid designed to deliver nicotine into the systemic circulation via the skin.
- Trial name
- NCT03178422
- Testing
- CQSS2, NicoDerm CQ Patch
- Where
- 5 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chrono Therapeutics, Inc.
Healthy Volunteers
In Vitro Study of Platelets Collected on Trima Accel System and Stored in InterSol Solution
This study sought to verify that the in vitro quality (functional assays) of platelets collected on the Trima Accel system, Version 6.4, diluted in InterSol Solution, and stored for 1, 5, and 7 days meet FDA requirements.
- Trial name
- NCT02298842
- Testing
- Platelets stored in InterSol, Platelets stored in Plasma
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Terumo BCT
Healthy
Open-label, Bioequivalence Study of Certolizumab Pegol 200 mg Solution Injected Either by a Prefilled Syringe (Reference) or by an E-Device (Test) in Healthy Subjects
This is a single center, open-label, Phase 1 bioequivalence (BE) study in healthy subjects designed to demonstrate the bioequivalence of a single dose of certolizumab pegol (CZP) 200mg when injected by means of a prefilled…
- Trial name
- NCT02806219
- Testing
- Prefilled syringe (PFS), e-Device
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- UCB BIOSCIENCES, Inc.
Autism Spectrum Disorder, Language Development
HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at…
- Conditions
- Autism Spectrum Disorder, Language Development, Neurocognitive Disorders, Child Language
- Trial name
- EE-TSA-LANG (NCT05586672)
- Testing
- EEG-HR, ADI-R, ADOS-2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Educational Problems
Lab Skills Nursing Education Into Effective Clinical Practice During COVID-19: Elsevier Clinical Skill Platform
This study aimed to investigate the effectiveness of utilizing an Elsevier clinical skill platform in clinical nursing education. 1.2. Research hypotheses 1.
- Trial name
- EDU (NCT04977921)
- Testing
- lab session
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Breastfeeding Avoidance and Breastfeeding Self-efficacy
Effect of Solution-Focused Approach Education on Breastfeeding Avoidance and Breastfeeding Self-Efficacy in Primiparous Mothers
Breastfeeding provides important short- and long-term benefits for maternal and infant health. However, many women, particularly primiparous mothers, experience psychological, social, and physiological difficulties during…
- Trial name
- NCT07899593
- Testing
- Solution-Focused Approach Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Emotional Distress, Well-Being, Psychological
The Efficacy of Online Brief Positive Cognitive Behavior Therapy Compared to Traditional Cognitive Behavior Therapy
Positive Cognitive Behavioral Therapy (P-CBT) has emerged as the fourth Cognitive Behavioral Therapy waive, based on critiques brought to Cognitive Behavioral Therapy for being grounded in the deficit-based medical model.
- Conditions
- Emotional Distress, Well-Being, Psychological, Performance
- Trial name
- NCT06436521
- Testing
- Positive Cognitive Behavioral Therapy, Traditional Cognitive Behavioral Therapy
- Where
- Romania
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Healthy
A Study to Demonstrate the Equivalence of the Tofacitinib Oral Solution to the Tablet Formulation in Healthy Participants.
This is a Phase 1, randomized, open label, 2 period, 2 sequence, cross over, single dose study to evaluate the AUC equivalence, and safety of tofacitinib 5 mL oral solution (1 mg/mL) and 5 mg tablet in healthy participants.
- Trial name
- NCT04111614
- Testing
- Tofacitinib tablet, Tofacitinib Oral Solution
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Antisepsis
Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate
The present study evaluates the effects of bactericidal load reduction after surgical hand scrub antisepsis using the reference antiseptic product propan-ol-1 60% as control versus a surgical hand scrub antisepsis with addition…
- Trial name
- sorbectol (NCT04454619)
- Testing
- Hand antisepsis with Clorhexidine and solution
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
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