Clinical trials: Resolution
Latrodectism
Pharmacokinetic Study Protocol of ANAWIDOW Lyophilized Powder for Solution for Intravenous Use in Fasting Conditions
A single-dose, open-label, single-treatment, single-period pharmacokinetic study under fasting conditions, in 12 healthy adult. To evaluate the single dose pharmacokinetic profile ANAWIDOW [antivenin latrodectus (black widow)…
- Trial name
- NCT04848714
- Testing
- ANAWIDOW [antivenin latrodectus (black widow) equine immune F(ab)2] lyophilized powder for solution 10 mL
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Postmenopause
Study Evaluating Three Bazedoxifene/Conjugated Estrogens Combination Tablet Formulations Versus BZA Oral Solution
This study involves the experimental drug bazedoxifene acetate/conjugated estrogens (also called BZA/CE). This drug is not approved by the Food and Drug Administration (FDA). About 24 subjects will take part in this study.
- Trial name
- NCT00367536
- Testing
- bazedoxifene/conjugated estrogens combination tablet
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Anal Dysplasia, Human Papillomavirus
The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Infection by certain high-risk oncogenic types of HPV (HR-HPV) is the major cause of several cancers in men, notably squamous cell carcinoma…
- Conditions
- Anal Dysplasia, Human Papillomavirus, Anal Cancer
- Trial name
- HPV-SAVE (NCT02503111)
- Testing
- The Hyfrecator ® 2000 Electrosurgical System, Observation Alone
- Where
- 4 sites in Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
SARS CoV 2 Infection
Use of a Hypochlorous Acid Spray Solution in the Treatment of COVID-19 Patients : COVICONTROL Study .
The objective is To evaluate the efficacy and safety of nasal spray and mouth spray application with hypochlorous acid-containing solution versus placebo as a curative treatment for hospitalized SARS-CoV-2 positive patients And…
- Trial name
- COVICONTROL (NCT05862480)
- Testing
- Spray with Hypochlorous Acid Group
- Where
- Tunisia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Monastir
IBS (Irritable Bowel Syndrome)
High-Resolution Measurements of Diet-Microbiome Interactions
The goal of this clinical trial is to characterize regional intestinal fermentation physiology and determine how the response to fermentable dietary fiber differs between healthy individuals and individuals with irritable bowel…
- Trial name
- NCT07856823
- Testing
- Inulin, Low-fiber control breakfast shake, Atmo Gas-Sensing Capsule
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Substance Use Disorders (SUDs)
Cogito: A Turnkey Solution for Rapidly Developing, Evaluating, Deploying, and Scaling Digital Therapeutics
This is a research study to evaluate the usability of the Cogito digital therapeutics development platform. The Cogito platform is designed to allow researchers who are seeking to embed an evidence-based behavioral therapy into a…
- Trial name
- NCT07104396
- Testing
- Cogito digital therapeutics development platform
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Square2 Systems, Inc.
Healthy Subjects
Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution
This is a randomised, open-label, 3-period, crossover single dose study to assess the relative bioavailability of two formulations of HTL0016878: an oral solution of HCl salt form (the reference product) and an oral capsule…
- Trial name
- NCT04935320
- Testing
- HTL0016878.HCl Solution 10 mg, HTL0016878.Citrate Capsule 10 mg
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nxera Pharma UK Limited
Hydrocortisone, Depression
Exploring the Effects of Corticosteroids on the Human Hippocampus
Chronic corticosteroid (CS) exposure is associated with changes in memory and the hippocampus in both humans and in animal models.
- Conditions
- Hydrocortisone, Depression, Healthy Volunteers
- Trial name
- NCT03896659
- Testing
- Hydrocortisone Oral
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Grief
Accelerated Resolution Therapy for Early Maladaptive Grief
The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs).
- Trial name
- NCT05624879
- Testing
- Accelerated Resolution Therapy, Information and Support
- Where
- 4 sites in United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Educational Problems, Anatomical Pathological Condition
3D Resin Printed Fracture Models for Anatomy Education
Resin printing is an emerging technology with a wide array of applications. This research seeks to assess the practicality of incorporating 3D resin printed models into anatomy education while investigating how fractured models…
- Trial name
- NCT06061003
- Testing
- Clinical Anatomical Education with Fractured Bone Models, Clinical Anatomical Education with Standard Bone Models
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gambling
Biomarkers of Online Gambling Addiction
The purpose of this study is to identify alterations of motivational processes related to decision making in uncertainty condition associated with gambling addiction: by studying the dynamics between brain systems involved in…
- Trial name
- BLUNDER (NCT02862821)
- Testing
- HR-EEG
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Healthy Volunteers
A Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men
ASP0367 is a potential new treatment for people with Duchenne Muscular Dystrophy and Mitochondrial Myopathies. Before ASP0367 is available as a treatment, the researchers need to understand how it is processed by and acts upon…
- Trial name
- NCT05217901
- Testing
- 14C-labeled ASP0367
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Undergoing Esophagogastroduodenoscopy (EGD)
High Resolution Optical Imaging of the Esophagus Using the Nvision Volumetric Laser Endomicroscopy (VLE™) Imaging System
This is a single center, single arm, open label observational trial of patients undergoing EGD. The primary objective of this clinical trial is to evaluate the ability of physicians to position the NvisionVLE catheter to acquire…
- Trial name
- NCT01844921
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NinePoint Medical
Healthy, Colonic Motility
High Resolution Colonic Manometry in Relation to 3D-Transit Times in Healthy Controls.
Background: Within recent years, new methods for detailed assessment of gastrointestinal (GI) motility have been developed. Hence, the electromagnetic 3D-Transit system is a safe, non-invasive method for detailed description of…
- Trial name
- NCT04231721
- Testing
- High Resolution Colonic Manometry and 3D-Transit system
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Janne Ladefoged Fassov
Tuberculosis
Study of Latent Tuberculosis Infection (LTBI) by High Resolution Scanner
It is traditionally considered that someone with a positive tuberculin skin test (TST) (and/or positive result in Cell Interferon-Gamma Release Assay (TIGRA), depending on the different countries' guidelines) is infected but not…
- Trial name
- GRANLATHU (NCT00904956)
- Where
- 3 sites in Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Pulmonary Arterial Hypertension
Safety, Tolerability, & Pharmacokinetics Study of Single & Multiple Inhaled Doses of Imatinib Inhalation Solution
This is a randomised, double-blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, and PK of single and multiple inhaled doses of imatinib inhalation solution (AER-901) in healthy adult…
- Trial name
- NCT04903730
- Testing
- AER-901 Solution for Nebulization
- Where
- Australia
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Aerami Therapeutics
HGF, Fibroblast
Effects of Chlorhexidine on Human Gingival Fibroblasts
This prospective in vitro study aims to evaluate the effects of two chlorhexidine-based mouthwash formulations on the survival and function of human gingival fibroblasts (hGFs).
- Conditions
- HGF, Fibroblast, Chlorhexidine, Cytotoxicity
- Trial name
- NCT07669636
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Obesity, Type II Diabetes
Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior
The field of neuroeconomics has begun to elucidate neural mechanisms underlying self-control; however, researchers have not yet harnessed neuroeconomics findings to develop interventions for improving self-control ability.
- Conditions
- Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
- Trial name
- NCT01801254
- Testing
- STRIDES
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Anismus, Incontinence
Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry
To assess whether HR-ARM (High resolution Anorectal Manometry) performed in the more naturalistic / physiological upright, seated position on a commode provides a more valid assessment of anorectal function and simulated…
- Trial name
- SEAT (NCT02633592)
- Testing
- HRARM, MRI Defecography
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Skin Manifestations
Effectiveness, Safety, and Cost Efficacy of Water (H2O) as a Substitute for Sodium Bicarbonate (NaHCO3) Plus Solution in Neutralization of Chemical Peeling Using 35% Glycolic Acid Solution
Chemical peeling is an applied procedure which creates controlled destruction of all layers of the epidermis or dermis, subsequently causes exfoliation followed by regeneration of layers with the final result of improved texture…
- Trial name
- NCT04154436
- Testing
- Sodium Bicarbonate (NaHCO3) Plus Solution, Water (H2o)
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
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