Clinical trials: Resolution of Pathologic Process
Scaphoid Fracture, Scafoïd; Fracture
Diagnostics of Scaphoid Fractures With HRpQCT
The scaphoid bone is the most common fractured carpal bone. Scaphoid fractures represent 2-6% of all fractures and occur mainly in young, active patients aged 15 to 40.
- Trial name
- NCT03899025
- Testing
- CT
- Where
- Netherlands
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VieCuri Medical Centre
ICU Patients Requiring a Central Venous Access
Chlorhexidine vs Povidone Iodine in Alcoholic Solutions for Prevention of Central Venous Catheter Infection
The best antiseptic solution for cateheter care remains unknown.High concentration in aquous solution or low concentration in alcoholic solution of chlorhexidine actbetter than povidone iodine in aquous solutions.
- Trial name
- NCT00259350
- Testing
- Skin disinfection
- Where
- France
- Volunteers
- 520 people
- Sponsor
- Poitiers University Hospital
Obesity
Changes in Body Composition Following Bariatric Surgery
Obesity is an important public health issue worldwide. In the United States, the percentage of overweight and obese adults increased from 47 and 15%, respectively, to 69 and 36% in the last 40 years.
- Trial name
- NCT02148068
- Testing
- Bariatric Surgery
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Peter Nau
Healthy Subjects
Normative Metrics of High-Resolution Anorectal Manometry With the Use of Water-perfused System in a Healthy Russian Cohort
High resolution anorectal manometry (HRAM) normative values are still need to be studied in different populations and with the use of different (solid-state and water-perfused) systems.
- Trial name
- NCT03897296
- Testing
- High resolution anorectal manometry, water perfused catheter
- Where
- 2 sites in Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Depression
Collaborative Multidimensional Intervention for Depression in Chile
This study protocol aims to determine the efficacy of a collaborative multidimensional model (CMD) to improve the results of depression in primary care (PHC) in Chile.
- Trial name
- CMID (NCT05016388)
- Testing
- Collaborative Multidimensional Model (CMD), Standard Model (SM)
- Volunteers
- 394 people
- Sponsor
- University of Talca
Cognitive Impairment
Determining the Impact of Shunting and CerebroVascular Reactivity on 7T MRI (DISCoVeR 7T MRI)
The purpose of this study is to use transcanial doppler (TCD) ultrasound to look for possible risk factors for ischemic brain injury.
- Trial name
- DISCoVeR (NCT03291340)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Pennsylvania
Supraventricular Arrhythmia, Atrial Fibrillation
Non-invasive Differentiation of Supraventricular Tachyarrhythmia
1. Questionnaire for supraventricular tachycardia: About history and targeted diagnosis of supraventricular tachycardia 2. Extended Signal-averaged ECG for detailed P-Wave analysis and to calculate a virtual atrial…
- Trial name
- NIDSA (NCT06061120)
- Testing
- Recording of an extended high-resolution ECG
- Where
- Germany
- Volunteers
- 1,250 people
- Sponsor
- RWTH Aachen University
Deafness
Tradeoff Between Spatial and Temporal Resolution
In this study, investigators will examine how temporal rate processing might be affected when the width of neural excitation narrows.
- Trial name
- NCT03867058
- Testing
- Electrode selection/electrode configuration
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Pain, Postoperative
TEMporal PostOperative Pain Signatures
The purpose of this research study is to determine what causes pain after surgery to increase or decrease over time.
- Trial name
- TEMPOS (NCT02407743)
- Testing
- Surgical patients' clinical progression, Genetic markers
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- University of Florida
Corneal Dystrophy
Correlation Between In-vivo Anatomy of Corneal Dystrophies as Assessed by High- Resolution Optical Coherence Tomography (OCT) Measurement and Histological Examination
Corneal dystrophies are usually classified histopathologically according to the layer of the cornea that is affected. The International Committee for the Classification of Corneal Dystrophies (IC3D) takes this anatomical…
- Trial name
- NCT03461991
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- 2 sites in Austria
- Volunteers
- 2 people
- Sponsor
- Medical University of Vienna
Postoperative Pain
Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates
This study is being done to try to learn more about how a child's body breaks down bupivacaine, a local anesthetic medication that is being used for pain control.
- Trial name
- NCT01557985
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Immune Response To Sepsis, Staphylococcus Aureus Infection
Immune Resolution After Staphylococcus Aureus Bacteremia
The purpose of this study is to determine how monocyte HLA-DR and other markers of immune function change with time in patients with and without prior immune dysfunction who survive sepsis from Staphylococcus aureus bacteremia.
- Trial name
- NCT01879761
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Chicago
Normal Eyes, Age Related Macular Degeneration
High Resolution Imaging OCT Study
The goal of this pilot study is to compare image quality between the investigational devices (R1 and HighRes OCT) and the SPECTRALIS (cleared) in adult participants with normal and/or pathology eyes.
- Conditions
- Normal Eyes, Age Related Macular Degeneration, Diabetic Retinopathy, Eyes With Retinal Diseases
- Trial name
- NCT07338461
- Testing
- Autofluorescence Imaging, Infrared reflectance imaging, OCT imaging
- Where
- Italy
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Esophageal Achalasia, Esophageal Motility Disorders
POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia
Achalasia is a disorder of the esophagus in which the muscular valve between the esophagus and the stomach fails to relax, and the body of the esophagus loses its normal coordinated squeezing movement.
- Conditions
- Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux
- Trial name
- POEM-HD (NCT07814027)
- Testing
- Peroral endoscopic myotomy, Laparoscopic Heller myotomy with Dor fundoplication
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Minia University
Oral Cavity Neoplasm
Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery
This clinical trial studies wide-field and high resolution in vivo imaging in visualizing lesions in patients with abnormal or uncontrolled oral cell growth (neoplasia) undergoing surgery.
- Trial name
- NCT01269190
- Testing
- High-Resolution Microendoscopy, Multispectral Imaging, Proflavine
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- M.D. Anderson Cancer Center
Metabolic Syndrome, Physical Activity
The Effect of Health Provider's Feedback on Physical Activity Surveillance Using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome
The Effect of Health Provider's Feedback on Physical Activity Surveillance using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome; a 12-Week Randomized Control Study
- Trial name
- NCT05630456
- Testing
- Receving feedback, No regular feedback
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Laryngeal Neoplasms, Head and Neck Cancers
MRI Laryngeal Imaging With a Surface Coil
To determine if high resolution MRI can detect early invasion of cartilage by laryngeal carcinoma, and to determine if high resolution MRI may be superior to conventional MRI imaging or CT imaging to detect cartilage invasion.
- Conditions
- Laryngeal Neoplasms, Head and Neck Cancers, Larynx Cancer
- Trial name
- NCT00965003
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Obstetric Anal Sphincter Injury
A Comparison of THD® Anopress With High Resolution Anorectal Manometry
Currently, high resolution anorectal manometry (HDARM) is used as gold standard to measure anal sphincter pressures in women who have sustained a third or fourth degree perineal tears (obstetric anal sphincter injuries).
- Trial name
- NCT07083908
- Testing
- THD® Anopress (Sensyprobe) first, High Resolution Anorectal Manometry first
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Acute Kidney Injury, Shock
Normal Saline Versus Balance Salt Solution Resuscitation on Kidney Function
The purpose of this study is to determine Acute kidney injury incidence between sterofundin and normal saline ; Resuscitation shock patients
- Trial name
- NCT02520804
- Testing
- sterofundin, normal saline
- Where
- Thailand
- Volunteers
- 107 people
- Sponsor
- Mahidol University
Sepsis, Acute Kidney Injury
Comparison of Balanced Crystalloids and Normal Saline in Septic Patients
In this prospective randomized controlled trial, investigators attempt to study the effects of acetated Ringer's solution on the prognosis and renal function of patients with sepsis in intensive care unit compared with normal…
- Conditions
- Sepsis, Acute Kidney Injury, Septic Shock, Sepsis, Severe
- Trial name
- NCT03685214
- Testing
- 0.9% saline, lactated Ringer's solution
- Where
- China
- Volunteers
- 500 people
- Sponsor
- ZhiYong Peng
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