Clinical trials: Resorption
Postmenopausal Osteoporosis
Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption
The aim of the study is to assess the relative antiresorptive properties of 2 osteoporosis medications when combined with teriparatide.
- Trial name
- NCT01750086
- Testing
- Teriparatide 40-mcg subcutaneous injection, Denosumab Injection, Alendronate Oral Tablet
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bone Resorption, Stress Fracture
The Effects of NSAIDs on Bone Metabolism Following Exercise
The purpose of this study is to determine the effects of a single dose of non-steroidal anti-inflammatory drugs on post-exercise markers of bone and muscle metabolism.
- Conditions
- Bone Resorption, Stress Fracture, Bone Injury
- Trial name
- NCT05512013
- Testing
- Ibuprofen 800 mg, Celecoxib 200mg, Flurbiprofen 100 mg
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Lung Collapse, Lung Diseases
The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool
HYPOTHESIS: During anesthetic pre-oxygenation with high FiO2, pulmonary atelectasis occur, especially in patients < 6 years old, where FRC and pulmonary closing volume may overlap.
- Conditions
- Lung Collapse, Lung Diseases, Atelectasis, Atelectasis Without Respiratory Distress Syndrome
- Trial name
- NCT04506203
- Testing
- Air test
- Where
- 3 sites in Argentina, Spain
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth, Deciduous
3Mixstatin ,Tri-Antibiotic Mix & Simvastatin in the Treatment of Primary Molars
The aim of this study is to determine whether the success rate of pulp therapy undergone on primary molars with signs and symptoms of odontogenic infection that may render them indicated for extraction will improve with the use…
- Trial name
- NCT03585751
- Testing
- Pulpectomy for primary molars + triple antibiotic mix, Pulpectomy for primary molars + 3mixstatin, Pulpectomy for primary molars + simvastatin
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Diagnoses Disease
Effect of Cone Beam Computed Tomography on Diagnostic and Therapeutic Decision Making
this study will determine the effect of CBCT examinations on diagnostic and therapeutic decision making in endodontics.
- Trial name
- NCT04689126
- Testing
- surgical or nonsurgical endodontic treatment
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Bone Resorption, Bone and Bones
Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults
Nutrient intake of calcium and protein are known to function as regulators of bone remodeling. Specifically, a balanced rate of bone resorption and bone formation (i.e.
- Trial name
- NCT05533502
- Testing
- Combined Plant-Based Protein and Marine-Based Multi-Mineral Supplement
- Where
- Ireland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Dental Implant
Accuracy of Guided Ridge Splitting With Simultaneous Implant Placement
Assessing whether is there a difference between computer-guided ridge splitting and conventional technique with simultaneous implant placement in patients with maxillary width deficiency.
- Trial name
- NCT06333912
- Testing
- dental implant placement with ridge splitting.
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Bone Loss, Alveolar, Dental Implant Failed
Clinical and Radiographic Evaluation of Bone and Tissue Level Single Unit Implants: Two-piece Abutment Concept
Dental implants have become one of the most common treatments used for the rehabilitation of lost teeth. The success rate of dental implant treatment is quite high.
- Trial name
- NCT05592821
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Bone Resorption
Comparison of Three Transmucosal Augmentation Techniques in Immediate Implant Placement
Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT).
- Trial name
- NCT06820489
- Testing
- Conventional connective tissue graft after immediate implant placement, Scarf connective tissue graft after immediate implant placement, Dual zone concept after immediate implant placement
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Ghent
Vibration; Exposure
Effect of Mechanical Vibration on Root Resorption
The aim of this study was to investigate the effect of mechanical vibration on root resorption with or without the application of orthodontic force.
- Trial name
- NCT04686617
- Testing
- Mechanical Vibration
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Alveolar Bone Resorption
TiO2-scaffolds for Alveolar Ridge Preservation
The goal of this clinical trial is to evaluate the safety of placing TiO2 scaffolds in alveolar ridge and to evaluate if the scaffold material contributes to maintain the anatomy and the volume of the alveolar process after tooth…
- Trial name
- TIOSCAFF (NCT06269497)
- Testing
- Scaffold placement, CBCT
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Alveolar Bone Resorption
LPRF Block vs. DBBM in Horizontal Bone Reconstruction
split-mouth RCT. 12 patients. horizontal GBR performed. 2 grafts were compared: test was LPRF block, control was 50% autogenous bone and 50% DBBM. 25 months follow-up.
- Trial name
- NCT07584629
- Testing
- guided bone regeneration
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bone Loss, Alveolar
Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh
Evaluation of clinical and radiographical amount of bone gained using customized 3D printed zirconia barrier compared to titanium mesh in combined ridge defect at the esthetic zone.
- Trial name
- NCT06559605
- Testing
- zirconia barrier, titanium mesh
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Resorption
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)
the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
- Trial name
- NCT04434703
- Testing
- Platelet rich fibrin (PRF), Advanced platelet rich fibrin (A-PRF), blood clot
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Pathological Resorption of External Root
3D Evaluation of Clear Aligners Versus Fixed Orthodontic Treatment of Lower Anterior Crowding
Evaluate and compare clear aligners versus fixed orthodontic treatment of lower anterior crowding with the use of cone-beam computed tomography within maximum 6 months or until correction of lower anterior crowding whichever is…
- Trial name
- NCT06510569
- Testing
- U lab aligners, oramco bracket
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haidy Fekry