Clinical trials: Resorption
Alveolar Process Atrophy, Smoking, Cigarette
Platelet Rich Fibrin Treatment for the Alveolar Ridge Preservation in Smokers
Bone healing is affected by smoking, particularly healing of extraction sockets, showing deficiencies in vertical and horizontal bone dimensions compared to the healing of non-smokers.
- Conditions
- Alveolar Process Atrophy, Smoking, Cigarette, Platelet-Rich Fibrin
- Trial name
- NCT06190860
- Testing
- Autologous Leukocyte and platelet-rich fibrin, Intraoral Scan, Computed Tomography
- Where
- 2 sites in Chile
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Preparation of the Implant Site With Piezosurgery vs Drill
Observational Study on the Preparation of the Implant Site With Piezosurgery vs Drill: Comparison Between the Two Methods in Terms of Post-operative Pain, Surgical Times and Operational Advantages
Purpose: Recent advances showed that ultrasonic implant site osteotomy is related with a decreased trauma and a better post operative healing of the surgical site if compared to the traditional drilling techniques.
- Trial name
- NCT03978923
- Testing
- preparation of the implant site with Piezosurgery vs drill
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Alveolar Bone Resorption, Tooth Extraction
Ridge Preservation Following Tooth Extraction
An animal study and our pilot human study demonstrated that placing a smooth-surface titanium bone screw (TBS) over the buccal plate of an extraction socket resulted in less dimensional changes of the alveolar ridge along with no…
- Trial name
- NCT05485194
- Testing
- Reducing dimensional changes following tooth extraction
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Obesity
Relationships Between GLP-2 and Markers of Bone Turnover Following Feeding
This study has been designed to study differences bone turnover in relation to glucagon-like peptide-2 (GLP-2) following feeding in lean and obese premenopausal women.
- Trial name
- GLP-2 (NCT01531907)
- Testing
- Study visit procedures
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Bone Resorption, Tooth Loss
Hyaluronic Acid Effect on Xenogenic Bone Healing
The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation.
- Trial name
- NCT04377256
- Testing
- Ridge preservation: Tooth extration and immediat bone grafting in the socket
- Where
- 2 sites in Lebanon
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Root Resorption
The Effect of Two Different Types of Forces on Possible Root Resorption in Relation to Dentin Phosphoprotein Levels
External root resorption is a common unfavourable sequel of orthodontic treatment. Although diagnosis of root resorption is usually done by radiographs; they are technique sensitive.
- Trial name
- NCT04825665
- Testing
- Continuous force, Intermittent force
- Where
- 2 sites in Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sherifa Ghaleb
Maxillary Sinus Disease, Periodontal Bone Loss
Association Between Periodontal Bone Loss and Maxillary Sinus Changes.
AIM AND OBJECTIVES: AIM To determine the association between periodontal bone loss and maxillary sinus changes through cone beam computed tomography. OBJECTIVES Primary objectives- 1.
- Trial name
- NCT04702867
- Where
- India
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Alveolar Bone Loss
Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
This study is intended to evaluate the efficiency of graftless maxillary sinus augmentation with concentrated growth factor (CGF) utilizing "dynamic implant valve approach" (DIVA) system.
- Trial name
- NCT02985645
- Testing
- maxillary sinus augmentation with CGF, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Dental Implant Failed, Platelet-rich Fibrin
Evaluation of Dental Implants Placed in Preserved and Non-preserved Post-extraction Ridges
A prospective study to evaluate and compare implants placed in preserved versus non-preserved extraction sockets using L-PRF (Leucocyte- and platelet-rich fibrin) after 1, 3 and 5 years.
- Conditions
- Dental Implant Failed, Platelet-rich Fibrin, Alveolar Rege Preservation, Alveolar Bone Loss
- Trial name
- NCT03715439
- Testing
- Dental implant
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Alveolar Bone Resorption
Bone Formation Maxillary Sinus Width
According to previous scientific evidence lining on biological concept of bone regeneration into the maxillary sinus, an observational study was set up to record possible (hypothesized) difference in bone formation between…
- Trial name
- NCT04830670
- Testing
- sinus floor elevation with lateral approach
- Where
- 3 sites in Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss, Dental Implant Failed
Linear Micro-Perforation Osteotomy Ridge Split Approach
The traditional ridge split technique might be performed simultaneously with implant placement, resulting in a shortened treatment time.
- Trial name
- LMPO (NCT06887595)
- Testing
- Free-hand linear micro perforation osteotomy and ridge splitting, AI-assisted/computer-guided linear micro perforation osteotomy and ridge splitting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Bone Loss
The Influence of Cortical Bone Perforation on Guided Bone Regeneration in Humans
The purpose of this randomized clinical trial was to evaluate the effect of cortical bone decortication on the angiogenesis and osteogenesis of augmented ridge by GBR.
- Trial name
- NCT02741752
- Testing
- Decortication
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Osteoporosis, Postmenopausal
Soluble Corn Fiber Effect on Bone Resorption in Post Menopausal Women
This study is designed to study the dose response effect of continuous Soluble Corn Fiber (SCF) intake over a 50 day period on bone resorption in healthy post menopausal women using the 41Calcium methodology.
- Trial name
- NCT02416947
- Testing
- 0 g SCF, 10g SCF, 20g SCF
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Purdue University
Bone Resorption Disorder
Guided Bone Regeneration in Atrophic Anterior Maxillary Ridges
This study is aiming to evaluate clinically, radiographically ,and histologically GBR using collagen membrane in combination with a mixture of ABBM and autogenous particulated bone compared to collagen membrane with ABBM in…
- Trial name
- NCT03731416
- Testing
- GBR by xenograft and autogenous bone
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Bone Loss, Alveolar
Esthetic Outcomes of Single Immediate Implant Placement
A randomized controlled trial of 12-month duration to compare gingival margin location, buccal horizontal ridge dimensions, and interproximal crestal bone levels following two surgical approaches for immediate placement of…
- Trial name
- NCT02435706
- Testing
- Flapless immediate implant placement, Flap assisted immediate implant placement, Implant and temporary crown
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alveolar Bone Loss
Bone Height Gain Following Transcrestal Sinus Floor Elevation Using Piezoelectric Surgery Versus The Conventional Osteotome Technique
Missing teeth usually result in functional and cosmetic deficits. Traditionally, they have been restored with dentures or fixed bridges.
- Trial name
- NCT03944811
- Testing
- piezoelectric device, Summers technique
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Asymmetry, Fat Atrophy
The Fat Analysis Trial (FAT) - Assessing the Impact of Lipo-aspirate Processing
Fat grafting has been gaining popularity over the past decade. It is now commonly used for breast augmentation and reconstruction, however a major challenge remains the high rate and unpredictable rate of fat resorption…
- Trial name
- NCT05318716
- Testing
- Fat grafting - Revolve device, Fat grafting - Decantation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's