Clinical trials: Resorption
Alveolar Bone Resorption
Autogenous Ramus Bone Block Harvesting With Piezosurgery
The aim of this randomized prospective clinical trial was to evaluate the outcome of bone block harvesting from the retromolar region using the Conventional and Piezosurgery Method.
- Trial name
- NCT05548049
- Testing
- Bone harvesting from ramus area with piezosurgery for autogenous bone augmentation, Bone harvesting from ramus area with conventional burs for autogenous bone augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marmara University
Bone Loss, Osteoclastic, Bone Loss, Alveolar
Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
This study aims to evaluate bone formation in grafts in terms of its quality (density), quantity (volume) and maturation obtained with the application of a tissue-engineered bone grafting compound containing concentrated…
- Conditions
- Bone Loss, Osteoclastic, Bone Loss, Alveolar, Alveolar Bone Loss, Alveolar Bone Atrophy
- Trial name
- NCT04998058
- Testing
- Maxillary sinus floor elevation grafting with synthetic bone substitute.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Alveolar Bone Loss, Tooth Extraction
Platelet Rich Fibrin (PRF) in Socket Preservation Technique
The loss of a tooth or change in its function is lead to a change in alveolar ridge's height and volume. Socket preservation (SP) is a procedure designed to prevent or limit alteration of the post-extraction bone ridge to achieve…
- Trial name
- NCT06173492
- Testing
- Dental extraction, Platelet Rich Fibrin
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Naples
Alveolar Bone Loss
Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole (sticky demineralized tooth releasing metronidazole) versus autogenous demineralized…
- Trial name
- NCT06374784
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole, Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF, Alveolar ridge preservation using autogenous demineralized dentin graft alone
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Pocket
Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT05631600
- Testing
- Manuka honey
- Where
- Croatia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Resorption of Mandible
3D Assessment of Mandibular Bone Loss Via STL Superimposition After Complete Denture Occlusal Adjustment
STL registration-based superimposition is an advanced technique for assessing mandibular bone resorption in removable complete denture (RCD) patients.
- Trial name
- NCT06562972
- Testing
- Occlusal equilibration of complete denture using articulating paper, Occlusal equilibration of complete denture using occulosense
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Badr University
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Alveolar Bone Resorption
Evaluation of Socket Shield Technique With Immediate Implant Placement in the Esthetic Zone
The study was conducted on 20 immediate implant placement sites in the anterior maxillary region. In the study group, 10 implants were inserted using socket shield technique, while in control group, 10 implants were inserted…
- Trial name
- NCT05409950
- Testing
- Immediate implant placement using socket shield technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Egyptian Russian University
Alveolar Bone Resorption
Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation
In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the Bio-Oss Collagen underwent alveolar ridge preservation using Bio-Oss Collagen and the Sticky Bone group using Sticky…
- Trial name
- NCT05902689
- Testing
- alveolar ridge preservation with bio-oss collagen, alveolar ridge preservation with sticky bone
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dental Implant, Bone Resorption
Influence of Abutment Shape on Peri-implant Marginal Bone Loss
A study designed as a randomized controlled trial of parallel group design will be conducted at the Dental clinic of the University of Valencia to evaluate the influence of 2.5 mm high abutments with different shapes…
- Trial name
- NCT03888339
- Testing
- Commercially available high abutments placement, Modified shape abutments
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Alveolar Bone Loss, Loss of Teeth Due to Extraction
Evaluation of OSSIX-Plus Resorbable Collagen Membranes for Alveolar Ridge Preservation Following Exodontia
The purpose of this study is to evaluate clinically, histologically and radiographically the healing of extraction sockets covered with a resorbable collagen membrane (OSSIX-Plus) 12 weeks following exodontia.
- Conditions
- Alveolar Bone Loss, Loss of Teeth Due to Extraction, Edentulous Alveolar Ridge
- Trial name
- OSSIX (NCT00639860)
- Testing
- OSSIX-Plus
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- William Giannobile
Alveolar Bone Loss
Vitamin D and Periodontitis
Vitamin D has become important for periodontal disease due to play a role in autoimmunity, bone mineral metabolism and inflammation.
- Trial name
- NCT03088488
- Testing
- fasting venous blood samples
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Bone Resorption, Bone Atrophy
The Effects of Low Energy Availability and High Impact Jumping on Markers of Bone (re)Modelling in Females
Osteoporosis is worldwide health epidemic categorized by poor bone health, primarily diagnosed by low bone mineral density, and costs healthcare systems billions every year.
- Conditions
- Bone Resorption, Bone Atrophy, Energy Supply; Deficiency, Female Athlete Triad
- Trial name
- NCT04790019
- Testing
- Low energy availability, High impact jumping
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Bone Remodeling, Energy Metabolism
Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism
Bone is a metabolically active tissue undergoing continuous remodeling through the coordinated actions of osteoclasts (resorption), osteoblasts (formation), and osteocytes (regulation).
- Trial name
- OVAD (NCT07454252)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Bone Resorption
State of the Art Immediate Implant Placement in the Premaxilla
The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns.
- Trial name
- NCT07080710
- Testing
- Immediate implant placement
- Where
- 2 sites in Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Ghent
Alveolar Bone Loss, Bone Density Increased
Minimally Invasive Ridge Augmentation
The present study is a human, prospective, randomised controlled clinical trial conducted to explore the outcome of a minimally invasive ridge augmentation technique with and without low level laser therapy.
- Trial name
- NCT04190576
- Testing
- Low Level Laser Therapy
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Ridge Preservation, Alveolar Bone Loss
Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned.
- Conditions
- Ridge Preservation, Alveolar Bone Loss, Dentin Graft
- Trial name
- NCT05437172
- Testing
- injectable platelet rich fibrin with demineralized dentin graft, demineralized dentin graft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Implants, Alveolar Bone Loss
Evaluation of Immediate Implant Placement In The Esthetic Zone Using the Bone Shielding Concept Versus Dual Zone Therapy
Immediate implant placement has proven to be a successful treatment procedure that is preferred by patients because of being less traumatic, more time-efficient.
- Conditions
- Immediate Implants, Alveolar Bone Loss, Dual Zone Technique, the Bone Shielding Concept
- Trial name
- NCT05381467
- Testing
- immediate implant placement with The Dual-Zone Therapeutic Concept, Immediate implant placement with the bone shielding concept
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laser, Intrusion
Histological Change of The Dentinal-Pulp Complex and Root Resorption
The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.
- Conditions
- Laser, Intrusion, Histology, Resorption
- Trial name
- NCT01642693
- Testing
- Low power laser in teeth after intrusive movement, Simulated laser in teeth with intrusive movements
- Where
- Colombia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia