Clinical trials: Resorption
Edentulism, Bone Atrophy, Alveolar
Short Implants in Atrophic Posterior Maxilla
This study aims to evaluate the clinical and radiological outcomes of short implants in the rehabilitation of single-tooth edentulism in the posterior maxilla.
- Conditions
- Edentulism, Bone Atrophy, Alveolar, Sinus Pneumatization
- Trial name
- NCT06759246
- Testing
- implant placement
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Orthopedic Disorder, Calcium Metabolism Disorders
High- Versus Low-calcium Water for Bone Health
The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different exposures: low-calcium water…
- Conditions
- Orthopedic Disorder, Calcium Metabolism Disorders, Bone Resorption, Water-Electrolyte Imbalance
- Trial name
- NCT05772364
- Testing
- Loading of low-calcium water first, then high-calcium water
- Where
- Italy
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Alveolar Bone Loss
Histomorphometric and Tomographic Assessment on the Influence of the Placement of a Collagen Membrane Subjacent the Sinus Mucosa After Maxillary Sinus Floor Augmentation
the purpose of the study is to look for differences in dimensional variations of augmented maxillary sinuses with or without the placement of a collagen membrane subjacent the sinus mucosa.
- Trial name
- NCT03902457
- Testing
- Maxillary sinus augmentation
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Alveolar Bone Resorption
Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft
The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs.
- Trial name
- NCT05484492
- Testing
- demineralized and mineralized combination putty bone allograft, calcium phosphosilicate putty alloplast graft
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Buccal Bone Thickness
Buccal Bone Resorption in Immediate Implants in Thin and Thick Buccal Plates of Bone in Esthetic Zone
To achieve esthetic immediate implants a minimum of adequate buccal bone thickness must be present. It was postulated that 2 mm of buccal bone thickness was needed to prevent recession of the buccal plate.
- Trial name
- NCT04630665
- Testing
- immediate implant placement
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis
The Interaction Between Calcium and Vitamin D Intake
We will study the relative importance of high calcium intake and vitamin D supplementation for calcium homeostasis, as determined by serum parathyroid hormone (PTH) and biochemical bone markers.
- Trial name
- PTH Modified (NCT00762775)
- Testing
- Calcium and vitamin D supplementation
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Alveolar Bone Loss
Effect of Buccal Fat Pad Derived Stem Cells in Maxillary Sinus Augmentation
In this study the buccal fat pad derived stem cells (BFPSCs) will be harvested from buccal fat pad tissue of patients receiving maxillary sinus augmentation.
- Trial name
- NCT02745379
- Testing
- BFPSCs+ DFDBA+ PRF, DFDBA + PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Alveolar Bone Loss
Wedge Implant Narrow Crests: Multi-center Clinical Study
This study was designed as a multicentric prospective clinical trial to assess the clinical, biological and patient's perceived success of new wedge-shaped dental implants inserted in narrow ridges.
- Trial name
- NCT03290729
- Testing
- wedge shape implants insertion
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Evaluation of Erythropoietin on Alveolar Ridge Preservation
regenerative materials would help in decreasing post-extraction resorption in sites indicated for placement of a conventional bridge or prosthetically driven implant.
- Trial name
- NCT06513039
- Testing
- Erythropoietin carried on chitosan carrier, chitosan carrier
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Clinical Efficacy
Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft
The purpose of this study is to compare two methods of ridge preservation in the maxillary anterior esthetic zone to determine the best method to establish adequate bone and soft tissue to accommodate implant placement.
- Trial name
- NCT01431131
- Testing
- Intrasocket graft, Intrasocket plus facial overlay graft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Atrophic Maxilla
Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
- Trial name
- NCT05400044
- Testing
- Three dimensional maxillary bone augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Demineralized Dentin Graft With Hydrochloric Acid Versus Nitric Acid in Alveolar Ridge Preservation
The reduction in alveolar bone dimensions is an inevitable outcome after tooth extraction due to the healing events that results in bone modeling/remodeling.
- Trial name
- DDG (NCT04393714)
- Testing
- Alveolar ridge preservation after extraction
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Alveolar Bone Loss, Periodontal Diseases
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation
Tooth extraction triggers a cascade of biological events mediated by the local inflammatory response following surgical intervention and by the loss of masticatory stimulation to the periodontium.
- Conditions
- Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy
- Trial name
- NCT07573761
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Extraction Socket Healing, Extraction, Tooth
The Effect of Collagen In Tooth Extraction Procedures
This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the…
- Trial name
- NCT07270510
- Testing
- Collagen Matrix soft tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Periodontal Bone Loss
Application of Hyaluronic Acid in the Treatment of Periodontitis
The aim of the present investigation will be evaluated the healing of suprabony defects following surgical flap elevation and hyaluronic acid application respect to surgical flap elevation alone.
- Trial name
- NCT05073575
- Testing
- Hyaluronic acid, No-hyaluronic acid
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Alveolar Bone Loss
Bone Mineral Density and Periodontal Status in Patients on Antiepileptic Drug
Assessment of bone mineral density and periodontal parameters in patients with epilepsy. Comparative evaluation of bone mineral density and levels of marginal alveolar bone in patients with epilepsy on monotherapy, combination…
- Trial name
- NCT04262999
- Testing
- effect of sodium valproate on alveolar bone level, effect of levetiracetam on alveolar bone level, effect of sodium valproate+levetiracetam on alveolar bone level
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Osteoporosis
A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)
This study will assess the safety, tolerability, PK, and PD of a once weekly dose of MK0822 in healthy postmenopausal women.
- Trial name
- NCT00770159
- Testing
- odanacatib
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Edentulous, Alveolar Process Atrophy
Evaluation of Implant Stability Changes in Sites Prepared with Different Osseodensification Techniques: a Prospective Observational Clinical Study
The goal of this observational study is to compare, within a cohort of patients requiring rehabilitation in two different sites of the premolar area in the upper maxilla, the primary and secondary stability of implants placed in…
- Trial name
- NCT06679894
- Testing
- Implant site preparation with osteotomes and electrified mallet, Implant site preparation with osseodensification drills
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Bone Health, Nutrition Status
Optimizing Vitamin D Status During Initial Military Training
The primary objective of this randomized, double-blind, placebo-controlled trial is to determine the effect of vitamin D and calcium supplementation (800IU and 2000mg, respectively) on biochemical indicators of nutritional status…
- Trial name
- NCT01617109
- Testing
- Ca/Vit D
- Where
- 2 sites in United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine